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5WYJ
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BU of 5wyj by Molmil
Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ...
Authors:Ye, K, Zhu, X, Sun, Q.
Deposit date:2017-01-13
Release date:2017-03-29
Last modified:2019-10-09
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017
5UPK
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BU of 5upk by Molmil
CDC42 binds PAK4 via an extended GTPase-effector interface - 3 peptide: PAK4cat, PAK4-N45, CDC42
Descriptor: Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Ha, B.H, Boggon, T.J.
Deposit date:2017-02-03
Release date:2017-12-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:CDC42 binds PAK4 via an extended GTPase-effector interface.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4YDH
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BU of 4ydh by Molmil
The structure of human FMNL1 N-terminal domains bound to Cdc42
Descriptor: Cell division control protein 42 homolog, Formin-like protein 1, MAGNESIUM ION, ...
Authors:Kuhn, S, Anand, K, Geyer, M.
Deposit date:2015-02-22
Release date:2015-05-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:The structure of FMNL2-Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation.
Nat Commun, 6, 2015
5C2J
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BU of 5c2j by Molmil
Complex structure of the GAP domain of MgcRacGAP and Cdc42
Descriptor: ALUMINUM FLUORIDE, Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Murayama, K, Kato-Murayama, M, Hosaka, T, Kitamura, T, Yokoyama, S, Shirouzu, M.
Deposit date:2015-06-16
Release date:2016-06-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of G-protein target alternation of MgcRacGAP by phospholylation
To Be Published
8SCZ
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BU of 8scz by Molmil
Cryo-EM structure of 14aa-GS RIG-I in complex with p3SLR30
Descriptor: Antiviral innate immune response receptor RIG-I, ZINC ION, p3SLR30
Authors:Wang, W, Pyle, A.M.
Deposit date:2023-04-06
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of 14aa-GS RIG-I in complex with p3SLR30
To Be Published
8S5I
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BU of 8s5i by Molmil
Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, basal state, single particle reconstruction
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5L
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BU of 8s5l by Molmil
Full-length human cystathionine beta-synthase, basal state, partially degraded tetramer
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8SD0
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BU of 8sd0 by Molmil
Cryo-EM structure of RIG-I in complex with p3SLR14
Descriptor: Antiviral innate immune response receptor RIG-I, ZINC ION, p3SLR14
Authors:Wang, W, Pyle, A.M.
Deposit date:2023-04-06
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of RIG-I in complex with p3SLR14
To Be Published
8S5J
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BU of 8s5j by Molmil
Full-length human cystathionine beta-synthase, basal state, helical reconstruction
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5K
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BU of 8s5k by Molmil
Full-length human cystathionine beta-synthase, basal state, single particle reconstruction
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5H
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BU of 8s5h by Molmil
Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, basal state, helical reconstruction
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5M
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BU of 8s5m by Molmil
Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, SAM bound, activated state, helical reconstruction
Descriptor: Cystathionine beta-synthase, S-ADENOSYLMETHIONINE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
6J30
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BU of 6j30 by Molmil
yeast proteasome in Ub-engaged state (C2)
Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ...
Authors:Cong, Y.
Deposit date:2019-01-03
Release date:2019-03-20
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.
Mol. Cell, 73, 2019
6J2N
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BU of 6j2n by Molmil
yeast proteasome in substrate-processing state (C3-b)
Descriptor: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
Authors:Cong, Y.
Deposit date:2019-01-02
Release date:2019-03-20
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.
Mol. Cell, 73, 2019
6J2C
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BU of 6j2c by Molmil
Yeast proteasome in translocation competent state (C3-a)
Descriptor: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
Authors:Cong, Y.
Deposit date:2019-01-01
Release date:2019-03-13
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.
Mol. Cell, 73, 2019
6J2X
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BU of 6j2x by Molmil
Yeast proteasome in resting state (C1-a)
Descriptor: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASOME REGULATORY SUBUNIT RPN5, 26S proteasome complex subunit SEM1, ...
Authors:Cong, Y.
Deposit date:2019-01-03
Release date:2019-03-13
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.
Mol. Cell, 73, 2019
6J2Q
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BU of 6j2q by Molmil
Yeast proteasome in Ub-accepted state (C1-b)
Descriptor: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
Authors:Cong, Y.
Deposit date:2019-01-02
Release date:2019-03-13
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.
Mol. Cell, 73, 2019
8TO0
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BU of 8to0 by Molmil
48-nm repeating structure of doublets from mouse sperm flagella
Descriptor: Cilia- and flagella- associated protein 210, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ...
Authors:Chen, Z, Shiozak, M, Hass, K.M, Skinner, W, Zhao, S, Guo, C, Polacco, B.J, Yu, Z, Krogan, N.J, Kaake, R.M, Vale, R.D, Agard, D.A.
Deposit date:2023-08-02
Release date:2023-11-01
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking.
Cell, 186, 2023
8U4O
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BU of 8u4o by Molmil
Structure of CXCL12-bound CXCR4/Gi complex
Descriptor: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Saotome, K, McGoldrick, L.L, Franklin, M.C.
Deposit date:2023-09-11
Release date:2024-03-13
Last modified:2024-10-02
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structural insights into CXCR4 modulation and oligomerization.
Nat.Struct.Mol.Biol., 2024
4BKG
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BU of 4bkg by Molmil
crystal structure of human diSUMO-2
Descriptor: SMALL UBIQUITIN-RELATED MODIFIER 2
Authors:Keusekotten, K, Bade, V.N, Meyer-Teschendorf, K, Sriramachandran, A, Fischer-Schrader, K, Krause, A, Horst, C, Hofmann, K, Dohmen, R.J, Praefcke, G.J.K.
Deposit date:2013-04-25
Release date:2013-11-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Multivalent Interactions of the Sumo-Interaction Motifs in the Ring-Finger Protein 4 (Rnf4) Determine the Specificity for Chains of the Small Ubiquitin-Related Modifier (Sumo).
Biochem.J., 457, 2014
3QBV
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BU of 3qbv by Molmil
Structure of designed orthogonal interaction between CDC42 and nucleotide exchange domains of intersectin
Descriptor: Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, Intersectin-1
Authors:Kapp, G.T, Remenyi, A, Lim, W.A, Kortemme, T.
Deposit date:2011-01-14
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair.
Proc.Natl.Acad.Sci.USA, 109, 2012
3GCG
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BU of 3gcg by Molmil
crystal structure of MAP and CDC42 complex
Descriptor: Cell division control protein 42 homolog, L0028 (Mitochondria associated protein)
Authors:Chai, J, Huang, Z, Feng, Y, Wu, X.
Deposit date:2009-02-22
Release date:2009-07-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics
Nat.Struct.Mol.Biol., 16, 2009
4CR2
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BU of 4cr2 by Molmil
Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
Descriptor: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
Authors:Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F.
Deposit date:2014-02-25
Release date:2014-04-02
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CR4
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BU of 4cr4 by Molmil
Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
Descriptor: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
Authors:Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F.
Deposit date:2014-02-25
Release date:2014-04-02
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CR3
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BU of 4cr3 by Molmil
Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
Descriptor: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
Authors:Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F.
Deposit date:2014-02-25
Release date:2014-04-02
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (9.3 Å)
Cite:Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 111, 2014

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數據於2024-10-02公開中

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