PDB: 263 resultsInfo pagesStatus searchChemie searchBIRD

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7T3B	GATOR1-RAG-RAGULATOR - GAP Complex Descriptor: ALUMINUM FLUORIDE, GATOR complex protein DEPDC5, GATOR complex protein NPRL2, ... Authors: Egri, S.B, Shen, K. Deposit date: 2021-12-07 Release date: 2022-04-06 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism. Mol.Cell, 82, 2022
7T3C	GATOR1-RAG-RAGULATOR - Dual Complex Descriptor: ALUMINUM FLUORIDE, GATOR complex protein DEPDC5, GATOR complex protein NPRL2, ... Authors: Egri, S.B, Shen, K. Deposit date: 2021-12-07 Release date: 2022-04-06 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (4 Å) Cite: Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism. Mol.Cell, 82, 2022
5X6U	Crystal structure of human heteropentameric complex Descriptor: Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... Authors: Yonehara, R, Nada, S, Nakai, T, Nakai, M, Kitamura, A, Ogawa, A, Nakatsumi, H, Nakayama, K.I, Li, S, Standley, D.M, Yamashita, E, Nakagawa, A, Okada, M. Deposit date: 2017-02-23 Release date: 2017-12-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for the assembly of the Ragulator-Rag GTPase complex. Nat Commun, 8, 2017
6NZD	Cryo-EM Structure of the Lysosomal Folliculin Complex (FLCN-FNIP2-RagA-RagC-Ragulator) Descriptor: 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, Folliculin, Folliculin-interacting protein 2, ... Authors: Fromm, S.A, Young, L.N, Hurley, J.H. Deposit date: 2019-02-13 Release date: 2019-11-06 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex. Science, 366, 2019
5Y3A	Crystal structure of Ragulator complex (p18 49-161) Descriptor: Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... Authors: Zhang, T, Ding, J. Deposit date: 2017-07-28 Release date: 2017-12-27 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1. Nat Commun, 8, 2017
5YK3	human Ragulator complex Descriptor: Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... Authors: Wu, G, Mu, Z. Deposit date: 2017-10-12 Release date: 2019-01-23 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (3.01 Å) Cite: Structural insight into the Ragulator complex which anchors mTORC1 to the lysosomal membrane Cell Discov, 3, 2017
7UX2	cryo-EM structure of the Raptor-TFEB-Rag-Ragulator complex Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Cui, Z, Hurley, J. Deposit date: 2022-05-04 Release date: 2022-11-30 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature, 614, 2023
7UXC	cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex with symmetry expansion Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... Authors: Cui, Z, Hurley, J. Deposit date: 2022-05-05 Release date: 2022-11-30 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature, 614, 2023
7UXH	cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... Authors: Cui, Z, Hurley, J. Deposit date: 2022-05-05 Release date: 2022-11-30 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature, 614, 2023
5X6V	Crystal structure of human heteroheptameric complex Descriptor: ACETATE ION, Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, ... Authors: Yonehara, R, Nada, S, Nakai, T, Nakai, M, Kitamura, A, Ogawa, A, Nakatsumi, H, Nakayama, K.I, Li, S, Standley, D.M, Yamashita, E, Nakagawa, A, Okada, M. Deposit date: 2017-02-23 Release date: 2017-12-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Structural basis for the assembly of the Ragulator-Rag GTPase complex. Nat Commun, 8, 2017
5Y39	Crystal structure of Ragulator complex (p18 76-145) Descriptor: Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... Authors: Zhang, T, Ding, J. Deposit date: 2017-07-28 Release date: 2017-12-06 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1 Nat Commun, 8, 2017
6EHR	The crystal structure of the human LAMTOR-RagA CTD-RagC CTD complex Descriptor: Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... Authors: Scheffzek, K, Naschberger, A. Deposit date: 2017-09-14 Release date: 2017-10-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.898 Å) Cite: Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling. Science, 358, 2017
6EHP	The crystal structure of the human LAMTOR complex Descriptor: CHLORIDE ION, Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, ... Authors: Scheffzek, K, Naschberger, A. Deposit date: 2017-09-14 Release date: 2017-10-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling. Science, 358, 2017

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