5X6V

Crystal structure of human heteroheptameric complex

Summary for 5X6V

• Entry DOI: 10.2210/pdb5x6v/pdb
• Related: 5X6U
• Descriptor: Ragulator complex protein LAMTOR3, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR5, ... (10 entities in total)
• Functional Keywords: ragulator rag gtpase complex, scaffold, roadblock, lysosome, mtor signaling, cell growth, protein binding
• Biological source: Homo sapiens (Human); More
• Cellular location: Late endosome membrane ; Peripheral membrane protein ; Cytoplasmic side : Q9UHA4 Q9Y2Q5; Cytoplasm: O43504 Q7L523 Q99K70; Lysosome : Q0VGL1; Late endosome membrane; Lipid-anchor; Cytoplasmic side: Q6IAA8
• Total number of polymer chains: 7
• Total formula weight: 92674.85

Authors

Yonehara, R.,Nada, S.,Nakai, T.,Nakai, M.,Kitamura, A.,Ogawa, A.,Nakatsumi, H.,Nakayama, K.I.,Li, S.,Standley, D.M.,Yamashita, E.,Nakagawa, A.,Okada, M. (deposition date: 2017-02-23, release date: 2017-12-06, Last modification date: 2023-11-22)

• Primary citation: Yonehara, R.,Nada, S.,Nakai, T.,Nakai, M.,Kitamura, A.,Ogawa, A.,Nakatsumi, H.,Nakayama, K.I.,Li, S.,Standley, D.M.,Yamashita, E.,Nakagawa, A.,Okada, M.; Structural basis for the assembly of the Ragulator-Rag GTPase complex.; Nat Commun, 8:1625-1625, 2017; PubMed: 29158492; DOI: 10.1038/s41467-017-01762-3

Experimental method

X-RAY DIFFRACTION (2.02 Å)