PDB: 5725 resultsInfo pagesStatus searchChemie searchBIRD

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7NFO	A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I17C. Descriptor: CC-Type2-(LaId)4-I17C Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFM	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L21K. Descriptor: CC-Type2-(LaId)4-L21K Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFI	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L7Y. Descriptor: CC-Type2-(LaId)4-L7Y Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFP	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I17K Descriptor: CC-Type2-(LaId)4-I17K, GLYCEROL Authors: Burton, A.J, Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFK	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24S. Descriptor: CC-Type2-(LaId)4-I24S, ISOPROPYL ALCOHOL Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFG	A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L14A. Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, CC-Type2-(LaId)4-L14A Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.09 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFH	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(MaId)4. Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CC-Type2-(MaId)4 Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFN	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L21N-I24N. Descriptor: CC-Type2-(LaId)4-L21N-I24N, HEXANE-1,6-DIOL Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
5JI4	Solution structure of the de novo mini protein gEEHE_02 Descriptor: W37 Authors: Buchko, G.W, Bahl, C.D, Pulavarti, S.V, Baker, D, Szyperski, T. Deposit date: 2016-04-21 Release date: 2016-09-28 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Accurate de novo design of hyperstable constrained peptides. Nature, 538, 2016
5JHI	Solution structure of the de novo mini protein gEHE_06 Descriptor: W35 Authors: Buchko, G.W, Bahl, C.D, Gilmore, J.M, Pulavarti, S.V, Baker, D, Szyperski, T. Deposit date: 2016-04-21 Release date: 2016-09-28 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Accurate de novo design of hyperstable constrained peptides. Nature, 538, 2016
4DZM	A de novo designed Coiled Coil CC-Di Descriptor: COILED-COIL PEPTIDE CC-DI Authors: Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. Deposit date: 2012-03-01 Release date: 2012-08-29 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.94 Å) Cite: A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
4DZN	A de novo designed Coiled Coil CC-pIL Descriptor: COILED-COIL PEPTIDE CC-PIL Authors: Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. Deposit date: 2012-03-01 Release date: 2012-08-29 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.59 Å) Cite: A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
4DZL	A de novo designed Coiled Coil CC-Tri Descriptor: COILED-COIL PEPTIDE CC-TRI Authors: Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. Deposit date: 2012-03-01 Release date: 2012-08-29 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
4DZK	A de novo designed Coiled Coil CC-Tri-N13 Descriptor: CHLORIDE ION, COILED-COIL PEPTIDE CC-TRI-N13 Authors: Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. Deposit date: 2012-03-01 Release date: 2012-08-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.79 Å) Cite: A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
1L4X	Octameric de novo designed peptide Descriptor: CHLORIDE ION, MAGNESIUM ION, SIN-ASP-GLU-LEU-GLU-ARG-ALA-ILE-ARG-GLU-LEU-ALA-ALA-ARG-ILE-LYS-NH2 Authors: Meier, M, Lustig, A, Aebi, U, Burkhard, P. Deposit date: 2002-03-06 Release date: 2002-11-13 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (2 Å) Cite: Removing an interhelical salt bridge abolishes coiled-coil formation in a de novo designed peptide J.STRUCT.BIOL., 137, 2002
1IVL	THE DE NOVO DESIGN OF AN ANTIBODY COMBINING SITE: CRYSTALLOGRAPHIC ANALYSIS OF THE VL DOMAIN CONFIRMS THE STRUCTURAL MODEL Descriptor: IGG-KAPPA M29B FV (LIGHT CHAIN), ISOPROPYL ALCOHOL Authors: Essen, L.-O, Skerra, A. Deposit date: 1994-05-04 Release date: 1994-08-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.17 Å) Cite: The de novo design of an antibody combining site. Crystallographic analysis of the VL domain confirms the structural model. J.Mol.Biol., 238, 1994
3RA3	Crystal structure of a section of a de novo design gigaDalton protein fibre Descriptor: SODIUM ION, p1c, p2f Authors: Zaccai, N.R, Sharp, T.H, Bruning, M, Woolfson, D.N, Brady, R.L. Deposit date: 2011-03-27 Release date: 2012-08-08 Last modified: 2013-06-19 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Cryo-transmission electron microscopy structure of a gigadalton peptide fiber of de novo design Proc.Natl.Acad.Sci.USA, 109, 2012
3VJF	Crystal structure of de novo 4-helix bundle protein WA20 Descriptor: POTASSIUM ION, WA20 Authors: Arai, R, Kimura, A, Kobayashi, N, Matsuo, K, Sato, T, Wang, A.F, Platt, J.M, Bradley, L.H, Hecht, M.H. Deposit date: 2011-10-18 Release date: 2012-03-28 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Domain-swapped dimeric structure of a stable and functional de novo four-helix bundle protein, WA20 J.Phys.Chem.B, 116, 2012
8CCR	Crystal structure of the T19D mutant of the de novo diheme binding 4D2 Descriptor: (2S)-2-hydroxybutanedioic acid, 4D2 (mutant T19D), CHLORIDE ION, ... Authors: Barringer, R, Anderson, R. Deposit date: 2023-01-27 Release date: 2023-08-09 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.1 Å) Cite: An expandable, modular de novo protein platform for precision redox engineering. Proc.Natl.Acad.Sci.USA, 120, 2023
3B83	Computer-Based Redesign of a beta Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo beta Sheet Design. Descriptor: TEN-D3 Authors: Hu, X, Ke, H, Kuhlman, B. Deposit date: 2007-10-31 Release date: 2008-11-04 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Computer-Based Redesign of a beta Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo beta Sheet Design. Structure, 16, 2008
3UD6	Structural analyses of covalent enzyme-substrate analogue complexes reveal strengths and limitations of de novo enzyme design Descriptor: 1-(6-METHOXYNAPHTHALEN-2-YL)BUTANE-1,3-DIONE, RETRO-ALDOLASE, SULFATE ION Authors: Baker, D, Stoddard, B.L, Althoff, E.A, Wang, L, Jiang, L, Moody, J, Bolduc, J, Lassila, J, Hilvert, D. Deposit date: 2011-10-27 Release date: 2011-11-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.091 Å) Cite: Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design. J.Mol.Biol., 415, 2012
6XXV	Crystal Structure of a computationally designed Immunogen S2_1.2 in complex with its elicited antibody C57 Descriptor: Antibody C57, Heavy Chain, Light Chain, ... Authors: Yang, C, Sesterhenn, F, Correia, B.E, Pojer, F. Deposit date: 2020-01-28 Release date: 2020-04-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.20116425 Å) Cite: De novo protein design enables the precise induction of RSV-neutralizing antibodies. Science, 368, 2020
8ETQ	Designed pentafoil knot protein folded into a trefoil knot Descriptor: k-cTRP5 Authors: Doyle, L.A, Kibler, R.D, Bradley, P, Stoddard, B.L. Deposit date: 2022-10-17 Release date: 2023-10-25 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.42 Å) Cite: De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
7SQ4	Designed trefoil knot protein, variant 2 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Designed trefoil knot protein, variant 2, ... Authors: Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P. Deposit date: 2021-11-04 Release date: 2022-06-29 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.493 Å) Cite: De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
7SQ3	Designed trefoil knot protein, variant 1 Descriptor: CHLORIDE ION, Designed trefoil knot protein, variant 1, ... Authors: Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P. Deposit date: 2021-11-04 Release date: 2022-06-29 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.453 Å) Cite: De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023

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