6M2K
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![BU of 6m2k by Molmil](/molmil-images/mine/6m2k) | Uncommon structural features of rabbit MHC class I (RLA-A1) complexed with rabbit haemorrhagic disease virus (RHDV) derived peptide, VP60-10 | Descriptor: | Beta-2-microglobulin, RLA class I histocompatibility antigen, alpha chain 19-1, ... | Authors: | Zhang, Q.X, Liu, K.F, Yue, C, Zhang, D, Lu, D, Xiao, W.L, Liu, P.P, Zhao, Y.Z, Gao, G.L, Ding, C.M, Lyu, J.X, Liu, W.J. | Deposit date: | 2020-02-27 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Strict Assembly Restriction of Peptides from Rabbit Hemorrhagic Disease Virus Presented by Rabbit Major Histocompatibility Complex Class I Molecule RLA-A1. J.Virol., 94, 2020
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5VZ5
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![BU of 5vz5 by Molmil](/molmil-images/mine/5vz5) | Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501 | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | Authors: | Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G. | Deposit date: | 2017-05-26 | Release date: | 2018-03-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5901 Å) | Cite: | A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations. Front Immunol, 9, 2018
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8DVG
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![BU of 8dvg by Molmil](/molmil-images/mine/8dvg) | Structure of KRAS WT(7-16)-HLA-A*03:01 | Descriptor: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, HLA class I histocompatibility antigen, ... | Authors: | Wright, K.M, Miller, M, Gabelli, S.B. | Deposit date: | 2022-07-28 | Release date: | 2023-07-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.594 Å) | Cite: | Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen. Nat Commun, 14, 2023
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8ZV9
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![BU of 8zv9 by Molmil](/molmil-images/mine/8zv9) | Complex structure of HLA2402 with recognizing SARS-CoV-2 Y453F epitope NYNYLFRLF | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, MHC class I antigen, ... | Authors: | Deng, S.S, Jin, T.C, Xu, Z.H, Wang, M.H. | Deposit date: | 2024-06-11 | Release date: | 2024-08-21 | Last modified: | 2024-08-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into immune escape at killer T cell epitope by SARS-CoV-2 Spike Y453F variants. J.Biol.Chem., 300, 2024
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3L3K
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![BU of 3l3k by Molmil](/molmil-images/mine/3l3k) | Crystal structure of HLA-B*4402 in complex with the R5A/F7A double mutant of a self-peptide derived from DPA*0201 | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | Authors: | Theodossis, A, Ely, L.K, Rossjohn, J. | Deposit date: | 2009-12-17 | Release date: | 2010-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition Proc.Natl.Acad.Sci.USA, 107, 2010
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6AVG
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![BU of 6avg by Molmil](/molmil-images/mine/6avg) | Crystal structure of the KFJ37 TCR-NY-ESO-1-HLA-B*07:02 complex | Descriptor: | ALA-PRO-ARG-GLY-PRO-HIS-GLY-GLY-ALA-ALA-SER-GLY-LEU, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Gully, B.S, Gras, S, Rossjohn, J. | Deposit date: | 2017-09-02 | Release date: | 2018-02-28 | Last modified: | 2018-03-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide. Nat Commun, 9, 2018
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7RTR
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![BU of 7rtr by Molmil](/molmil-images/mine/7rtr) | |
7N2N
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![BU of 7n2n by Molmil](/molmil-images/mine/7n2n) | TCR-antigen complex AS4.2-PRPF3-HLA*B27 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Yang, X, Jude, K.M, Garcia, K.C. | Deposit date: | 2021-05-29 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
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1HHG
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![BU of 1hhg by Molmil](/molmil-images/mine/1hhg) | THE ANTIGENIC IDENTITY OF PEPTIDE(SLASH)MHC COMPLEXES: A COMPARISON OF THE CONFORMATION OF FIVE PEPTIDES PRESENTED BY HLA-A2 | Descriptor: | BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), HIV-1 GP120 ENVELOPE PROTEIN (RESIDUES 195-207) | Authors: | Madden, D.R, Garboczi, D.N, Wiley, D.C. | Deposit date: | 1993-06-30 | Release date: | 1993-10-31 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2. Cell(Cambridge,Mass.), 75, 1993
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4KDT
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![BU of 4kdt by Molmil](/molmil-images/mine/4kdt) | Structure of an early native-like intermediate of beta2-microglobulin amyloidosis | Descriptor: | Beta-2-microglobulin, GLYCEROL, Nanobody24, ... | Authors: | Vanderhaegen, S, Fislage, M, Pardon, E, Versees, W, Steyaert, J. | Deposit date: | 2013-04-25 | Release date: | 2013-08-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of an early native-like intermediate of beta 2-microglobulin amyloidogenesis. Protein Sci., 22, 2013
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2XPG
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![BU of 2xpg by Molmil](/molmil-images/mine/2xpg) | Crystal structure of a MHC class I-peptide complex | Descriptor: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-3 ALPHA CHAIN, ... | Authors: | McMahon, R.M, Friis, L, Siebold, C, Friese, M.A, Fugger, L, Jones, E.Y. | Deposit date: | 2010-08-26 | Release date: | 2011-04-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Hla-A0301 in Complex with a Peptide of Proteolipid Protein: Insights Into the Role of Hla-A Alleles in Susceptibility to Multiple Sclerosis Acta Crystallogr.,Sect.D, 67, 2011
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3UTT
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![BU of 3utt by Molmil](/molmil-images/mine/3utt) | 1E6-A*0201-ALWGPDPAAA Complex, Triclinic | Descriptor: | 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, Beta-2-microglobulin, ... | Authors: | Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M, Rossjohn, J, Gras, S. | Deposit date: | 2011-11-26 | Release date: | 2012-01-25 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes. Nat.Immunol., 13, 2012
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1A6Z
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![BU of 1a6z by Molmil](/molmil-images/mine/1a6z) | HFE (HUMAN) HEMOCHROMATOSIS PROTEIN | Descriptor: | BETA-2-MICROGLOBULIN, HFE | Authors: | Lebron, J.A, Bennett, M.J, Vaughn, D.E, Chirino, A.J, Snow, P.M, Mintier, G.A, Feder, J.N, Bjorkman, P.J. | Deposit date: | 1998-03-04 | Release date: | 1999-03-23 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor. Cell(Cambridge,Mass.), 93, 1998
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5VGE
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![BU of 5vge by Molmil](/molmil-images/mine/5vge) | Crystal structure of HLA-C*07:02 in complex with RYR peptide | Descriptor: | ARG-TYR-ARG-PRO-GLY-THR-VAL-ALA-LEU, Beta-2-microglobulin, ZINC ION, ... | Authors: | Mobbs, J.I, Vivian, J.P, Gras, S, Rossjohn, J. | Deposit date: | 2017-04-11 | Release date: | 2017-06-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and regulatory diversity shape HLA-C protein expression levels. Nat Commun, 8, 2017
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3KPR
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![BU of 3kpr by Molmil](/molmil-images/mine/3kpr) | Crystal Structure of the LC13 TCR in complex with HLA B*4405 bound to EEYLKAWTF a mimotope | Descriptor: | Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ... | Authors: | Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. | Deposit date: | 2009-11-16 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | T cell allorecognition via molecular mimicry. Immunity, 31, 2009
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3HLA
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![BU of 3hla by Molmil](/molmil-images/mine/3hla) | HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN A2.1 | Descriptor: | BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A2.1) (ALPHA CHAIN) | Authors: | Saper, M.A, Bjorkman, P.J, Wiley, D.C. | Deposit date: | 1989-10-06 | Release date: | 1990-04-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution. J.Mol.Biol., 219, 1991
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3M17
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![BU of 3m17 by Molmil](/molmil-images/mine/3m17) | Crystal structure of human FcRn with a monomeric peptide inhibitor | Descriptor: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51, monomeric peptide inhibitor | Authors: | Mezo, A.R, Sridhar, V, Badger, J, Sakorafas, P, Nienaber, V. | Deposit date: | 2010-03-04 | Release date: | 2010-06-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | X-ray crystal structures of monomeric and dimeric peptide inhibitors in complex with the human neonatal Fc receptor, FcRn. J.Biol.Chem., 285, 2010
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1AO7
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![BU of 1ao7 by Molmil](/molmil-images/mine/1ao7) | COMPLEX BETWEEN HUMAN T-CELL RECEPTOR, VIRAL PEPTIDE (TAX), AND HLA-A 0201 | Descriptor: | BETA-2 MICROGLOBULIN, ETHYL MERCURY ION, HLA-A 0201, ... | Authors: | Garboczi, D.N, Ghosh, P, Utz, U, Fan, Q.R, Biddison, W.E, Wiley, D.C. | Deposit date: | 1997-07-21 | Release date: | 1997-09-17 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature, 384, 1996
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2ESV
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![BU of 2esv by Molmil](/molmil-images/mine/2esv) | Structure of the HLA-E-VMAPRTLIL/KK50.4 TCR complex | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ... | Authors: | Hoare, H.L, Rossjohn, J. | Deposit date: | 2005-10-27 | Release date: | 2006-03-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for a major histocompatibility complex class Ib-restricted T cell response Nat.Immunol., 7, 2006
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2HLA
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![BU of 2hla by Molmil](/molmil-images/mine/2hla) | |
3TO2
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![BU of 3to2 by Molmil](/molmil-images/mine/3to2) | Structure of HLA-A*0201 complexed with peptide Md3-C9 derived from a clustering region of restricted cytotoxic T lymphocyte epitope from SARS-CoV M protein | Descriptor: | Beta-2-microglobulin, MHC class I antigen, Md3-C9 peptide derived from Membrane glycoprotein | Authors: | Liu, J, Qi, J, Gao, F, Yan, J, Gao, G.F. | Deposit date: | 2011-09-03 | Release date: | 2012-08-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Functional and Structural Definition of a Clustering Region of HLA-A2-restricted Cytotoxic T Lymphocyte Epitopes Sci.Technology Rev., 29, 2011
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8GON
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![BU of 8gon by Molmil](/molmil-images/mine/8gon) | |
3W0W
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![BU of 3w0w by Molmil](/molmil-images/mine/3w0w) | The complex between T36-5 TCR and HLA-A24 bound to HIV-1 Nef134-10(2F) peptide in space group P212121 | Descriptor: | 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A. | Deposit date: | 2012-11-05 | Release date: | 2013-11-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.603 Å) | Cite: | Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection SCI REP, 3, 2013
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6VRM
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![BU of 6vrm by Molmil](/molmil-images/mine/6vrm) | T cell receptor-p53-HLA-A2 complex | Descriptor: | Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen, ... | Authors: | Wu, D, Gallagher, D.T, Gowthaman, R, Pierce, B.G, Mariuzza, R.A. | Deposit date: | 2020-02-08 | Release date: | 2020-06-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen. Nat Commun, 11, 2020
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3VXO
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![BU of 3vxo by Molmil](/molmil-images/mine/3vxo) | HLA-A24 in complex with HIV-1 Nef134-10(2F) | Descriptor: | 10-mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A. | Deposit date: | 2012-09-20 | Release date: | 2013-10-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection SCI REP, 3, 2013
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