8HSP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hsp by Molmil](/molmil-images/mine/8hsp) | E. coli 70S ribosome complexed with tRNA_Ile2 bearing L34 and t6A37 in classical state | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-12-20 | Release date: | 2024-04-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.32 Å) | Cite: | Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 31, 2024
|
|
8P17
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p17 by Molmil](/molmil-images/mine/8p17) | E167K RF2 on E. coli 70S release complex with UGG (Structure II) | Descriptor: | 1,4-DIAMINOBUTANE, 16S RNA, 23S rRNA, ... | Authors: | Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. | Deposit date: | 2023-05-11 | Release date: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of
RF1 in bacteria To Be Published
|
|
8IP9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ip9 by Molmil](/molmil-images/mine/8ip9) | Wheat 40S ribosome in complex with a tRNAi | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S23, 40S ribosomal protein eS1, ... | Authors: | Yokoyama, T, Tanaka, M, Saito, H, Nishimoto, M, Tsuda, K, Sotta, N, Shigematsu, H, Shirouzu, M, Iwasaki, S, Ito, T, Fujiwara, T. | Deposit date: | 2023-03-14 | Release date: | 2024-02-21 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1. Nat.Chem.Biol., 20, 2024
|
|
8IPA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ipa by Molmil](/molmil-images/mine/8ipa) | Wheat 80S ribosome stalled on AUG-Stop boron dependently with cycloheximide | Descriptor: | 18S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, 40S ribosomal protein eL8, ... | Authors: | Yokoyama, T, Tanaka, M, Saito, H, Nishimoto, M, Tsuda, K, Sotta, N, Shigematsu, H, Shirouzu, M, Iwasaki, S, Ito, T, Fujiwara, T. | Deposit date: | 2023-03-14 | Release date: | 2024-02-21 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1. Nat.Chem.Biol., 20, 2024
|
|
8IPB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ipb by Molmil](/molmil-images/mine/8ipb) | Wheat 80S ribosome pausing on AUG-Stop with cycloheximide | Descriptor: | 18S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, 40S ribosomal protein eL8, ... | Authors: | Yokoyama, T, Tanaka, M, Saito, H, Nishimoto, M, Tsuda, K, Sotta, N, Shigematsu, H, Shirouzu, M, Iwasaki, S, Ito, T, Fujiwara, T. | Deposit date: | 2023-03-14 | Release date: | 2024-02-21 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1. Nat.Chem.Biol., 20, 2024
|
|
7UW1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uw1 by Molmil](/molmil-images/mine/7uw1) | A. baumannii 70S ribosome-Streptothricin-D complex | Descriptor: | 16s Ribosomal RNA, 23s ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Morgan, C.E, Yu, E.W. | Deposit date: | 2022-05-02 | Release date: | 2023-04-19 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.21 Å) | Cite: | Streptothricin F is a bactericidal antibiotic effective against highly drug-resistant gram-negative bacteria that interacts with the 30S subunit of the 70S ribosome. Plos Biol., 21, 2023
|
|
8PVA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pva by Molmil](/molmil-images/mine/8pva) | Structure of bacterial ribosome determined by cryoEM at 100 keV | Descriptor: | 16S rRNA, 23S rRNA, 50S ribosomal protein L14, ... | Authors: | McMullan, G, Naydenova, K, Mihaylov, D, Peet, M.J, Wilson, H, Yamashita, K, Dickerson, J.L, Chen, S, Cannone, G, Lee, Y, Hutchings, K.A, Gittins, O, Sobhy, M, Wells, T, El-Gomati, M.M, Dalby, J, Meffert, M, Schulze-Briese, C, Henderson, R, Russo, C.J. | Deposit date: | 2023-07-17 | Release date: | 2023-11-29 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure determination by cryoEM at 100 keV. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8OO0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8oo0 by Molmil](/molmil-images/mine/8oo0) | Chaetomium thermophilum Methionine Aminopeptidase 2 autoproteolysis product at the 80S ribosome | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S0, ... | Authors: | Klein, M.A, Wild, K, Kisonaite, M, Sinning, I. | Deposit date: | 2023-04-04 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome. Nat Commun, 15, 2024
|
|
6FKR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fkr by Molmil](/molmil-images/mine/6fkr) | Crystal structure of the dolphin proline-rich antimicrobial peptide Tur1A bound to the Thermus thermophilus 70S ribosome | Descriptor: | 16 ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Mardirossian, M, Perebaskine, N, Benincasa, M, Gambato, S, Hofmann, S, Huter, P, Muller, C, Hilpert, K, Innis, C.A, Tossi, A, Wilson, D.N. | Deposit date: | 2018-01-24 | Release date: | 2018-03-28 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome. Cell Chem Biol, 25, 2018
|
|
8P5D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p5d by Molmil](/molmil-images/mine/8p5d) | Spraguea lophii ribosome in the closed conformation by cryo sub tomogram averaging | Descriptor: | 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S10, ... | Authors: | Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B. | Deposit date: | 2023-05-23 | Release date: | 2023-06-21 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (10.8 Å) | Cite: | CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state. Nat Microbiol, 8, 2023
|
|
8P60
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p60 by Molmil](/molmil-images/mine/8p60) | Spraguea lophii ribosome dimer | Descriptor: | 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | Authors: | Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B. | Deposit date: | 2023-05-24 | Release date: | 2023-06-21 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (14.3 Å) | Cite: | CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state. Nat Microbiol, 8, 2023
|
|
6FXC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fxc by Molmil](/molmil-images/mine/6fxc) | The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Matzov, D, Aibara, S, Zimmerman, E, Bashan, A, Kidmose, R, Amunts, A, Yonath, A. | Deposit date: | 2018-03-08 | Release date: | 2018-03-21 | Last modified: | 2018-11-21 | Method: | ELECTRON MICROSCOPY (6.76 Å) | Cite: | The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus. Nat Commun, 8, 2017
|
|
6G53
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g53 by Molmil](/molmil-images/mine/6g53) | Cryo-EM structure of a late human pre-40S ribosomal subunit - State E | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | Deposit date: | 2018-03-28 | Release date: | 2018-06-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
|
|
6GSN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gsn by Molmil](/molmil-images/mine/6gsn) | |
6GXP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gxp by Molmil](/molmil-images/mine/6gxp) | Cryo-EM structure of a rotated E. coli 70S ribosome in complex with RF3-GDPCP(RF3-only) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N. | Deposit date: | 2018-06-27 | Release date: | 2018-08-15 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1. Nat Commun, 9, 2018
|
|
8Q5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8q5i by Molmil](/molmil-images/mine/8q5i) | Structure of Candida albicans 80S ribosome in complex with cephaeline | Descriptor: | 18S ribosomal RNA, 25S rRNA, 40S ribosomal protein S0, ... | Authors: | Kolosova, O, Zgadzay, Y, Stetsenko, A, Atamas, A, Guskov, A, Yusupov, M. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.45 Å) | Cite: | Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy Biopolym Cell, 2023
|
|
8PPL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ppl by Molmil](/molmil-images/mine/8ppl) | MERS-CoV Nsp1 bound to the human 43S pre-initiation complex | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N. | Deposit date: | 2023-07-07 | Release date: | 2023-10-18 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol.Cell, 83, 2023
|
|
8PPK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ppk by Molmil](/molmil-images/mine/8ppk) | Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N. | Deposit date: | 2023-07-07 | Release date: | 2023-10-18 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol.Cell, 83, 2023
|
|
6FYX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fyx by Molmil](/molmil-images/mine/6fyx) | Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | Authors: | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2018-03-12 | Release date: | 2018-12-05 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition. Elife, 7, 2018
|
|
8P2K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p2k by Molmil](/molmil-images/mine/8p2k) | Ternary complex of translating ribosome, NAC and METAP1 | Descriptor: | 18s rRNA, 28S rRNA, 40S ribosomal protein S11, ... | Authors: | Jia, M, Jaskolowski, M, Scaiola, A, Jomaa, A, Ban, N. | Deposit date: | 2023-05-16 | Release date: | 2023-07-19 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | NAC controls cotranslational N-terminal methionine excision in eukaryotes. Science, 380, 2023
|
|
8OVE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ove by Molmil](/molmil-images/mine/8ove) | |
8OVA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ova by Molmil](/molmil-images/mine/8ova) | |
6GQ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gq1 by Molmil](/molmil-images/mine/6gq1) | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | Authors: | Pellegrino, S, Demeshkina, N, Mancera-Martinez, E, Melnikov, S, Simonetti, A, Myasnikov, A, Yusupov, M, Yusupova, G, Hashem, Y. | Deposit date: | 2018-06-07 | Release date: | 2018-07-11 | Last modified: | 2018-08-08 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance. J. Mol. Biol., 430, 2018
|
|
6GXO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gxo by Molmil](/molmil-images/mine/6gxo) | Cryo-EM structure of a rotated E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and P/E-tRNA (State IV) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N. | Deposit date: | 2018-06-27 | Release date: | 2018-08-15 | Last modified: | 2018-10-24 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1. Nat Commun, 9, 2018
|
|
8IFC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ifc by Molmil](/molmil-images/mine/8ifc) | Arbekacin-bound E.coli 70S ribosome in the PURE system | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | Deposit date: | 2023-02-17 | Release date: | 2024-02-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
|
|