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PDB: 1371 results

5GNL
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BU of 5gnl by Molmil
Cytochrome P450 Vdh (CYP107BR1) F106V mutant
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, PROTOPORPHYRIN IX CONTAINING FE, Vitamin D(3) 25-hydroxylase
Authors:Yasutake, Y, Tamura, T.
Deposit date:2016-07-22
Release date:2017-05-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural insights into the mechanism of the drastic changes in enzymatic activity of the cytochrome P450 vitamin D3 hydroxylase (CYP107BR1) caused by a mutation distant from the active site
Acta Crystallogr F Struct Biol Commun, 73, 2017
5FOI
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BU of 5foi by Molmil
Crystal structure of mycinamicin VIII C21 methyl hydroxylase MycCI from Micromonospora griseorubida bound to mycinamicin VIII
Descriptor: GLYCEROL, MYCINAMICIN VIII C21 METHYL HYDROXYLASE, Mycinamicin VIII, ...
Authors:Demars, M, Sheng, F, Podust, L.M, Sherman, D.H.
Deposit date:2015-11-22
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Biochemical and Structural Characterization of Mycci, a Versatile P450 Biocatalyst from the Mycinamicin Biosynthetic Pathway.
Acs Chem.Biol., 11, 2016
2BVJ
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BU of 2bvj by Molmil
Ligand-free structure of cytochrome P450 PikC (CYP107L1)
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BETA-MERCAPTOETHANOL, CYTOCHROME P450 MONOOXYGENASE, ...
Authors:Sherman, D.H, Li, S, Yermalitskaya, L.V, Kim, Y, Smith, J.A, Waterman, M.R, Podust, L.M.
Deposit date:2005-06-28
Release date:2006-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structural Basis for Substrate Anchoring, Active Site Selectivity, and Product Formation by P450 Pikc from Streptomyces Venezuelae.
J.Biol.Chem., 281, 2006
1IO9
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BU of 1io9 by Molmil
THERMOPHILIC CYTOCHROME P450 (CYP119) FROM SULFOLOBUS SOLFATARICUS: HIGH RESOLUTION STRUCTURAL ORIGIN OF ITS THERMOSTABILITY AND FUNCTIONAL PROPERTIES
Descriptor: CYTOCHROME P450 CYP119, PROTOPORPHYRIN IX CONTAINING FE
Authors:Park, S.-Y, Yamane, K, Adachi, S, Shiro, Y, Sligar, S.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2001-02-08
Release date:2001-03-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties.
J.Inorg.Biochem., 91, 2002
2BMH
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BU of 2bmh by Molmil
MODELING PROTEIN-SUBSTRATE INTERACTIONS IN THE HEME DOMAIN OF CYTOCHROME P450BM-3
Descriptor: CYTOCHROME P450 BM-3, PROTOPORPHYRIN IX CONTAINING FE
Authors:Li, H, Poulos, T.L.
Deposit date:1994-05-17
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Modeling protein-substrate interactions in the heme domain of cytochrome P450(BM-3).
Acta Crystallogr.,Sect.D, 51, 1995
5XHJ
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BU of 5xhj by Molmil
Crystal Structure of P450BM3 with 5-Cyclohexylvaleroyl-L-Tryptophan
Descriptor: 5-cyclohexylpentanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Suzuki, K, Shoji, O, Stanfield, J.K, Kasai, C, Sugimoto, H, Shiro, Y, Watanabe, Y.
Deposit date:2017-04-21
Release date:2017-12-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Control of stereoselectivity of benzylic hydroxylation catalysed by wild-type cytochrome P450BM3 using decoy molecules
CATALYSIS SCIENCE AND TECHNOLOGY, 7, 2017
1IWK
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BU of 1iwk by Molmil
Putidaredoxin-Binding Stablilizes an Active Conformer of Cytochrome P450cam in its Reduced State; Crystal Structure of Mutant(112K) Cytochrome P450cam
Descriptor: CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE
Authors:Nagano, S, Shimada, H, Tarumi, A, Hishiki, T, Kimata-Ariga, Y, Egawa, T, Park, S.-Y, Adachi, S, Shiro, Y, Ishimura, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-05-15
Release date:2002-06-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Infrared spectroscopic and mutational studies on putidaredoxin-induced conformational changes in ferrous CO-P450cam
Biochemistry, 42, 2003
1Z8O
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BU of 1z8o by Molmil
Ferrous dioxygen complex of the wild-type cytochrome P450eryF
Descriptor: 6-DEOXYERYTHRONOLIDE B, 6-deoxyerythronolide B hydroxylase, OXYGEN MOLECULE, ...
Authors:Nagano, S, Cupp-Vickery, J.R, Poulos, T.L.
Deposit date:2005-03-31
Release date:2005-04-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of the ferrous dioxygen complex of wild-type cytochrome P450eryF and its mutants, A245S and A245T: investigation of the proton transfer system in P450eryF.
J.Biol.Chem., 280, 2005
1Z11
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BU of 1z11 by Molmil
Crystal Structure of Human Microsomal P450 2A6 with Methoxsalen Bound
Descriptor: METHOXSALEN, PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450, ...
Authors:Yano, J.K, Hsu, M.H, Griffin, K.J, Stout, C.D, Johnson, E.F.
Deposit date:2005-03-02
Release date:2005-08-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen
Nat.Struct.Mol.Biol., 12, 2005
5XW2
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BU of 5xw2 by Molmil
Crystal structure of the Hydroxylase HmtN in C 1 2 1 crystal form
Descriptor: Cytochrome P450 107B1 (P450CVIIB1), GLYCEROL, MAGNESIUM ION, ...
Authors:Zhang, H.D, Zhang, H.J.
Deposit date:2017-06-29
Release date:2018-04-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.298 Å)
Cite:Molecular characterization of the hydroxylase HmtN at 1.3 angstrom resolution.
Biochem. Biophys. Res. Commun., 2017
5XXI
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BU of 5xxi by Molmil
Crystal structure of CYP2C9 in complex with multiple losartan molecules
Descriptor: Cytochrome P450 2C9, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Maekawa, K, Adachi, M, Shah, M.B.
Deposit date:2017-07-04
Release date:2017-10-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9
Biochemistry, 56, 2017
2VE4
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BU of 2ve4 by Molmil
Substrate free cyanobacterial CYP120A1
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 120
Authors:Kuhnel, K, Ke, N, Sligar, S.G, Schuler, M.A, Schlichting, I.
Deposit date:2007-10-16
Release date:2008-04-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Substrate-Free and Retinoic Acid-Bound Cyanobacterial Cytochrome P450 Cyp120A1.
Biochemistry, 47, 2008
2UUQ
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BU of 2uuq by Molmil
Crystal structure of CYP130 from Mycobacterium tuberculosis in the ligand-free form
Descriptor: CYTOCHROME P450 130, ISOPROPYL ALCOHOL, PROTOPORPHYRIN IX CONTAINING FE
Authors:Podust, L.M, Ortiz de Montellano, P.R.
Deposit date:2007-03-07
Release date:2007-12-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Mycobacterium Tuberculosis Cyp130:Crystal Mycobacterium Tuberculosis Cyp130: Crystal Structure, Biophysical Characterization, and Interactions with Antifungal Azole Drugs.
J.Biol.Chem., 283, 2008
1GEM
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BU of 1gem by Molmil
STRUCTURAL CHARACTERIZATION OF N-BUTYL-ISOCYANIDE COMPLEXES OF CYTOCHROMES P450NOR AND P450CAM
Descriptor: CYTOCHROME P450CAM, N-BUTYL ISOCYANIDE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Lee, D.-S, Park, S.-Y, Yamane, K, Shiro, Y.
Deposit date:2000-11-13
Release date:2000-12-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural characterization of n-butyl-isocyanide complexes of cytochromes P450nor and P450cam.
Biochemistry, 40, 2001
2Q6N
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BU of 2q6n by Molmil
Structure of Cytochrome P450 2B4 with Bound 1-(4-cholorophenyl)imidazole
Descriptor: 1-(4-CHLOROPHENYL)-1H-IMIDAZOLE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE
Authors:Zhao, Y, Sun, L, Muralidhara, B.K, Kumar, S, White, M.A, Stout, C.D, Halpert, J.R.
Deposit date:2007-06-05
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and thermodynamic consequences of 1-(4-chlorophenyl)imidazole binding to cytochrome P450 2B4.
Biochemistry, 46, 2007
1GED
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BU of 1ged by Molmil
A positive charge route for the access of nadh to heme formed in the distal heme pocket of cytochrome p450nor
Descriptor: BROMIDE ION, CYTOCHROME P450 55A1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Kudo, T, Takaya, N, Park, S.-Y, Shiro, Y, Shoun, H.
Deposit date:2000-11-02
Release date:2000-11-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:A positively charged cluster formed in the heme-distal pocket of cytochrome P450nor is essential for interaction with NADH
J.Biol.Chem., 276, 2001
2UVN
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BU of 2uvn by Molmil
Crystal structure of econazole-bound CYP130 from Mycobacterium tuberculosis
Descriptor: 1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE, CYTOCHROME P450 130, FLUORIDE ION, ...
Authors:Podust, L.M, Ortiz de Montellano, P.R.
Deposit date:2007-03-12
Release date:2007-12-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mycobacterium Tuberculosis Cyp130: Crystal Structure, Biophysical Characterization, and Interactions with Antifungal Azole Drugs
J.Biol.Chem., 283, 2008
1GEB
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BU of 1geb by Molmil
X-RAY CRYSTAL STRUCTURE AND CATALYTIC PROPERTIES OF THR252ILE MUTANT OF CYTOCHROME P450CAM
Descriptor: CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE
Authors:Hishiki, T, Shimada, H, Nagano, S, Park, S.-Y, Ishimura, Y.
Deposit date:2000-11-01
Release date:2000-11-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:X-ray crystal structure and catalytic properties of Thr252Ile mutant of cytochrome P450cam: roles of Thr252 and water in the active center.
J.Biochem., 128, 2000
2CP4
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BU of 2cp4 by Molmil
CRYSTAL STRUCTURE OF THE CYTOCHROME P450-CAM ACTIVE SITE MUTANT THR252ALA
Descriptor: CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE
Authors:Raag, R, Poulos, T.L.
Deposit date:1991-06-04
Release date:1993-01-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala.
Biochemistry, 30, 1991
1IZO
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BU of 1izo by Molmil
Cytochrome P450 BS beta Complexed with Fatty Acid
Descriptor: Cytochrome P450 152A1, PALMITOLEIC ACID, PROTOPORPHYRIN IX CONTAINING FE
Authors:Lee, D.S, Yamada, A, Sugimoto, H, Matsunaga, I, Ogura, H, Ichihara, K, Adachi, S, Park, S.Y, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-10-10
Release date:2003-03-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Substrate Recognition and Molecular Mechanism of Fatty Acid Hydroxylation by Cytochrome P450 from Bacillus subtilis. CRYSTALLOGRAPHIC, SPECTROSCOPIC, AND MUTATIONAL STUDIES.
J.Biol.Chem., 278, 2003
2A1N
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BU of 2a1n by Molmil
Crystal structure of ferrous dioxygen complex of D251N cytochrome P450cam
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ...
Authors:Nagano, S, Poulos, T.L.
Deposit date:2005-06-20
Release date:2005-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic study on the dioxygen complex of wild-type and mutant cytochrome P450cam. Implications for the dioxygen activation mechanism
J.Biol.Chem., 280, 2005
1IO7
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BU of 1io7 by Molmil
THERMOPHILIC CYTOCHROME P450 (CYP119) FROM SULFOLOBUS SOLFATARICUS: HIGH RESOLUTION STRUCTURAL ORIGIN OF ITS THERMOSTABILITY AND FUNCTIONAL PROPERTIES
Descriptor: CYTOCHROME P450 CYP119, PROTOPORPHYRIN IX CONTAINING FE
Authors:Park, S.-Y, Yamane, K, Adachi, S, Shiro, Y, Sligar, S.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2001-02-08
Release date:2001-02-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties.
J.Inorg.Biochem., 91, 2002
2D09
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BU of 2d09 by Molmil
A Role for Active Site Water Molecules and Hydroxyl Groups of Substrate for Oxygen Activation in Cytochrome P450 158A2
Descriptor: FLAVIOLIN, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Zhao, B, Waterman, M.R.
Deposit date:2005-07-30
Release date:2005-10-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of active site water molecules and substrate hydroxyl groups in oxygen activation by cytochrome P450 158A2: a new mechanism of proton transfer
J.Biol.Chem., 280, 2005
2V0M
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BU of 2v0m by Molmil
Crystal structure of human P450 3A4 in complex with ketoconazole
Descriptor: 1-ACETYL-4-(4-{[(2S,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZINE, CYTOCHROME P450 3A4, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sjogren, T, Ekroos, M.
Deposit date:2007-05-15
Release date:2007-06-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Ligand Promiscuity in Cytochrome P450 3A4
Proc.Natl.Acad.Sci.USA, 103, 2006
1JFB
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BU of 1jfb by Molmil
X-ray structure of nitric oxide reductase (cytochrome P450nor) in the ferric resting state at atomic resolution
Descriptor: GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, nitric-oxide reductase cytochrome P450 55A1
Authors:Shimizu, H, Adachi, S, Park, S.Y, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2001-06-20
Release date:2001-12-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:X-ray structure of nitric oxide reductase (cytochrome P450nor) at atomic resolution.
Acta Crystallogr.,Sect.D, 58, 2002

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數據於2024-06-26公開中

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