2UVN

Crystal structure of econazole-bound CYP130 from Mycobacterium tuberculosis

Summary for 2UVN

• Entry DOI: 10.2210/pdb2uvn/pdb
• Related: 2UUQ
• Descriptor: CYTOCHROME P450 130, PROTOPORPHYRIN IX CONTAINING FE, 1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE, ... (6 entities in total)
• Functional Keywords: iron, heme, monooxygenase, metal-binding, oxidoreductase
• Biological source: MYCOBACTERIUM TUBERCULOSIS
• Total number of polymer chains: 2
• Total formula weight: 94320.08

Authors

Podust, L.M.,Ortiz de Montellano, P.R. (deposition date: 2007-03-12, release date: 2007-12-18, Last modification date: 2023-12-13)

• Primary citation: Ouellet, H.,Podust, L.M.,Ortiz de Montellano, P.R.; Mycobacterium Tuberculosis Cyp130: Crystal Structure, Biophysical Characterization, and Interactions with Antifungal Azole Drugs; J.Biol.Chem., 283:5069-, 2008; PubMed: 18089574; DOI: 10.1074/JBC.M708734200

Experimental method

X-RAY DIFFRACTION (3 Å)