2UVN
Crystal structure of econazole-bound CYP130 from Mycobacterium tuberculosis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CYTOCHROME P450 130 | polymer | 414 | 45836.8 | 2 | UniProt (Q11062) Pfam (PF00067) UniProt (by SIFTS) (P9WPN5) | MYCOBACTERIUM TUBERCULOSIS | CYP130 |
| 2 | C, L (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, M (A, B) | 1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE | non-polymer | 381.7 | 2 | Chemie (ECN) | |||
| 4 | E, F, G, K, N... (A, B) | FLUORIDE ION | non-polymer | 19.0 | 14 | Chemie (F) | |||
| 5 | H, I, J, W (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 6 | Y, Z (A, B) | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 405 (UniProt: Q11062)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 406 | - | expression tag |
| Arg 407 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91673.5 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 2646.6 | |
| All* | Total formula weight | 94320.1 |
