7TZC
 
 | | A drug and ATP binding site in type 1 ryanodine receptor | | Descriptor: | (2S)-3-(octadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Melville, Z, Dridi, H, Yuan, Q, Reiken, S, Anetta, W, Liu, Y, Clarke, O.B, Marks, A.R. | | Deposit date: | 2022-02-15 | | Release date: | 2022-05-18 | | Last modified: | 2022-07-20 | | Method: | ELECTRON MICROSCOPY (2.45 Å) | | Cite: | A drug and ATP binding site in type 1 ryanodine receptor.
Structure, 30, 2022
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8AHS
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3HR4
 | | Human iNOS Reductase and Calmodulin Complex | | Descriptor: | CALCIUM ION, Calmodulin, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Xia, C, Misra, I, Iyanaki, T, Kim, J.J.K. | | Deposit date: | 2009-06-08 | | Release date: | 2009-09-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Regulation of Interdomain Interactions by CaM in Inducible Nitric Oxide Synthase
J.Biol.Chem., 2009
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1YRU
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6DAH
 | | 2.5 Angstrom crystal structure of the N97S CaM mutant | | Descriptor: | CALCIUM ION, Calmodulin-1 | | Authors: | Wang, K, Van Petegem, F. | | Deposit date: | 2018-05-01 | | Release date: | 2018-10-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3OXQ
 | | Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex | | Descriptor: | CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C | | Authors: | Kim, E.Y, Rumpf, C.H, Van Petegem, F, Arant, R, Findeisen, F, Cooley, E.S, Isacoff, E.Y, Minor, D.L. | | Deposit date: | 2010-09-21 | | Release date: | 2010-11-03 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization.
Embo J., 29, 2010
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8FO6
 | | Nucleotide-free structure of a functional construct of eukaryotic elongation factor 2 kinase. | | Descriptor: | CALCIUM ION, Calmodulin-1, Eukaryotic elongation factor 2 kinase, ... | | Authors: | Piserchio, A, Isiorho, E.A, Dalby, K.N, Ghose, R. | | Deposit date: | 2022-12-29 | | Release date: | 2023-05-03 | | Method: | X-RAY DIFFRACTION (2.553 Å) | | Cite: | ADP enhances the allosteric activation of eukaryotic elongation factor 2 kinase by calmodulin.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8B6Q
 | | X-ray structure of the haloalkane dehalogenase HaloTag7 with an insertion of Calmodulin-M13 fusion at position 154-156 that mimic the structure of CaProLa, an calcium gated protein labeling technology | | Descriptor: | CALCIUM ION, CHLORIDE ION, Haloalkane dehalogenase,Calmodulin-1,Haloalkane dehalogenase,Calmodulin-1,M13 peptide | | Authors: | Tarnawski, M, Johnsson, K, Hiblot, J. | | Deposit date: | 2022-09-27 | | Release date: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | X-ray structure of the haloalkane dehalogenase HaloTag7 with an insertion of Calmodulin-M13 fusion at position 154-156 that mimic the structure of CaProLa, an calcium gated protein labeling technology
To Be Published
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3EWV
 | | Crystal Structure of calmodulin complexed with a peptide | | Descriptor: | CALCIUM ION, Calmodulin, Tumor necrosis factor receptor superfamily member 16 | | Authors: | Jiang, T, Cao, P, Gong, Y, Yu, H.J, Gui, W.J, Zhang, W.T. | | Deposit date: | 2008-10-16 | | Release date: | 2009-10-20 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural insights into the mechanism of calmodulin binding to death receptors.
Acta Crystallogr.,Sect.D, 70, 2014
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6B8Q
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3DVM
 | | Crystal Structure of Ca2+/CaM-CaV2.1 IQ domain complex | | Descriptor: | CALCIUM ION, Calmodulin, Voltage-dependent P/Q-type calcium channel subunit alpha-1A | | Authors: | Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L. | | Deposit date: | 2008-07-18 | | Release date: | 2008-11-04 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
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4GOW
 | | Crystal Structure of Ca2+/CaM:Kv7.4 (KCNQ4) B helix complex | | Descriptor: | CALCIUM ION, Calmodulin, Potassium voltage-gated channel subfamily KQT member 4 | | Authors: | Xu, Q, Chang, A, Tolia, A, Minor Jr, D.L. | | Deposit date: | 2012-08-20 | | Release date: | 2012-12-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of a Ca(2+)/CaM:Kv7.4 (KCNQ4) B-helix complex provides insight into M current modulation.
J.Mol.Biol., 425, 2013
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3O78
 | | The structure of Ca2+ Sensor (Case-12) | | Descriptor: | CALCIUM ION, Myosin light chain kinase, smooth muscle,Green fluorescent protein,Green fluorescent protein,Calmodulin-1 | | Authors: | Leder, L, Stark, W, Freuler, F, Marsh, M, Meyerhofer, M, Stettler, T, Mayr, L.M, Britanova, O.V, Strukova, L.A, Chudakov, D.M. | | Deposit date: | 2010-07-30 | | Release date: | 2010-09-29 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The structure of Ca2+ sensor Case16 reveals the mechanism of reaction to low Ca2+ concentrations
Sensors (Basel), 10, 2010
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3EVV
 | | Crystal Structure of Calcium bound dimeric GCAMP2 (#2) | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Wang, Q, Shui, B, Kotlikoff, M.I, Sondermann, H. | | Deposit date: | 2008-10-13 | | Release date: | 2008-12-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural Basis for Calcium Sensing by GCaMP2.
Structure, 16, 2008
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7ZRP
 | | 2.65 Angstrom crystal structure of Ca/CaM:CaMKIIdelta peptide complex | | Descriptor: | CALCIUM ION, Calcium/calmodulin-dependent protein kinase type II subunit delta, Calmodulin-1, ... | | Authors: | Helassa, N, Antonyuk, S. | | Deposit date: | 2022-05-04 | | Release date: | 2022-12-28 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Calmodulin variant E140G associated with long QT syndrome impairs CaMKII delta autophosphorylation and L-type calcium channel inactivation.
J.Biol.Chem., 299, 2022
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5COC
 | | Fusion protein of human calmodulin and B4 domain of protein A from staphylococcal aureus | | Descriptor: | CALCIUM ION, Immunoglobulin G-binding protein A,Calmodulin | | Authors: | Jeong, W.H, Lee, H, Song, D.H, Lee, J.O. | | Deposit date: | 2015-07-20 | | Release date: | 2016-03-30 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6691 Å) | | Cite: | Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker.
Nat Commun, 7, 2016
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7VUO
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7U9T
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6MUD
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8J05
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8J03
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8J04
 | | Human KCNQ2-CaM-HN37 complex in the presence of PIP2 | | Descriptor: | Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate | | Authors: | Ma, D, Li, X, Guo, J. | | Deposit date: | 2023-04-09 | | Release date: | 2023-12-06 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
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8XYA
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6K4K
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4BYF
 | | Crystal structure of human Myosin 1c in complex with calmodulin in the pre-power stroke state | | Descriptor: | ADP ORTHOVANADATE, CALMODULIN, MAGNESIUM ION, ... | | Authors: | Munnich, S, Taft, M.H, Pathan-Chhatbar, S, Manstein, D.J. | | Deposit date: | 2013-07-19 | | Release date: | 2014-03-26 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.74 Å) | | Cite: | Crystal Structure of Human Myosin 1C-the Motor in Glut4 Exocytosis: Implications for Ca(2+) Regulation and 14-3-3 Binding.
J.Mol.Biol., 426, 2014
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