3OXQ
Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex
Summary for 3OXQ
Entry DOI | 10.2210/pdb3oxq/pdb |
Descriptor | Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | ef hand iq domain, calcium sensing, calcium binding, ion channel, metal binding protein-transport protein complex, metal binding protein/transport protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton, spindle: P62158 Membrane; Multi-pass membrane protein: Q13936 |
Total number of polymer chains | 6 |
Total formula weight | 86234.65 |
Authors | Kim, E.Y.,Rumpf, C.H.,Van Petegem, F.,Arant, R.,Findeisen, F.,Cooley, E.S.,Isacoff, E.Y.,Minor, D.L. (deposition date: 2010-09-21, release date: 2010-11-03, Last modification date: 2023-09-06) |
Primary citation | Kim, E.Y.,Rumpf, C.H.,Van Petegem, F.,Arant, R.J.,Findeisen, F.,Cooley, E.S.,Isacoff, E.Y.,Minor, D.L. Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization. Embo J., 29:3924-3938, 2010 Cited by PubMed: 20953164DOI: 10.1038/emboj.2010.260 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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