1IWG
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1OY6
| Structural Basis of the Multiple Binding Capacity of the AcrB Multidrug Efflux Pump | Descriptor: | Acriflavine resistance protein B | Authors: | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.68 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1OY8
| Structural Basis of Multiple Drug Binding Capacity of the AcrB Multidrug Efflux Pump | Descriptor: | Acriflavine resistance protein B, RHODAMINE 6G | Authors: | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.63 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1OY9
| Structural Basis of Multiple Drug Binding Capacity of the AcrB Multidrug Efflux Pump | Descriptor: | Acriflavine resistance protein B, ETHIDIUM | Authors: | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1OYD
| Structural Basis of Multiple Binding Capacity of the AcrB multidrug Efflux Pump | Descriptor: | Acriflavine resistance protein B, DEQUALINIUM | Authors: | Yu, E.W, MeDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1OYE
| Structural Basis of Multiple Binding Capacity of the AcrB multidrug Efflux Pump | Descriptor: | 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, Acriflavine resistance protein B | Authors: | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.48 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1T9T
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1T9U
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1T9V
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1T9W
| Structural Basis of Multidrug Transport by the AcrB Multidrug Efflux Pump | Descriptor: | 6-[[(2-ETHOXY-1-NAPHTHALENYL)CARBONYL]AMINO]-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE, Acriflavine resistance protein B | Authors: | Yu, E.W, McDermott, G, Nikaido, H. | Deposit date: | 2004-05-18 | Release date: | 2005-10-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | A Periplasmic Drug-Binding Site of the AcrB Multidrug Efflux Pump: a Crystallographic and Site-Directed Mutagenesis Study J.Bacteriol., 187, 2005
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1T9X
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1T9Y
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2DHH
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2DR6
| Crystal structure of a multidrug transporter reveal a functionally rotating mechanism | Descriptor: | ACRB, DOXORUBICIN | Authors: | Murakami, S, Nakashima, R, Yamashita, E, Matsumoto, T. | Deposit date: | 2006-06-08 | Release date: | 2006-08-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structures of a multidrug transporter reveal a functionally rotating mechanism Nature, 443, 2006
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2DRD
| Crystal structure of a multidrug transporter reveal a functionally rotating mechanism | Descriptor: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, ACRB | Authors: | Murakami, S, Nakashima, R, Yamashita, E, Matsumoto, T. | Deposit date: | 2006-06-08 | Release date: | 2006-08-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structures of a multidrug transporter reveal a functionally rotating mechanism Nature, 443, 2006
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2GIF
| Asymmetric structure of trimeric AcrB from Escherichia coli | Descriptor: | Acriflavine resistance protein B, CITRATE ANION | Authors: | Seeger, M.A, Schiefner, A, Eicher, T, Verrey, F, Diederichs, K, Pos, K.M. | Deposit date: | 2006-03-28 | Release date: | 2006-09-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism. Science, 313, 2006
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2HQC
| Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway | Descriptor: | Acriflavine resistance protein B | Authors: | Su, C.-C, Li, M, Gu, R, Takatsuka, Y, McDermott, G, Nikaido, H, Yu, E.W. | Deposit date: | 2006-07-18 | Release date: | 2007-04-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.56 Å) | Cite: | Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway J.Bacteriol., 188, 2006
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2HQD
| Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway | Descriptor: | Acriflavine resistance protein B | Authors: | Su, C.-C, Li, M, Gu, R, Takatsuka, Y, McDermott, G, Nikaido, H, Yu, E.W. | Deposit date: | 2006-07-18 | Release date: | 2007-04-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway J.Bacteriol., 188, 2006
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2HQF
| Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway | Descriptor: | Acriflavine resistance protein B | Authors: | Su, C.-C, Li, M, Gu, R, Takatsuka, Y, McDermott, G, Nikaido, H, Yu, E.W. | Deposit date: | 2006-07-18 | Release date: | 2007-04-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.38 Å) | Cite: | Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway J.Bacteriol., 188, 2006
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2HQG
| Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway | Descriptor: | Acriflavine resistance protein B | Authors: | Su, C.-C, Li, M, Gu, R, Takatsuka, Y, McDermott, G, Nikaido, H, Yu, E.W. | Deposit date: | 2006-07-18 | Release date: | 2007-04-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.38 Å) | Cite: | Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway J.Bacteriol., 188, 2006
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2HRT
| Asymmetric structure of trimeric AcrB from Escherichia coli | Descriptor: | Acriflavine resistance protein B, CITRATE ANION | Authors: | Seeger, M.A, Schiefner, A, Eicher, T, Verrey, F, Diederichs, K, Pos, K.M. | Deposit date: | 2006-07-20 | Release date: | 2006-09-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism. Science, 313, 2006
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2I6W
| Crystal structure of the multidrug efflux transporter AcrB | Descriptor: | Acriflavine resistance protein B | Authors: | Das, D, Xu, Q.S, Kim, S.H. | Deposit date: | 2006-08-29 | Release date: | 2007-05-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of the multidrug efflux transporter AcrB at 3.1A resolution reveals the N-terminal region with conserved amino acids. J.Struct.Biol., 158, 2007
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2J8S
| Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors | Descriptor: | ACRIFLAVINE RESISTANCE PROTEIN B, DARPIN, DODECYL-ALPHA-D-MALTOSIDE, ... | Authors: | Sennhauser, G, Amstutz, P, Briand, C, Storchenegger, O, Gruetter, M.G. | Deposit date: | 2006-10-27 | Release date: | 2007-01-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Drug Export Pathway of Multidrug Exporter Acrb Revealed by Darpin Inhibitors. Plos Biol., 5, 2007
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2RDD
| X-ray crystal structure of AcrB in complex with a novel transmembrane helix. | Descriptor: | (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, Acriflavine resistance protein B, UPF0092 membrane protein yajC | Authors: | Tornroth-Horsefield, S, Gourdon, P, Horsefield, R, Neutze, R. | Deposit date: | 2007-09-22 | Release date: | 2007-12-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Crystal structure of AcrB in complex with a single transmembrane subunit reveals another twist. Structure, 15, 2007
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2V50
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