3ZID
 
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4U39
 | | Crystal Structure of FtsZ:MciZ Complex from Bacillus subtilis | | Descriptor: | Cell division factor, Cell division protein FtsZ, PHOSPHATE ION | | Authors: | Bisson-Filho, A.W, Discola, K.F, Castellen, P, Blasios, V, Martins, A, Sforca, M.L, Garcia, W, Zeri, A.C, Erickson, H.P, Dessen, A, Gueiros-Filho, F.J. | | Deposit date: | 2014-07-19 | | Release date: | 2015-03-18 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.194 Å) | | Cite: | Crystal Structure of FtsZ:MciZ Complex from Bacillus subtilis
To be Published
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4X1K
 | | Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications | | Descriptor: | 2-methyl-L-alanyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl}-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Parris, K.D. | | Deposit date: | 2014-11-24 | | Release date: | 2015-03-25 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications.
J.Med.Chem., 57, 2014
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1JFF
 | | Refined structure of alpha-beta tubulin from zinc-induced sheets stabilized with taxol | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Lowe, J, Li, H, Downing, K.H, Nogales, E. | | Deposit date: | 2001-06-20 | | Release date: | 2001-09-19 | | Last modified: | 2023-08-16 | | Method: | ELECTRON CRYSTALLOGRAPHY (3.5 Å) | | Cite: | Refined structure of alpha beta-tubulin at 3.5 A resolution.
J.Mol.Biol., 313, 2001
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5EIB
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4UXT
 | | Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN HEAVY CHAIN ISOFORM 5A, ... | | Authors: | Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C. | | Deposit date: | 2014-08-27 | | Release date: | 2014-09-24 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (7.4 Å) | | Cite: | Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
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7X0S
 | | Human TRiC-tubulin-S3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | Authors: | Cong, Y, Liu, C.X. | | Deposit date: | 2022-02-22 | | Release date: | 2023-04-12 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
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3CB2
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3N2K
 | | TUBULIN-NSC 613862: RB3 Stathmin-like domain complex | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M. | | Deposit date: | 2010-05-18 | | Release date: | 2010-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers.
J.Biol.Chem., 285, 2010
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2BTQ
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3N2G
 | | TUBULIN-NSC 613863: RB3 Stathmin-like domain complex | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M. | | Deposit date: | 2010-05-18 | | Release date: | 2010-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers.
J.Biol.Chem., 285, 2010
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2HXF
 | | KIF1A head-microtubule complex structure in amppnp-form | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | | Authors: | Kikkawa, M, Hirokawa, N. | | Deposit date: | 2006-08-03 | | Release date: | 2006-10-10 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (10 Å) | | Cite: | High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations
Embo J., 25, 2006
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2HXH
 | | KIF1A head-microtubule complex structure in adp-form | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Kikkawa, M, Hirokawa, N. | | Deposit date: | 2006-08-03 | | Release date: | 2006-10-10 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (11 Å) | | Cite: | High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations
Embo J., 25, 2006
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5LOV
 | | DZ-2384 tubulin complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, DZ 2384, ... | | Authors: | Prota, A.E, Steinmetz, M.O, Shore, G.C, Brouhard, G, Roulston, A. | | Deposit date: | 2016-08-10 | | Release date: | 2016-11-30 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.
Sci Transl Med, 8, 2016
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5LXS
 | | Tubulin-KS-1-199-32 complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Prota, A.E, Steinmetz, M.O. | | Deposit date: | 2016-09-22 | | Release date: | 2017-09-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Basis of Microtubule Stabilization by Discodermolide.
Chembiochem, 18, 2017
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5LP6
 | | Crystal structure of Tubulin-Stathmin-TTL-Thiocolchicine Complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Marangon, J, Christodoulou, M, Casagrande, F, Tiana, G, Dalla Via, L, Aliverti, A, Passarella, D, Cappelletti, G, Ricagno, S. | | Deposit date: | 2016-08-11 | | Release date: | 2016-09-21 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Tools for the rational design of bivalent microtubule-targeting drugs.
Biochem. Biophys. Res. Commun., 479, 2016
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1FSZ
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1Z2B
 | | Tubulin-colchicine-vinblastine: stathmin-like domain complex | | Descriptor: | (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Gigant, B, Wang, C, Ravelli, R.B.G, Roussi, F, Steinmetz, M.O, Curmi, P.A, Sobel, A, Knossow, M. | | Deposit date: | 2005-03-08 | | Release date: | 2005-05-31 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (4.1 Å) | | Cite: | Structural basis for the regulation of tubulin by vinblastine.
Nature, 435, 2005
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1Z5V
 | | Crystal structure of human gamma-tubulin bound to GTPgammaS | | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Tubulin gamma-1 chain | | Authors: | Aldaz, H.A, Rice, L.M, Stearns, T, Agard, D.A. | | Deposit date: | 2005-03-20 | | Release date: | 2005-05-31 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Insights into microtubule nucleation from the crystal structure of human gamma-tubulin.
Nature, 435, 2005
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1Z5W
 | | Crystal Structure of gamma-tubulin bound to GTP | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Tubulin gamma-1 chain | | Authors: | Aldaz, H.A, Rice, L.M, Stearns, T, Agard, D.A. | | Deposit date: | 2005-03-20 | | Release date: | 2005-05-31 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Insights into microtubule nucleation from the crystal structure of human gamma-tubulin.
Nature, 435, 2005
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1FFX
 | | TUBULIN:STATHMIN-LIKE DOMAIN COMPLEX | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, PROTEIN (STATHMIN-LIKE DOMAIN OF RB3), ... | | Authors: | Gigant, B, Martin-Barbey, C, Knossow, M. | | Deposit date: | 2000-07-26 | | Release date: | 2000-09-27 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3.95 Å) | | Cite: | The 4 A X-ray structure of a tubulin:stathmin-like domain complex.
Cell(Cambridge,Mass.), 102, 2000
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2Q1Y
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2P4N
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1IA0
 | | KIF1A HEAD-MICROTUBULE COMPLEX STRUCTURE IN ATP-FORM | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF1A, ... | | Authors: | Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N. | | Deposit date: | 2001-03-22 | | Release date: | 2002-03-22 | | Last modified: | 2021-10-27 | | Method: | ELECTRON MICROSCOPY (15 Å) | | Cite: | Switch-based Mechanism of Kinesin Motors
Nature, 411, 2001
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2Q1X
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