5JQG

An apo tubulin-RB-TTL complex structure used for side-by-side comparison

Summary for 5JQG

• Entry DOI: 10.2210/pdb5jqg/pdb
• Related: 5fnv
• Descriptor: Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total)
• Functional Keywords: apo structure, structural protein
• Biological source: Rattus norvegicus (Rat); More
• Cellular location: Cytoplasm, cytoskeleton: Q2XVP4 P02554; Golgi apparatus : P63043
• Total number of polymer chains: 6
• Total formula weight: 264608.42

Authors

Wang, Y.X.,Naismith, J.H.,Zhu, X. (deposition date: 2016-05-04, release date: 2016-05-18, Last modification date: 2023-11-08)

• Primary citation: Yang, J.,Wang, Y.X.,Wang, T.,Jiang, J.,Botting, C.H.,Liu, H.,Chen, Q.,Yang, J.,Naismith, J.H.,Zhu, X.,Chen, L.; Pironetin reacts covalently with cysteine-316 of alpha-tubulin to destabilize microtubule; Nat Commun, 7:12103-12103, 2016; PubMed: 27357539; DOI: 10.1038/ncomms12103

Experimental method

X-RAY DIFFRACTION (2.24 Å)