7OAH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oah by Molmil](/molmil-images/mine/7oah) | conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta2/A | Descriptor: | General control transcription factor GCN4,conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta2/A,General control transcription factor GCN4, TETRAETHYLENE GLYCOL | Authors: | Adlakha, J, Albrecht, R, Hartmann, M.D. | Deposit date: | 2021-04-19 | Release date: | 2022-05-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.694 Å) | Cite: | conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta2/A To Be Published
|
|
7OAD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oad by Molmil](/molmil-images/mine/7oad) | conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A, crystal form II | Descriptor: | General control transcription factor GCN4,conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A,General control transcription factor GCN4 | Authors: | Adlakha, J, Albrecht, R, Hartmann, M.D. | Deposit date: | 2021-04-19 | Release date: | 2022-05-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A, crystal form II To Be Published
|
|
7OAA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oaa by Molmil](/molmil-images/mine/7oaa) | |
7OOX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oox by Molmil](/molmil-images/mine/7oox) | Crystal structure of PIM1 in complex with ARC-3126 | Descriptor: | 1,2-ETHANEDIOL, Inhibitor ARC-3126, PHOSPHATE ION, ... | Authors: | Chaikuad, A, Dixon-Clarke, S.E, Nonga, O.E, Uri, A, Bullock, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-05-28 | Release date: | 2021-08-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family. Molecules, 26, 2021
|
|
7OOV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oov by Molmil](/molmil-images/mine/7oov) | Crystal structure of PIM1 in complex with ARC-1411 | Descriptor: | 1,2-ETHANEDIOL, Inhibitor ARC-1411, SULFATE ION, ... | Authors: | Chaikuad, A, Dixon-Clarke, S.E, Nonga, O.E, Uri, A, Bullock, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-05-28 | Release date: | 2021-08-04 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family. Molecules, 26, 2021
|
|
7OOW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oow by Molmil](/molmil-images/mine/7oow) | Crystal structure of PIM1 in complex with ARC-1415 | Descriptor: | 1,2-ETHANEDIOL, INHIBITOR ARC-1415, MAGNESIUM ION, ... | Authors: | Chaikuad, A, Dixon-Clarke, S.E, Nonga, O.E, Uri, A, Bullock, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-05-28 | Release date: | 2021-08-04 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family. Molecules, 26, 2021
|
|
2DLL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dll by Molmil](/molmil-images/mine/2dll) | Solution structure of the IRF domain of human interferon regulator factors 4 | Descriptor: | Interferon regulatory factor 4 | Authors: | Zhang, H.P, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-20 | Release date: | 2006-10-20 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the IRF domain of human interferon regulator factors 4 To be published
|
|
8JFV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jfv by Molmil](/molmil-images/mine/8jfv) | Crystal structure of Catabolite repressor acivator from E. coli in complex with sulisobenzone | Descriptor: | 1,2-ETHANEDIOL, 2-methoxy-4-oxidanyl-5-(phenylcarbonyl)benzenesulfonic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Neetu, N, Sharma, M, Mahto, J.K, Kumar, P. | Deposit date: | 2023-05-19 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Sulisobenzone is a potent inhibitor of the global transcription factor Cra. J.Struct.Biol., 215, 2023
|
|
5UFH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ufh by Molmil](/molmil-images/mine/5ufh) | The crystal structure of a LacI-type transcription regulator from Bifidobacterium animalis subsp. lactis DSM 10140 | Descriptor: | GLYCEROL, LacI-type transcriptional regulator, NITRATE ION | Authors: | Tan, K, Li, H, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2017-01-04 | Release date: | 2017-01-18 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The crystal structure of a LacI-type transcription regulator from Bifidobacterium animalis subsp. lactis DSM 10140 To Be Published
|
|
5O9Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5o9z by Molmil](/molmil-images/mine/5o9z) | |
8K3B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k3b by Molmil](/molmil-images/mine/8k3b) | |
7PO5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7po5 by Molmil](/molmil-images/mine/7po5) | |
7PNM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pnm by Molmil](/molmil-images/mine/7pnm) | |
7PNQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pnq by Molmil](/molmil-images/mine/7pnq) | |
7MY9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7my9 by Molmil](/molmil-images/mine/7my9) | Structure of proline utilization A with 1,3-dithiolane-2-carboxylate bound in the proline dehydrogenase active site | Descriptor: | 1,3-dithiolane-2-carboxylic acid, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ... | Authors: | Tanner, J.J, Campbell, A.C. | Deposit date: | 2021-05-20 | Release date: | 2021-09-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.628 Å) | Cite: | Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles. Acs Chem.Biol., 16, 2021
|
|
7MYB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7myb by Molmil](/molmil-images/mine/7myb) | |
7MYA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mya by Molmil](/molmil-images/mine/7mya) | |
7MYC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7myc by Molmil](/molmil-images/mine/7myc) | |
5XPG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xpg by Molmil](/molmil-images/mine/5xpg) | Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 6'U7' on the target strand | Descriptor: | 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*A P*GP*T)-3', 5'-R(*UP*AP*U*AP*CP*AP*AP*CP*CP*UP*AP*CP*AP*UP*AP*CP*CP*UP*CP* G)-3', MAGNESIUM ION, ... | Authors: | Sheng, G, Gogakos, T, Wang, J, Zhao, H, Serganov, A, Juranek, S, Tuschl, T, Patel, J.D, Wang, Y. | Deposit date: | 2017-06-02 | Release date: | 2018-04-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes. Nucleic Acids Res., 45, 2017
|
|
6B41
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b41 by Molmil](/molmil-images/mine/6b41) | Menin bound to M-525 | Descriptor: | Menin, methyl {(1S,2R)-2-[(S)-cyano[1-({1-[4-({1-[4-(dimethylamino)butanoyl]azetidin-3-yl}sulfonyl)phenyl]azetidin-3-yl}methyl)piperidin-4-yl](3-fluorophenyl)methyl]cyclopentyl}carbamate, praseodymium triacetate | Authors: | Stuckey, J.A. | Deposit date: | 2017-09-25 | Release date: | 2018-01-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Design of the First-in-Class, Highly Potent Irreversible Inhibitor Targeting the Menin-MLL Protein-Protein Interaction. Angew. Chem. Int. Ed. Engl., 57, 2018
|
|
3DKW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3dkw by Molmil](/molmil-images/mine/3dkw) | Crystal Structure of DNR from Pseudomonas aeruginosa. | Descriptor: | DNR protein | Authors: | Giardina, G. | Deposit date: | 2008-06-26 | Release date: | 2009-05-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | A dramatic conformational rearrangement is necessary for the activation of DNR from Pseudomonas aeruginosa. Crystal structure of wild-type DNR. Proteins, 2009
|
|
7N4W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n4w by Molmil](/molmil-images/mine/7n4w) | Complex structure of ROTU4 with rotundine | Descriptor: | GLYCEROL, ROTU4, SULFATE ION, ... | Authors: | Kim, W, Zhang, Y. | Deposit date: | 2021-06-04 | Release date: | 2022-06-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Using fungible biosensors to evolve improved alkaloid biosyntheses. Nat.Chem.Biol., 18, 2022
|
|
5UZ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uz4 by Molmil](/molmil-images/mine/5uz4) | The cryo-EM structure of YjeQ bound to the 30S subunit suggests a fidelity checkpoint function for this protein in ribosome assembly | Descriptor: | 16S RIBOSOMAL RNA, 3'-O-(N-methylanthraniloyl)-beta:gamma-imidoguanosine-5'-triphosphate, 30S ribosomal protein S10, ... | Authors: | Razi, A, Guarne, A, Ortega, J. | Deposit date: | 2017-02-24 | Release date: | 2017-04-19 | Last modified: | 2020-01-15 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | The cryo-EM structure of YjeQ bound to the 30S subunit suggests a fidelity checkpoint function for this protein in ribosome assembly. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
7NXZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nxz by Molmil](/molmil-images/mine/7nxz) | |
8ETS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ets by Molmil](/molmil-images/mine/8ets) | Class1 of the INO80-Hexasome complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... | Authors: | Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. | Deposit date: | 2022-10-17 | Release date: | 2023-07-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
|
|