7MYB

Structure of proline utilization A with tetrahydrothiophene-2-carboxylate bound in the proline dehydrogenase active site

Summary for 7MYB

Entry DOI	10.2210/pdb7myb/pdb
Descriptor	Bifunctional protein PutA, (2S)-thiolane-2-carboxylic acid, (2R)-thiolane-2-carboxylic acid, ... (10 entities in total)
Functional Keywords	flavoenzyme, rossmann fold, proline dehydrognease, aldehyde dehydrogenase, proline catabolism, substrate channeling, bifunctional enzyme, oxidoreductase
Biological source	Sinorhizobium meliloti (strain SM11)
Total number of polymer chains	2
Total formula weight	268189.31
Authors	Tanner, J.J.,Campbell, A.C. (deposition date: 2021-05-20, release date: 2021-09-29, Last modification date: 2023-10-18)
Primary citation	Campbell, A.C.,Prater, A.R.,Bogner, A.N.,Quinn, T.P.,Gates, K.S.,Becker, D.F.,Tanner, J.J. Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles. Acs Chem.Biol., 16:2268-2279, 2021 Cited by PubMed: 34542291 DOI: 10.1021/acschembio.1c00427 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.52 Å)

Structure validation