4AOM
 
 | | MTIP and MyoA complex | | Descriptor: | MYOSIN A TAIL DOMAIN INTERACTING PROTEIN, MYOSIN-A | | Authors: | Salgado, P.S, Douse, C.H, Simpson, P.J, Thomas, J.C, Holder, A.A, Tate, E.W, Cota, E. | | Deposit date: | 2012-03-29 | | Release date: | 2012-09-05 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.939 Å) | | Cite: | Regulation of the Plasmodium Motor Complex: Phosphorylation of Myosin a Tail Interacting Protein (Mtip) Loosens its Grip on Myoa
J.Biol.Chem., 287, 2012
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2PWC
 | | HIV-1 protease in complex with a amino decorated pyrrolidine-based inhibitor | | Descriptor: | CHLORIDE ION, GLYCEROL, Gag-Pol polyprotein (Pr160Gag-Pol), ... | | Authors: | Boettcher, J, Blum, A, Heine, A, Diederich, W.E, Klebe, G. | | Deposit date: | 2007-05-11 | | Release date: | 2008-04-15 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Structure-Guided Design of C2-Symmetric HIV-1 Protease Inhibitors Based on a Pyrrolidine Scaffold.
J.Med.Chem., 51, 2008
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4PAX
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2CLY
 | | Subcomplex of the stator of bovine mitochondrial ATP synthase | | Descriptor: | ATP SYNTHASE B CHAIN, MITOCHONDRIAL, ATP SYNTHASE COUPLING FACTOR 6, ... | | Authors: | Kane Dickson, V, Silvester, J.A, Fearnley, I.M, Leslie, A.G.W, Walker, J.E. | | Deposit date: | 2006-05-03 | | Release date: | 2006-06-28 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | On the Structure of the Stator of the Mitochondrial ATP Synthase.
Embo J., 25, 2006
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6JSN
 | | Crystal Structure of BACE1 in complex with N-{3-[(5R)-3-amino-5-methyl-9,9-dioxo-2,9lambda6-dithia-4-azaspiro[5.5]undec-3-en-5-yl]-4-fluorophenyl}-5-(fluoromethoxy)pyrazine-2-carboxamide | | Descriptor: | Beta-secretase 1, GLYCEROL, IODIDE ION, ... | | Authors: | Fujimoto, K, Matsuoka, E, Asada, N, Tadano, G, Yamamoto, T, Nakahara, K, Fuchino, K, Ito, H, Kanegawa, N, Moechars, D, Gijsen, H.J.M, Kusakabe, K.I. | | Deposit date: | 2019-04-08 | | Release date: | 2019-08-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure-Based Design of Selective beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: Targeting the Flap to Gain Selectivity over BACE2.
J.Med.Chem., 62, 2019
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1LDF
 | | CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) MUTATION W48F, F200T | | Descriptor: | GLYCEROL, Glycerol uptake facilitator protein, MAGNESIUM ION, ... | | Authors: | Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M. | | Deposit date: | 2002-04-08 | | Release date: | 2002-05-08 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Control of the selectivity of the aquaporin water channel family by global orientational tuning.
Science, 296, 2002
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2PXI
 | | Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate | | Descriptor: | 2'-DEOXY-5'-O-[(R)-{[(R)-[(R)-FLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]GUANOSINE, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ... | | Authors: | McKenna, C.E, Batra, V.K, Beard, W.A, Pedersen, L.C, Wilson, S.H. | | Deposit date: | 2007-05-14 | | Release date: | 2008-01-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | (R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta.
J.Am.Chem.Soc., 129, 2007
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5CZA
 | | Yeast 20S proteasome beta5-D166N mutant | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... | | Authors: | Huber, E.M, Groll, M. | | Deposit date: | 2015-07-31 | | Release date: | 2016-03-23 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
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4AMF
 | | Pseudomonas fluorescens PhoX in complex with the substrate analogue AppCp | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Yong, S.C, Roversi, P, Lillington, J.E.D, Zeldin, O.B, Garman, E.F, Lea, S.M, Berks, B.C. | | Deposit date: | 2012-03-09 | | Release date: | 2013-03-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | A Complex Iron-Calcium Cofactor Catalyzing Phosphotransfer Chemistry
Science, 345, 2014
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4J57
 | | Structure of Plasmodium falciparum thioredoxin reductase-thioredoxin complex | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Thioredoxin, ... | | Authors: | Fritz-Wolf, K, Jortzik, E, Stumpf, M, Preuss, J, Iozef, R, Rahlfs, S, Becker, K. | | Deposit date: | 2013-02-08 | | Release date: | 2013-07-10 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of the Plasmodium falciparum Thioredoxin Reductase-Thioredoxin Complex.
J.Mol.Biol., 425, 2013
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2V6H
 | | Crystal structure of the C1 domain of cardiac myosin binding protein-C | | Descriptor: | MYOSIN-BINDING PROTEIN C, CARDIAC-TYPE | | Authors: | Govata, L, Carpenter, L, Da Fonseca, P.C.A, Helliwell, J.R, Rizkallah, P.J, Flashman, E, Chayen, N.E, Redwood, C, Squire, J.M. | | Deposit date: | 2007-07-18 | | Release date: | 2008-07-22 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structure of the C1 domain of cardiac myosin binding protein-C: implications for hypertrophic cardiomyopathy.
J. Mol. Biol., 378, 2008
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2PZY
 | | Structure of MK2 Complexed with Compound 76 | | Descriptor: | (4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE, MAP kinase-activated protein kinase 2, STAUROSPORINE | | Authors: | White, A, Wu, J.P, Wang, J, Abeywardane, A, Andersen, D, Emmanuel, M, Gautschi, E, Goldberg, D.R, Kashem, M.A, Lukas, S, Mao, W, Martin, L, Morwick, T, Moss, N, Pargellis, C, Patel, U.R, Patnaude, L, Peet, G.W, Skow, D, Snow, R.J, Ward, Y, Werneburg, B. | | Deposit date: | 2007-05-18 | | Release date: | 2007-07-31 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The discovery of carboline analogs as potent MAPKAP-K2 inhibitors
Bioorg.Med.Chem.Lett., 17, 2007
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3M99
 | | Structure of the Ubp8-Sgf11-Sgf73-Sus1 SAGA DUB module | | Descriptor: | Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ... | | Authors: | Kohler, A, Zimmerman, E, Schneider, M, Hurt, E, Zheng, N. | | Deposit date: | 2010-03-21 | | Release date: | 2010-05-05 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module.
Cell(Cambridge,Mass.), 141, 2010
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2Q2V
 | | Structure of D-3-Hydroxybutyrate Dehydrogenase from Pseudomonas putida | | Descriptor: | Beta-D-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Paithankar, K.S, Feller, C, Kuettner, E.B, Keim, A, Grunow, M, Strater, N. | | Deposit date: | 2007-05-29 | | Release date: | 2007-10-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Cosubstrate-induced dynamics of D-3-hydroxybutyrate dehydrogenase from Pseudomonas putida.
Febs J., 274, 2007
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3RIF
 | | C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and glutamate. | | Descriptor: | (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, ... | | Authors: | Hibbs, R.E, Gouaux, E. | | Deposit date: | 2011-04-13 | | Release date: | 2011-05-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.345 Å) | | Cite: | Principles of activation and permeation in an anion-selective Cys-loop receptor.
Nature, 474, 2011
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3HBM
 | | Crystal Structure of PseG from Campylobacter jejuni | | Descriptor: | SULFATE ION, UDP-sugar hydrolase | | Authors: | Rangarajan, E.S, Proteau, A, Cygler, M, Matte, A, Sulea, T, Schoenhofen, I.C. | | Deposit date: | 2009-05-04 | | Release date: | 2009-05-26 | | Last modified: | 2021-10-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway.
J.Biol.Chem., 284, 2009
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4ER4
 | | HIGH-RESOLUTION X-RAY ANALYSES OF RENIN INHIBITOR-ASPARTIC PROTEINASE COMPLEXES | | Descriptor: | ENDOTHIAPEPSIN, H-142 | | Authors: | Foundling, S.I, Watson, F.E, Szelke, M, Blundell, T.L. | | Deposit date: | 1991-01-05 | | Release date: | 1991-04-15 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | High resolution X-ray analyses of renin inhibitor-aspartic proteinase complexes.
Nature, 327, 1987
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4K70
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1FRG
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3LZQ
 | | Crystal Structure Analysis of Manganese treated P19 protein from Campylobacter jejuni at 1.41 A at pH 9 | | Descriptor: | COPPER (II) ION, MANGANESE (II) ION, P19 protein, ... | | Authors: | Doukov, T.I, Chan, A.C.K, Scofield, M, Ramin, A.B, Tom-Yew, S.A.L, Murphy, M.E.P. | | Deposit date: | 2010-03-01 | | Release date: | 2010-07-21 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.41 Å) | | Cite: | Structure and Function of P19, a High-Affinity Iron Transporter of the Human Pathogen Campylobacter jejuni.
J.Mol.Biol., 401, 2010
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6JZH
 | | Structure of human A2A adenosine receptor in complex with ZM241385 obtained from SFX experiments under atmospheric pressure | | Descriptor: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, CHOLESTEROL, ... | | Authors: | Nango, E, Shimamura, T, Nakane, T, Yamanaka, Y, Mori, C, Kimura, K.T, Fujiwara, T, Tanaka, T, Iwata, S. | | Deposit date: | 2019-05-02 | | Release date: | 2019-10-30 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | High-viscosity sample-injection device for serial femtosecond crystallography at atmospheric pressure.
J.Appl.Crystallogr., 52, 2019
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1JMW
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2PID
 | | Crystal structure of human mitochondrial tyrosyl-tRNA synthetase in complex with an adenylate analog | | Descriptor: | 5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE, Tyrosyl-tRNA synthetase | | Authors: | Bonnefond, L, Frugier, M, Touze, E, Lorber, B, Florentz, C, Giege, R, Sauter, C, Rudinger-Thirion, J. | | Deposit date: | 2007-04-13 | | Release date: | 2007-10-23 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of Human Mitochondrial Tyrosyl-tRNA Synthetase Reveals Common and Idiosyncratic Features.
Structure, 15, 2007
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2VKC
 | | Solution structure of the B3BP Smr domain | | Descriptor: | NEDD4-BINDING PROTEIN 2 | | Authors: | Diercks, T, Ab, E, Daniels, M.A, deJong, R.N, Besseling, R, Kaptein, R, Folkers, G.E. | | Deposit date: | 2007-12-18 | | Release date: | 2008-10-14 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution Structure and Characterization of the DNA- Binding Activity of the B3BP-Smr Domain.
J.Mol.Biol., 383, 2008
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3GN8
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