2V6H
Crystal structure of the C1 domain of cardiac myosin binding protein-C
Summary for 2V6H
Entry DOI | 10.2210/pdb2v6h/pdb |
Related | 1GXE 1PD6 |
Descriptor | MYOSIN-BINDING PROTEIN C, CARDIAC-TYPE (2 entities in total) |
Functional Keywords | cell adhesion, phosphorylation, mybp-c c1 domain, disease mutation, muscle regulation, igi domain structure, muscle protein, cardiomyopathy, thick filament, immunoglobulin domain, hypertropic cardiomyopathy, polymorphism, actin-binding |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 12049.61 |
Authors | Govata, L.,Carpenter, L.,Da Fonseca, P.C.A.,Helliwell, J.R.,Rizkallah, P.J.,Flashman, E.,Chayen, N.E.,Redwood, C.,Squire, J.M. (deposition date: 2007-07-18, release date: 2008-07-22, Last modification date: 2024-05-08) |
Primary citation | Govada, L.,Carpenter, L.,da Fonseca, P.C.,Helliwell, J.R.,Rizkallah, P.,Flashman, E.,Chayen, N.E.,Redwood, C.,Squire, J.M. Crystal structure of the C1 domain of cardiac myosin binding protein-C: implications for hypertrophic cardiomyopathy. J. Mol. Biol., 378:387-397, 2008 Cited by PubMed: 18374358DOI: 10.1016/j.jmb.2008.02.044 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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