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1H02
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BU of 1h02 by Molmil
Human Insulin-like growth factor; SRS Daresbury data
Descriptor: INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE
Authors:Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z.
Deposit date:2002-06-11
Release date:2002-07-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
Biochemistry, 41, 2002
4CXN
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BU of 4cxn by Molmil
Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form I
Descriptor: INSULIN A CHAIN, INSULIN B CHAIN
Authors:Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L.
Deposit date:2014-04-07
Release date:2014-05-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin.
Biochemistry, 53, 2014
1HIQ
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BU of 1hiq by Molmil
PARADOXICAL STRUCTURE AND FUNCTION IN A MUTANT HUMAN INSULIN ASSOCIATED WITH DIABETES MELLITUS
Descriptor: INSULIN
Authors:Hua, Q.X, Shoelson, S.E, Inouye, K, Weiss, M.A.
Deposit date:1993-03-05
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Paradoxical structure and function in a mutant human insulin associated with diabetes mellitus.
Proc.Natl.Acad.Sci.USA, 90, 1993
1HUI
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BU of 1hui by Molmil
INSULIN MUTANT (B1, B10, B16, B27)GLU, DES-B30, NMR, 25 STRUCTURES
Descriptor: INSULIN
Authors:Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C.
Deposit date:1996-03-29
Release date:1997-03-12
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Solution structure of an engineered insulin monomer at neutral pH.
Biochemistry, 35, 1996
1HLS
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BU of 1hls by Molmil
NMR STRUCTURE OF THE HUMAN INSULIN-HIS(B16)
Descriptor: INSULIN
Authors:Ludvigsen, S, Kaarsholm, N.C.
Deposit date:1995-06-28
Release date:1995-09-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:High-resolution structure of an engineered biologically potent insulin monomer, B16 Tyr-->His, as determined by nuclear magnetic resonance spectroscopy.
Biochemistry, 33, 1994
1HO0
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BU of 1ho0 by Molmil
NEW B-CHAIN MUTANT OF BOVINE INSULIN
Descriptor: INSULIN
Authors:Dupradeau, F.Y, Richard, T, Le Flem, G, Oulyadi, H, Prigent, Y, Monti, J.P.
Deposit date:2000-12-08
Release date:2000-12-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A new B-chain mutant of insulin: comparison with the insulin crystal structure and role of sulfonate groups in the B-chain structure
J.Pept.Res., 60, 2002
4E7V
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BU of 4e7v by Molmil
The structure of R6 bovine insulin
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Harris, P, Frankaer, C.G, Knudsen, M.V.
Deposit date:2012-03-19
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
4EWX
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BU of 4ewx by Molmil
Human Insulin
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
Deposit date:2012-04-28
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
4EXX
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BU of 4exx by Molmil
Human Insulin
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
Deposit date:2012-05-01
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
4EY1
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BU of 4ey1 by Molmil
Human Insulin
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
Deposit date:2012-05-01
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.471 Å)
Cite:Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
4E7T
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BU of 4e7t by Molmil
The structure of T6 bovine insulin
Descriptor: Insulin A chain, Insulin B chain, ZINC ION
Authors:Harris, P, Frankaer, C.G, Knudsen, M.V.
Deposit date:2012-03-19
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
4EX1
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BU of 4ex1 by Molmil
Human Insulin
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
Deposit date:2012-04-29
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.657 Å)
Cite:Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
4EY9
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BU of 4ey9 by Molmil
Human Insulin
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
Deposit date:2012-05-01
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.471 Å)
Cite:Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
4EYD
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BU of 4eyd by Molmil
Human Insulin
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
Deposit date:2012-05-01
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.471 Å)
Cite:Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
4EWZ
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BU of 4ewz by Molmil
Human Insulin
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
Deposit date:2012-04-29
Release date:2013-05-01
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.791 Å)
Cite:Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
4E7U
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BU of 4e7u by Molmil
The structure of T3R3 bovine insulin
Descriptor: Insulin A chain, Insulin B chain, THIOCYANATE ION, ...
Authors:Harris, P, Frankaer, C.G, Knudsen, M.V.
Deposit date:2012-03-19
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
5BOQ
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BU of 5boq by Molmil
Human insulin with intra-chain chemical crosslink between modified B24 and B29
Descriptor: Insulin, SULFATE ION
Authors:Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L.
Deposit date:2015-05-27
Release date:2016-02-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Sci Rep, 6, 2016
5T7R
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BU of 5t7r by Molmil
A6-A11 trans-dicarba human insulin
Descriptor: Insulin A chain, Insulin B chain
Authors:Menting, J.G, Lawrence, M.C, Robinson, A.J, Forbes, B.E.
Deposit date:2016-09-05
Release date:2017-12-06
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity.
Sci Rep, 7, 2017
5BPO
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BU of 5bpo by Molmil
Human insulin with intra-chain chemical crosslink between modified B27 and B29
Descriptor: Insulin
Authors:Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L.
Deposit date:2015-05-28
Release date:2016-02-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Sci Rep, 6, 2016
5CO6
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BU of 5co6 by Molmil
Crystal structure of human zinc insulin at pH 6.5
Descriptor: CHLORIDE ION, Insulin, MAGNESIUM ION, ...
Authors:Lima, L.M.T.R, PALMIERI, L.C.
Deposit date:2015-07-19
Release date:2015-08-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human zinc insulin at pH 6.5
To Be Published
5CO9
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BU of 5co9 by Molmil
Crystal structure of human zinc insulin at pH 6.5
Descriptor: CHLORIDE ION, Insulin, ZINC ION
Authors:Lima, L.M.T.R, Palmieri, L.C.
Deposit date:2015-07-20
Release date:2015-08-26
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of human zinc insulin at pH 6.5
To Be Published
5USP
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BU of 5usp by Molmil
Insulin with proline analog Pip at position B28 in the T2 state
Descriptor: Insulin Chain A, Insulin Chain B, SODIUM ION
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-13
Release date:2018-02-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.174 Å)
Cite:Insulin with proline analog Pip at position B28 in the T2 state
To Be Published
5USS
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BU of 5uss by Molmil
Insulin with proline analog PiP at position B28 in the R6 state
Descriptor: CHLORIDE ION, Insulin Chain A, Insulin Chain B, ...
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-13
Release date:2018-02-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.061 Å)
Cite:Insulin with proline analog PiP at position B28 in the R6 state
To Be Published
5UU4
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BU of 5uu4 by Molmil
Insulin with proline analog ThioP at position B28 in the R6 state
Descriptor: CHLORIDE ION, Insulin A Chain, Insulin B Chain, ...
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-16
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.973 Å)
Cite:Insulin with proline analog ThioP at position B28 in the R6 state
To Be Published
5UU2
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BU of 5uu2 by Molmil
Insulin with proline analog ThioP at position B28 in the T2 state
Descriptor: Insulin Chain A, Insulin Chain B
Authors:Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
Deposit date:2017-02-15
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.223 Å)
Cite:Insulin with proline analog ThioP at position B28 in the T2 state
To Be Published

221051

数据于2024-06-12公开中

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