5WBT
Solution Structure and Dynamics of an Ultra-Stable Single-Chain Insulin Analog STUDIES OF AN ENGINEERED MONOMER AND IMPLICATIONS FOR RECEPTOR BINDING
Summary for 5WBT
Entry DOI | 10.2210/pdb5wbt/pdb |
NMR Information | BMRB: 30314 |
Descriptor | Insulin (1 entity in total) |
Functional Keywords | heat-stable, hormone |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 6515.31 |
Authors | Glidden, M.D.,Yang, Y.,Wickramasinghe, N.P.,Weiss, M.A. (deposition date: 2017-06-29, release date: 2017-11-15, Last modification date: 2023-06-14) |
Primary citation | Glidden, M.D.,Yang, Y.,Smith, N.A.,Phillips, N.B.,Carr, K.,Wickramasinghe, N.P.,Ismail-Beigi, F.,Lawrence, M.C.,Smith, B.J.,Weiss, M.A. Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding. J. Biol. Chem., 293:69-88, 2018 Cited by PubMed: 29114034DOI: 10.1074/jbc.M117.808667 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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