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2AT2
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BU of 2at2 by Molmil
MOLECULAR STRUCTURE OF BACILLUS SUBTILIS ASPARTATE TRANSCARBAMOYLASE AT 3.0 ANGSTROMS RESOLUTION
Descriptor: ASPARTATE CARBAMOYLTRANSFERASE
Authors:Stevens, R.C, Reinisch, K.M, Lipscomb, W.N.
Deposit date:1992-07-20
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular structure of Bacillus subtilis aspartate transcarbamoylase at 3.0 A resolution.
Proc.Natl.Acad.Sci.USA, 88, 1991
1RHM
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BU of 1rhm by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A NICOTINIC ACID ALDEHYDE INHIBITOR
Descriptor: 4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID, CASP-3
Authors:Becker, J.W, Rotonda, J, Soisson, S.M.
Deposit date:2003-11-14
Release date:2004-05-11
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis.
J.Med.Chem., 47, 2004
2BC2
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BU of 2bc2 by Molmil
METALLO BETA-LACTAMASE II FROM BACILLUS CEREUS 569/H/9 AT PH 6.0, TRIGONAL CRYSTAL FORM
Descriptor: METALLO BETA-LACTAMASE II, SULFATE ION, ZINC ION
Authors:Fabiane, S.M, Sutton, B.J.
Deposit date:1997-09-09
Release date:1999-04-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Null
To be Published
2AZO
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BU of 2azo by Molmil
DNA MISMATCH REPAIR PROTEIN MUTH FROM E. COLI
Descriptor: MUTH
Authors:Yang, W.
Deposit date:1997-11-20
Release date:1998-05-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases.
EMBO J., 17, 1998
2ALP
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BU of 2alp by Molmil
REFINED STRUCTURE OF ALPHA-LYTIC PROTEASE AT 1.7 ANGSTROMS RESOLUTION. ANALYSIS OF HYDROGEN BONDING AND SOLVENT STRUCTURE
Descriptor: ALPHA-LYTIC PROTEASE, SULFATE ION
Authors:Fujinaga, M, Delbaere, L.T.J, Brayer, G.D, James, M.N.G.
Deposit date:1985-03-07
Release date:1985-07-17
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Refined structure of alpha-lytic protease at 1.7 A resolution. Analysis of hydrogen bonding and solvent structure.
J.Mol.Biol., 184, 1985
2AT9
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STRUCTURE OF BACTERIORHODOPSIN AT 3.0 ANGSTROM BY ELECTRON CRYSTALLOGRAPHY
Descriptor: 3-[[3-METHYLPHOSPHONO-GLYCEROLYL]PHOSPHONYL]-[1,2-DI[2,6,10,14-TETRAMETHYL-HEXADECAN-16-YL]GLYCEROL, BACTERIORHODOPSIN, RETINAL
Authors:Mitsuoka, K, Hirai, T, Murata, K, Miyazawa, A, Kidera, A, Kimura, Y, Fujiyoshi, Y.
Deposit date:1998-12-17
Release date:1999-04-27
Last modified:2024-10-23
Method:ELECTRON CRYSTALLOGRAPHY (3 Å)
Cite:The structure of bacteriorhodopsin at 3.0 A resolution based on electron crystallography: implication of the charge distribution.
J.Mol.Biol., 286, 1999
1RMH
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BU of 1rmh by Molmil
RECOMBINANT CYCLOPHILIN A FROM HUMAN T CELL
Descriptor: AAPF PEPTIDE SUBSTRATE, CYCLOPHILIN A
Authors:Zhao, Y, Ke, H.
Deposit date:1995-07-31
Release date:1996-10-14
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure implies that cyclophilin predominantly catalyzes the trans to cis isomerization.
Biochemistry, 35, 1996
2BBQ
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BU of 2bbq by Molmil
STRUCTURAL BASIS FOR RECOGNITION OF POLYGLUTAMYL FOLATES BY THYMIDYLATE SYNTHASE
Descriptor: 10-PARPARGYL-5,8-DIDEAZAFOLATE-4-GLUTAMIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
Authors:Kamb, A, Finer-Moore, J, Stroud, R.M.
Deposit date:1992-09-16
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for recognition of polyglutamyl folates by thymidylate synthase.
Biochemistry, 31, 1992
1RN7
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BU of 1rn7 by Molmil
Structure of human cystatin D
Descriptor: Cystatin D
Authors:Alvarez-Fernandez, M, Liang, Y.H, Abrahamson, M, Su, X.D.
Deposit date:2003-11-30
Release date:2004-05-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human cystatin D, a cysteine peptidase inhibitor with restricted inhibition profile.
J.Biol.Chem., 280, 2005
1RNR
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BU of 1rnr by Molmil
AUTOCATALYTIC GENERATION OF DOPA IN THE ENGINEERED PROTEIN R2 F208Y FROM ESCHERICHIA COLI RIBONUCLEOTIDE REDUCTASE AND CRYSTAL STRUCTURE OF THE DOPA-208 PROTEIN
Descriptor: FE (III) ION, MERCURY (II) ION, RIBONUCLEOTIDE REDUCTASE R1 PROTEIN
Authors:Aberg, A, Nordlund, P.
Deposit date:1993-04-26
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Autocatalytic generation of dopa in the engineered protein R2 F208Y from Escherichia coli ribonucleotide reductase and crystal structure of the dopa-208 protein.
Biochemistry, 32, 1993
2BEB
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BU of 2beb by Molmil
X-ray structure of Asn to Thr mutant of Winged Bean Chymotrypsin inhibitor
Descriptor: Chymotrypsin inhibitor 3
Authors:Dattagupta, J.K, Sen, U, Dasgupta, J, Khamrui, S.
Deposit date:2005-10-24
Release date:2006-06-13
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Spacer Asn Determines the Fate of Kunitz (STI) Inhibitors, as Revealed by Structural and Biochemical Studies on WCI Mutants.
Biochemistry, 45, 2006
2BE5
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BU of 2be5 by Molmil
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with inhibitor tagetitoxin
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Vassylyev, D.G, Svetlov, V, Vassylyeva, M.N, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Artsimovitch, I, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-10-22
Release date:2005-11-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for transcription inhibition by tagetitoxin
Nat.Struct.Mol.Biol., 12, 2005
1RVJ
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BU of 1rvj by Molmil
PHOTOSYNTHETIC REACTION CENTER DOUBLE MUTANT FROM RHODOBACTER SPHAEROIDES WITH ASP L213 REPLACED WITH ASN AND ARG H177 REPLACED WITH HIS
Descriptor: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ...
Authors:Xu, Q, Axelrod, H.L, Abresch, E.C, Paddock, M.L, Okamura, M.Y, Feher, G.
Deposit date:2003-12-14
Release date:2004-04-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:X-Ray Structure Determination of Three Mutants of the Bacterial Photosynthetic Reaction Centers from Rb. sphaeroides; Altered Proton Transfer Pathways.
Structure, 12, 2004
1Z94
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BU of 1z94 by Molmil
X-Ray Crystal Structure of Protein CV1439 from Chromobacterium violaceum. Northeast Structural Genomics Consortium Target CvR12.
Descriptor: conserved hypothetical protein
Authors:Kuzin, A, Vorobiev, S.M, Yong, W, Forouhar, F, Xio, R, Ma, L.-C, Acton, T, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-03-31
Release date:2005-05-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the Hypothetical Protein CV1439 from Chromobacterium violaceum. Northeast Structural Genomics Consortium Target CVR12.
To be Published
1RWE
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BU of 1rwe by Molmil
Enhancing the activity of insulin at receptor edge: crystal structure and photo-cross-linking of A8 analogues
Descriptor: CHLORIDE ION, Insulin, PHENOL, ...
Authors:Wan, Z, Xu, B, Chu, Y.C, Li, B, Nakagawa, S.H, Qu, Y, Hu, S.Q, Katsoyannis, P.G, Weiss, M.A.
Deposit date:2003-12-16
Release date:2005-02-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues.
Biochemistry, 43, 2004
1R2F
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BU of 1r2f by Molmil
RIBONUCLEOTIDE REDUCTASE R2F PROTEIN FROM SALMONELLA TYPHIMURIUM
Descriptor: FE (III) ION, PROTEIN (RIBONUCLEOTIDE REDUCTASE R2)
Authors:Eklund, H, Eriksson, M.
Deposit date:1998-08-24
Release date:1999-01-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Salmonella typhimurium nrdF ribonucleotide reductase in its oxidized and reduced forms.
Biochemistry, 37, 1998
1R2Y
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BU of 1r2y by Molmil
MutM (Fpg) bound to 8-oxoguanine (oxoG) containing DNA
Descriptor: 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ...
Authors:Fromme, J.C, Verdine, G.L.
Deposit date:2003-09-30
Release date:2003-10-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:DNA Lesion Recognition by the Bacterial Repair Enzyme MutM.
J.Biol.Chem., 278, 2003
1R35
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BU of 1r35 by Molmil
MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER, TETRAHYDROBIOPTERIN AND 4R-FLUORO-N6-ETHANIMIDOYL-L-LYSINE
Descriptor: 4R-FLUORO-N6-ETHANIMIDOYL-L-LYSINE, 5,6,7,8-TETRAHYDROBIOPTERIN, Nitric oxide synthase, ...
Authors:Shieh, H.S, Stevens, A.M, Stallings, W.C.
Deposit date:2003-09-30
Release date:2004-10-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:4-Fluorinated L-lysine analogs as selective i-NOS inhibitors: methodology for introducing fluorine into the lysine side chain.
Org.Biomol.Chem., 1, 2003
1ZC6
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BU of 1zc6 by Molmil
Crystal Structure of Putative N-acetylglucosamine Kinase from Chromobacterium violaceum. Northeast Structural Genomics Target Cvr23.
Descriptor: probable N-acetylglucosamine kinase
Authors:Vorobiev, S.M, Kuzin, A, Forouhar, F, Abashidze, M, Acton, T.B, Xiao, R, Ma, L.-C, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-04-11
Release date:2005-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Putative N-acetylglucosamine Kinase from Chromobacterium violaceum
To be Published
1RNV
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BU of 1rnv by Molmil
REFINEMENT OF THE CRYSTAL STRUCTURE OF RIBONUCLEASE S. COMPARISON WITH AND BETWEEN THE VARIOUS RIBONUCLEASE A STRUCTURES
Descriptor: RIBONUCLEASE S, SULFATE ION
Authors:Kim, E.E, Varadarajan, R, Wyckoff, H.W, Richards, F.M.
Deposit date:1992-02-19
Release date:1994-01-31
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Refinement of the crystal structure of ribonuclease S. Comparison with and between the various ribonuclease A structures.
Biochemistry, 31, 1992
2BIR
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BU of 2bir by Molmil
ADDITIVITY OF SUBSTRATE BINDING IN RIBONUCLEASE T1 (Y42A MUTANT)
Descriptor: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1
Authors:Doumen, J, Steyaert, J, Loverix, S.
Deposit date:1996-12-03
Release date:1997-06-16
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Additivity of protein-guanine interactions in ribonuclease T1.
J.Biol.Chem., 272, 1997
1Z6E
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BU of 1z6e by Molmil
Factor XA in complex with the inhibitor 1-(3'-amino-1,2-benzisoxazol-5'-yl)-n-(4-(2'-((dimethylamino)methyl)-1h-imidazol-1-yl)-2-fluorophenyl)-3-(trifluoromethyl)-1h-pyrazole-5-carboxamide (razaxaban; DPC906; BMS-561389)
Descriptor: 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-N-(4-{2-[(DIMETHYLAMINO)METHYL]-1H-IMIDAZOL-1-YL}-2-FLUOROPHENYL)-3-(TRIFLUOROMETHYL) -1H-PYRAZOLE-5-CARBOXAMIDE, Coagulation factor X
Authors:Alexander, R.S.
Deposit date:2005-03-22
Release date:2006-03-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4-[(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor.
J.Med.Chem., 48, 2005
2BFY
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BU of 2bfy by Molmil
Complex of Aurora-B with INCENP and Hesperadin.
Descriptor: AURORA KINASE B-A, INNER CENTROMERE PROTEIN A, N-[2-OXO-3-((E)-PHENYL{[4-(PIPERIDIN-1-YLMETHYL)PHENYL]IMINO}METHYL)-2,6-DIHYDRO-1H-INDOL-5-YL]ETHANESULFONAMIDE
Authors:Sessa, F, Mapelli, M, Ciferri, C, Tarricone, C, Areces, L.B, Schneider, T.R, Stukenberg, P.T, Musacchio, A.
Deposit date:2004-12-15
Release date:2005-05-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanism of Aurora B Activation by Incenp and Inhibition by Hesperadin
Mol.Cell, 18, 2005
2BN4
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BU of 2bn4 by Molmil
A second FMN-binding site in yeast NADPH-cytochrome P450 reductase suggests a novel mechanism of electron transfer by diflavin reductase
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Podust, L.M, Lepesheva, G.I, Kim, Y, Yermalitskaya, L.V, Yermalitsky, V.N, Lamb, D.C, Kelly, S.L, Waterman, M.R.
Deposit date:2005-03-18
Release date:2006-01-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:A Second Fmn-Binding Site in Yeast Nadph-Cytochrome P450 Reductase Suggests a Mechanism of Electron Transfer by Diflavin Reductases.
Structure, 14, 2006
2BE2
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Crystal structure of HIV-1 reverse transcriptase (RT) in complex with R221239
Descriptor: 4-(3,5-DIMETHYLPHENOXY)-5-(FURAN-2-YLMETHYLSULFANYLMETHYL)-3-IODO-6-METHYLPYRIDIN-2(1H)-ONE, GLYCEROL, MANGANESE (II) ION, ...
Authors:Himmel, D.M, Das, K, Clark Jr, A.D, Hughes, S.H, Benjahad, A, Oumouch, S, Guillemont, J, Coupa, S, Poncelet, A, Csoka, I, Meyer, C, Andries, K, Nguyen, C.H, Grierson, D.S, Arnold, E.
Deposit date:2005-10-21
Release date:2005-12-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains.
J.Med.Chem., 48, 2005

226707

数据于2024-10-30公开中

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