2BBQ

STRUCTURAL BASIS FOR RECOGNITION OF POLYGLUTAMYL FOLATES BY THYMIDYLATE SYNTHASE

Summary for 2BBQ

Entry DOI	10.2210/pdb2bbq/pdb
Descriptor	THYMIDYLATE SYNTHASE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 10-PARPARGYL-5,8-DIDEAZAFOLATE-4-GLUTAMIC ACID, ... (4 entities in total)
Functional Keywords	transferase(methyltransferase)
Biological source	Escherichia coli
Cellular location	Cytoplasm: P0A884
Total number of polymer chains	2
Total formula weight	63377.29
Authors	Kamb, A.,Finer-Moore, J.,Stroud, R.M. (deposition date: 1992-09-16, release date: 1994-01-31, Last modification date: 2024-06-05)
Primary citation	Kamb, A.,Finer-Moore, J.,Calvert, A.H.,Stroud, R.M. Structural basis for recognition of polyglutamyl folates by thymidylate synthase. Biochemistry, 31:9883-9890, 1992 Cited by PubMed: 1390771 DOI: 10.1021/bi00156a005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation