1R35
MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER, TETRAHYDROBIOPTERIN AND 4R-FLUORO-N6-ETHANIMIDOYL-L-LYSINE
Summary for 1R35
Entry DOI | 10.2210/pdb1r35/pdb |
Descriptor | Nitric oxide synthase, inducible, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total) |
Functional Keywords | nitric oxide monooxygenase, heme, dimer, intermediate, pterin, h4b, tetrahydrobiopterin, oxidoreductase |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 2 |
Total formula weight | 102463.90 |
Authors | Shieh, H.S.,Stevens, A.M.,Stallings, W.C. (deposition date: 2003-09-30, release date: 2004-10-05, Last modification date: 2023-08-23) |
Primary citation | Hallinan, E.A.,Kramer, S.W.,Houdek, S.C.,Moore, W.M.,Jerome, G.M.,Spangler, D.P.,Stevens, A.M.,Shieh, H.S.,Manning, P.T.,Pitzele, B.S. 4-Fluorinated L-lysine analogs as selective i-NOS inhibitors: methodology for introducing fluorine into the lysine side chain. Org.Biomol.Chem., 1:3527-3534, 2003 Cited by PubMed: 14599013DOI: 10.1039/b307563j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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