1R35

MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER, TETRAHYDROBIOPTERIN AND 4R-FLUORO-N6-ETHANIMIDOYL-L-LYSINE

Summary for 1R35

DescriptorNitric oxide synthase, inducible, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total)
Functional Keywordsnitric oxide monooxygenase, heme, dimer, intermediate, pterin, h4b, tetrahydrobiopterin, oxidoreductase
Biological sourceMus musculus (house mouse)
Total number of polymer chains2
Total molecular weight102463.9
Authors
Shieh, H.S.,Stevens, A.M.,Stallings, W.C. (deposition date: 2003-09-30, release date: 2004-10-05, Last modification date: 2017-10-11)
Primary citation
Hallinan, E.A.,Kramer, S.W.,Houdek, S.C.,Moore, W.M.,Jerome, G.M.,Spangler, D.P.,Stevens, A.M.,Shieh, H.S.,Manning, P.T.,Pitzele, B.S.
4-Fluorinated L-lysine analogs as selective i-NOS inhibitors: methodology for introducing fluorine into the lysine side chain.
Org.Biomol.Chem., 1:3527-3534, 2003
PubMed: 14599013 (PDB entries with the same primary citation)
DOI: 10.1039/b307563j
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers150.5%6.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution