1HSW
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1DG8
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![BU of 1dg8 by Molmil](/molmil-images/mine/1dg8) | DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH | Descriptor: | DIHYDROFOLATE REDUCTASE, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Li, R, Sirawaraporn, R, Chitnumsub, P, Sirawaraporn, W, Wooden, J, Athappilly, F, Turley, S, Hol, W.G. | Deposit date: | 1999-11-23 | Release date: | 2000-03-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs. J.Mol.Biol., 295, 2000
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1DG5
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![BU of 1dg5 by Molmil](/molmil-images/mine/1dg5) | DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND TRIMETHOPRIM | Descriptor: | DIHYDROFOLATE REDUCTASE, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Li, R, Sirawaraporn, R, Chitnumsub, P, Sirawaraporn, W, Wooden, J, Athappilly, F, Turley, S, Hol, W.G. | Deposit date: | 1999-11-23 | Release date: | 2000-03-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs. J.Mol.Biol., 295, 2000
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1DCD
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![BU of 1dcd by Molmil](/molmil-images/mine/1dcd) | DESULFOREDOXIN COMPLEXED WITH CD2+ | Descriptor: | CADMIUM ION, PROTEIN (DESULFOREDOXIN) | Authors: | Archer, M, Carvalho, A.L, Teixeira, S, Romao, M.J. | Deposit date: | 1999-03-20 | Release date: | 1999-07-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural studies by X-ray diffraction on metal substituted desulforedoxin, a rubredoxin-type protein. Protein Sci., 8, 1999
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1DF7
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![BU of 1df7 by Molmil](/molmil-images/mine/1df7) | DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND METHOTREXATE | Descriptor: | DIHYDROFOLATE REDUCTASE, GLYCEROL, METHOTREXATE, ... | Authors: | Li, R, Sirawaraporn, R, Chitnumsub, P, Sirawaraporn, W, Wooden, J, Athappilly, F, Turley, S, Hol, W.G. | Deposit date: | 1999-11-17 | Release date: | 2000-03-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs. J.Mol.Biol., 295, 2000
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1IZ4
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2BOG
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![BU of 2bog by Molmil](/molmil-images/mine/2bog) | Catalytic domain of endo-1,4-glucanase Cel6A mutant Y73S from Thermobifida fusca in complex with methyl cellobiosyl-4-thio-beta- cellobioside | Descriptor: | ENDOGLUCANASE E-2, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-methyl beta-D-glucopyranoside | Authors: | Larsson, A.M, Bergfors, T, Dultz, E, Irwin, D.C, Roos, A, Driguez, H, Wilson, D.B, Jones, T.A. | Deposit date: | 2005-04-10 | Release date: | 2005-10-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.04 Å) | Cite: | Crystal Structure of Thermobifida Fusca Endoglucanase Cel6A in Complex with Substrate and Inhibitor: The Role of Tyrosine Y73 in Substrate Ring Distortion. Biochemistry, 44, 2005
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2BOD
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![BU of 2bod by Molmil](/molmil-images/mine/2bod) | Catalytic domain of endo-1,4-glucanase Cel6A from Thermobifida fusca in complex with methyl cellobiosyl-4-thio-beta-cellobioside | Descriptor: | ENDOGLUCANASE E-2, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-methyl beta-D-glucopyranoside | Authors: | Larsson, A.M, Bergfors, T, Dultz, E, Irwin, D.C, Roos, A, Driguez, H, Wilson, D.B, Jones, T.A. | Deposit date: | 2005-04-10 | Release date: | 2005-10-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure of Thermobifida Fusca Endoglucanase Cel6A in Complex with Substrate and Inhibitor: The Role of Tyrosine Y73 in Substrate Ring Distortion. Biochemistry, 44, 2005
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1IQH
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![BU of 1iqh by Molmil](/molmil-images/mine/1iqh) | Human coagulation factor Xa in complex with M55143 | Descriptor: | 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[4-HYDROXYMETHYL-1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE, CALCIUM ION, coagulation Factor Xa | Authors: | Shiromizu, I, Matsusue, T. | Deposit date: | 2001-07-23 | Release date: | 2003-09-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Factor Xa Specific Inhibitor that Induces the Novel Binding Model in Complex with Human Fxa To be Published
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2CBY
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![BU of 2cby by Molmil](/molmil-images/mine/2cby) | Crystal structure of the ATP-dependent Clp Protease proteolytic subunit 1 (ClpP1) from Mycobacterium tuberculosis | Descriptor: | ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 | Authors: | Mate, M.J, Portnoi, D, Alzari, P.M, Ortiz-Lombardia, M. | Deposit date: | 2006-01-10 | Release date: | 2006-01-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1. Acta Crystallogr.,Sect.D, 63, 2007
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1EOE
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![BU of 1eoe by Molmil](/molmil-images/mine/1eoe) | CRYSTAL STRUCTURE OF THE V135R MUTANT OF A SHAKER T1 DOMAIN | Descriptor: | POTASSIUM CHANNEL KV1.1 | Authors: | Nanao, M.H, Cushman, S.J, Jahng, A.W, DeRubeis, D, Choe, S, Pfaffinger, P.J. | Deposit date: | 2000-03-22 | Release date: | 2000-05-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.704 Å) | Cite: | Voltage dependent activation of potassium channels is coupled to T1 domain structure. Nat.Struct.Biol., 7, 2000
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2RG3
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![BU of 2rg3 by Molmil](/molmil-images/mine/2rg3) | Covalent complex structure of elastase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Leukocyte elastase | Authors: | Huang, W, Yamamoto, Y. | Deposit date: | 2007-10-02 | Release date: | 2008-07-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray snapshot of the mechanism of inactivation of human neutrophil elastase by 1,2,5-thiadiazolidin-3-one 1,1-dioxide derivatives. J.Med.Chem., 51, 2008
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1E96
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![BU of 1e96 by Molmil](/molmil-images/mine/1e96) | Structure of the Rac/p67phox complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NEUTROPHIL CYTOSOL FACTOR 2 (NCF-2) TPR DOMAIN, ... | Authors: | Lapouge, K, Smith, S.J.M, Walker, P.A, Gamblin, S.J, Smerdon, S.J, Rittinger, K. | Deposit date: | 2000-10-10 | Release date: | 2000-11-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the TPR domain of p67phox in complex with Rac.GTP. Mol.Cell, 6, 2000
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1RZZ
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![BU of 1rzz by Molmil](/molmil-images/mine/1rzz) | PHOTOSYNTHETIC REACTION CENTER DOUBLE MUTANT FROM RHODOBACTER SPHAEROIDES WITH ASP L213 REPLACED WITH ASN AND ARG M233 REPLACED WITH CYS IN THE CHARGE-NEUTRAL DQAQB STATE (TETRAGONAL FORM) | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (II) ION, ... | Authors: | Xu, Q, Axelrod, H.L, Abresch, E.C, Paddock, M.L, Okamura, M.Y, Feher, G. | Deposit date: | 2003-12-29 | Release date: | 2004-04-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-Ray Structure Determination of Three Mutants of the Bacterial Photosynthetic Reaction Centers from Rb. sphaeroides; Altered Proton Transfer Pathways. STRUCTURE, 12, 2004
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1EOD
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![BU of 1eod by Molmil](/molmil-images/mine/1eod) | CRYSTAL STRUCTURE OF THE N136D MUTANT OF A SHAKER T1 DOMAIN | Descriptor: | POTASSIUM CHANNEL KV1.1 | Authors: | Nanao, M.H, Cushman, S.J, Jahng, A.W, DeRubeis, D, Choe, S, Pfaffinger, P.J. | Deposit date: | 2000-03-22 | Release date: | 2000-05-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Voltage dependent activation of potassium channels is coupled to T1 domain structure. Nat.Struct.Biol., 7, 2000
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1J0I
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![BU of 1j0i by Molmil](/molmil-images/mine/1j0i) | Crystal structure of neopullulanase complex with panose | Descriptor: | alpha-D-glucopyranose-(1-6)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, neopullulanase | Authors: | Hondoh, H, Kuriki, T, Matsuura, Y. | Deposit date: | 2002-11-14 | Release date: | 2003-01-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Three-dimensional structure and substrate binding of Bacillus stearothermophilus neopullulanase J.Mol.Biol., 326, 2003
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2DS6
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![BU of 2ds6 by Molmil](/molmil-images/mine/2ds6) | Structure of the ZBD in the tetragonal crystal form | Descriptor: | ATP-dependent Clp protease ATP-binding subunit clpX, ZINC ION | Authors: | Park, E.Y, Lee, B.G, Hong, S.B, Song, H.K. | Deposit date: | 2006-06-22 | Release date: | 2007-02-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis of SspB-tail Recognition by the Zinc Binding Domain of ClpX. J.Mol.Biol., 367, 2007
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1EOF
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![BU of 1eof by Molmil](/molmil-images/mine/1eof) | CRYSTAL STRUCTURE OF THE N136A MUTANT OF A SHAKER T1 DOMAIN | Descriptor: | POTASSIUM CHANNEL KV1.1 | Authors: | Nanao, M.H, Cushman, S.J, Jahng, A.W, DeRubeis, D, Choe, S, Pfaffinger, P.J. | Deposit date: | 2000-03-22 | Release date: | 2000-05-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Voltage dependent activation of potassium channels is coupled to T1 domain structure. Nat.Struct.Biol., 7, 2000
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2TMN
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![BU of 2tmn by Molmil](/molmil-images/mine/2tmn) | CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN | Descriptor: | CALCIUM ION, N~2~-phosphono-L-leucinamide, Thermolysin, ... | Authors: | Tronrud, D.E, Monzingo, A.F, Matthews, B.W. | Deposit date: | 1987-06-29 | Release date: | 1989-01-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin. Eur.J.Biochem., 157, 1986
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1JEU
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![BU of 1jeu by Molmil](/molmil-images/mine/1jeu) | OLIGO-PEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH KEK | Descriptor: | OLIGO-PEPTIDE BINDING PROTEIN, PEPTIDE LYS GLU LYS, URANYL (VI) ION | Authors: | Tame, J, Wilkinson, A.J. | Deposit date: | 1996-07-03 | Release date: | 1997-05-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | The role of water in sequence-independent ligand binding by an oligopeptide transporter protein. Nat.Struct.Biol., 3, 1996
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1F0W
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![BU of 1f0w by Molmil](/molmil-images/mine/1f0w) | CRYSTAL STRUCTURE OF ORTHORHOMBIC LYSOZYME GROWN AT PH 6.5 | Descriptor: | LYSOZYME | Authors: | Biswal, B.K, Sukumar, N, Vijayan, M. | Deposit date: | 2000-05-17 | Release date: | 2000-06-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Hydration, mobility and accessibility of lysozyme: structures of a pH 6.5 orthorhombic form and its low-humidity variant and a comparative study involving 20 crystallographically independent molecules. Acta Crystallogr.,Sect.D, 56, 2000
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1JW4
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![BU of 1jw4 by Molmil](/molmil-images/mine/1jw4) | Structure of ligand-free maltodextrin-binding protein | Descriptor: | maltodextrin-binding protein | Authors: | Duan, X, Quiocho, F.A. | Deposit date: | 2001-09-02 | Release date: | 2002-01-30 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural evidence for a dominant role of nonpolar interactions in the binding of a transport/chemosensory receptor to its highly polar ligands. Biochemistry, 41, 2002
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2RHA
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1SCW
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![BU of 1scw by Molmil](/molmil-images/mine/1scw) | TOWARD BETTER ANTIBIOTICS: CRYSTAL STRUCTURE OF R61 DD-PEPTIDASE INHIBITED BY A NOVEL MONOCYCLIC PHOSPHATE INHIBITOR | Descriptor: | (2Z)-3-{[OXIDO(OXO)PHOSPHINO]OXY}-2-PHENYLACRYLATE, D-alanyl-D-alanine carboxypeptidase, GLYCEROL | Authors: | Silvaggi, N.R, Kaur, K, Adediran, S.A, Pratt, R.F, Kelly, J.A. | Deposit date: | 2004-02-12 | Release date: | 2004-06-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.13 Å) | Cite: | Toward Better Antibiotics: Crystallographic Studies of a Novel Class of DD-Peptidase/beta-Lactamase Inhibitors. Biochemistry, 43, 2004
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2DSU
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![BU of 2dsu by Molmil](/molmil-images/mine/2dsu) | Binding of chitin-like polysaccharide to protective signalling factor: Crystal structure of the complex formed between signalling protein from sheep (SPS-40) with a tetrasaccharide at 2.2 A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Chitinase-3-like protein 1, alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Srivastava, D.B, Ethayathulla, A.S, Kumar, J, Singh, N, Sharma, S, Kaur, P, Bhushan, A, Singh, T.P. | Deposit date: | 2006-07-07 | Release date: | 2006-07-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Carbohydrate binding properties and carbohydrate induced conformational switch in sheep secretory glycoprotein (SPS-40): crystal structures of four complexes of SPS-40 with chitin-like oligosaccharides J.Struct.Biol., 158, 2007
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