1SCW
TOWARD BETTER ANTIBIOTICS: CRYSTAL STRUCTURE OF R61 DD-PEPTIDASE INHIBITED BY A NOVEL MONOCYCLIC PHOSPHATE INHIBITOR
Summary for 1SCW
Entry DOI | 10.2210/pdb1scw/pdb |
Related | 1SDE |
Descriptor | D-alanyl-D-alanine carboxypeptidase, (2Z)-3-{[OXIDO(OXO)PHOSPHINO]OXY}-2-PHENYLACRYLATE, GLYCEROL, ... (4 entities in total) |
Functional Keywords | cyclic phosphate, antibiotic, peptidoglycan, penicillin binding protein, hydrolase |
Biological source | Streptomyces sp. |
Cellular location | Secreted: P15555 |
Total number of polymer chains | 1 |
Total formula weight | 38200.25 |
Authors | Silvaggi, N.R.,Kaur, K.,Adediran, S.A.,Pratt, R.F.,Kelly, J.A. (deposition date: 2004-02-12, release date: 2004-06-22, Last modification date: 2023-08-23) |
Primary citation | Silvaggi, N.R.,Kaur, K.,Adediran, S.A.,Pratt, R.F.,Kelly, J.A. Toward Better Antibiotics: Crystallographic Studies of a Novel Class of DD-Peptidase/beta-Lactamase Inhibitors. Biochemistry, 43:7046-7053, 2004 Cited by PubMed: 15170342DOI: 10.1021/bi049612c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.13 Å) |
Structure validation
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