1SDE

Toward Better Antibiotics: Crystal Structure Of D-Ala-D-Ala Peptidase inhibited by a novel bicyclic phosphate inhibitor

Summary for 1SDE

Entry DOI	10.2210/pdb1sde/pdb
Related	1MPL 1SCW
Descriptor	D-alanyl-D-alanine carboxypeptidase, 2-[(DIOXIDOPHOSPHINO)OXY]BENZOATE, GLYCEROL, ... (4 entities in total)
Functional Keywords	cyclic phosphate, peptidoglycan, penicillin binding protein, antibiotic, hydrolase
Biological source	Streptomyces sp.
Cellular location	Secreted: P15555
Total number of polymer chains	1
Total formula weight	37512.55
Authors	Silvaggi, N.R.,Kaur, K.,Adediran, S.A.,Pratt, R.F.,Kelly, J.A. (deposition date: 2004-02-13, release date: 2004-10-12, Last modification date: 2023-08-23)
Primary citation	Silvaggi, N.R.,Kaur, K.,Adediran, S.A.,Pratt, R.F.,Kelly, J.A. Toward better antibiotics: crystallographic studies of a novel class of DD-peptidase/beta-lactamase inhibitors Biochemistry, 43:7046-7053, 2004 Cited by PubMed: 15170342 DOI: 10.1021/bi049612c PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.15 Å)

Structure validation