2DSU

Binding of chitin-like polysaccharide to protective signalling factor: Crystal structure of the complex formed between signalling protein from sheep (SPS-40) with a tetrasaccharide at 2.2 A resolution

Replaces:  2AO8

Summary for 2DSU

• Entry DOI: 10.2210/pdb2dsu/pdb
• Related: 2DPE 2dsv 2dsw 2ESC
• Descriptor: Chitinase-3-like protein 1, alpha-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: sps-40, oligosaccharides, glycoprotein, signaling protein
• Biological source: Ovis aries (sheep)
• Total number of polymer chains: 1
• Total formula weight: 42192.28

Authors

Srivastava, D.B.,Ethayathulla, A.S.,Kumar, J.,Singh, N.,Sharma, S.,Kaur, P.,Bhushan, A.,Singh, T.P. (deposition date: 2006-07-07, release date: 2006-07-25, Last modification date: 2023-10-25)

• Primary citation: Srivastava, D.B.,Ethayathulla, A.S.,Kumar, J.,Somvanshi, R.K.,Sharma, S.,Dey, S.,Singh, T.P.; Carbohydrate binding properties and carbohydrate induced conformational switch in sheep secretory glycoprotein (SPS-40): crystal structures of four complexes of SPS-40 with chitin-like oligosaccharides; J.Struct.Biol., 158:255-266, 2007; PubMed: 17188513; DOI: 10.1016/j.jsb.2006.11.002

Experimental method

X-RAY DIFFRACTION (2.2 Å)