PDB: 238582 resultsInfo pagesStatus searchChemie searchBIRD

---

3KAT	Crystal Structure of the CARD domain of the human NLRP1 protein, Northeast Structural Genomics Consortium Target HR3486E Descriptor: NACHT, LRR and PYD domains-containing protein 1 Authors: Forouhar, F, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) Deposit date: 2009-10-19 Release date: 2009-10-27 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Northeast Structural Genomics Consortium Target HR3486E To be Published
7MRA	Crystal structure of the first bromodomain (BD1) of human BRD4 bound to NC-II-259 Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, N-[3-(2-methyl-1-oxo-1,2-dihydroisoquinolin-4-yl)phenyl]ethanesulfonamide Authors: Chan, A, Schonbrunn, E. Deposit date: 2021-05-07 Release date: 2022-08-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.16 Å) Cite: Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
7MRB	Crystal structure of the first bromodomain (BD1) of human BRD4 bound to NC-III-53 Descriptor: Bromodomain-containing protein 4, N-[4-(4-chlorophenoxy)-3-(2-methyl-1-oxo-1,2-dihydroisoquinolin-4-yl)phenyl]ethanesulfonamide Authors: Chan, A, Schonbrunn, E. Deposit date: 2021-05-07 Release date: 2022-08-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
7MRH	Crystal structure of the first bromodomain (BD1) of human BRDT bound to NC-II-259 Descriptor: Bromodomain testis-specific protein, N-[3-(2-methyl-1-oxo-1,2-dihydroisoquinolin-4-yl)phenyl]ethanesulfonamide Authors: Chan, A, Schonbrunn, E. Deposit date: 2021-05-07 Release date: 2022-08-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
7MRG	Crystal structure of the first bromodomain (BD1) of human BRDT bound to NC-II-153 Descriptor: 1,2-ETHANEDIOL, 2-methyl-4-[3-(2-oxopyrrolidin-1-yl)phenyl]isoquinolin-1(2H)-one, Bromodomain testis-specific protein, ... Authors: Chan, A, Schonbrunn, E. Deposit date: 2021-05-07 Release date: 2022-08-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
7MSS	Human E105Qa GTP-specific succinyl-CoA synthetase complexed with succinate, magnesium ion and CoA Descriptor: COENZYME A, GLYCEROL, MAGNESIUM ION, ... Authors: Huang, J, Fraser, M.E. Deposit date: 2021-05-12 Release date: 2022-10-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.75 Å) Cite: The structure of succinyl-CoA synthetase bound to the succinyl-phosphate intermediate clarifies the catalytic mechanism of ATP-citrate lyase Acta Crystallogr.,Sect.F, 78, 2022
7MSR	Human E105Qa GTP-specific succinyl-CoA synthetase complexed with succinyl-phosphate, magnesium ion and desulfo-coenzyme A Descriptor: 1,2-ETHANEDIOL, 4-oxo-4-(phosphonooxy)butanoic acid, DESULFO-COENZYME A, ... Authors: Huang, J, Fraser, M.E. Deposit date: 2021-05-12 Release date: 2022-10-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.58 Å) Cite: The structure of succinyl-CoA synthetase bound to the succinyl-phosphate intermediate clarifies the catalytic mechanism of ATP-citrate lyase Acta Crystallogr.,Sect.F, 78, 2022
3JAE	Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine-bound state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1 Authors: Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E. Deposit date: 2015-06-08 Release date: 2015-09-09 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Glycine receptor mechanism elucidated by electron cryo-microscopy. Nature, 526, 2015
7N2O	AS4.2-YEIH-HLA*B27 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... Authors: Yang, X, Jude, K.M, Garcia, K.C. Deposit date: 2021-05-29 Release date: 2022-12-07 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N2Q	AS4.3-YEIH-HLA*B27 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... Authors: Yang, X, Jude, K.M, Garcia, K.C. Deposit date: 2021-05-29 Release date: 2022-12-07 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N2S	AS3.1-PRPF3-HLA*B27 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... Authors: Yang, X, Jude, K.M, Garcia, K.C. Deposit date: 2021-05-29 Release date: 2022-12-07 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.37 Å) Cite: Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N2R	AS4.3-PRPF3-HLA*B27 Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, ... Authors: Yang, X, Jude, K.M, Garcia, K.C. Deposit date: 2021-05-29 Release date: 2022-12-07 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N2N	TCR-antigen complex AS4.2-PRPF3-HLA*B27 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... Authors: Yang, X, Jude, K.M, Garcia, K.C. Deposit date: 2021-05-29 Release date: 2022-12-07 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
3JVN	Crystal Structure of the acetyltransferase VF_1542 from Vibrio fischeri, Northeast Structural Genomics Consortium Target VfR136 Descriptor: Acetyltransferase, SULFATE ION Authors: Forouhar, F, Neely, H, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) Deposit date: 2009-09-17 Release date: 2009-09-29 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.61 Å) Cite: Northeast Structural Genomics Consortium Target VfR136 To be Published
7N2P	AS4.3-RNASEH2b-HLA*B27 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... Authors: Yang, X, Jude, K.M, Garcia, K.C. Deposit date: 2021-05-29 Release date: 2022-12-07 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N4O	Crystal structure of R20A human Galectin-7 mutant Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Galectin-7 Authors: Pham, N.T.H, Calmettes, C, Doucet, N. Deposit date: 2021-06-04 Release date: 2023-01-25 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Crystal structure of R20A human Galectin-7 mutant To Be Published
7N8G	Crystal structure of R20A-R22A human Galectin-7 mutant Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... Authors: Pham, N.T.H, Calmettes, C, Doucet, N. Deposit date: 2021-06-14 Release date: 2023-01-25 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of R20A human Galectin-7 mutant To Be Published
7MXR	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (r-2) Descriptor: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... Authors: Shi, Y, Beese, L.S. Deposit date: 2021-05-19 Release date: 2023-05-10 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.101 Å) Cite: Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7MXS	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (cr) Descriptor: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... Authors: Shi, Y, Beese, L.S. Deposit date: 2021-05-19 Release date: 2023-05-10 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.798 Å) Cite: Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7MXU	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' flap DNA (cf2) Descriptor: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*A)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... Authors: Shi, Y, Beese, L.S. Deposit date: 2021-05-19 Release date: 2023-05-10 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.042 Å) Cite: Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7MXV	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (ur) Descriptor: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... Authors: Shi, Y, Beese, L.S. Deposit date: 2021-05-19 Release date: 2023-05-10 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.211 Å) Cite: Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7MXT	Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (cmr) Descriptor: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ... Authors: Shi, Y, Beese, L.S. Deposit date: 2021-05-19 Release date: 2023-05-10 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.048 Å) Cite: Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities To Be Published
7N6C	Crystal structure of R22A human Galectin-7 mutant Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... Authors: Pham, N.T.H, Calmettes, C, Doucet, N. Deposit date: 2021-06-08 Release date: 2023-01-25 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of R20A human Galectin-7 mutant To Be Published
3JZY	Crystal structure of human Intersectin 2 C2 domain Descriptor: Intersectin 2, UNKNOWN ATOM OR ION Authors: Shen, Y, Tempel, W, Tong, Y, Li, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) Deposit date: 2009-09-24 Release date: 2009-10-06 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Crystal structure of human Intersectin 2 C2 domain To be Published
7N96	Crystal structure of D103A human Galectin-7 mutant Descriptor: GLYCEROL, Galectin-7 Authors: Pham, N.T.H, Calmettes, C, Doucet, N. Deposit date: 2021-06-16 Release date: 2023-01-25 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Crystal structure of D103A human Galectin-7 mutant To Be Published

<77787980818283848586878889909192>