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8YXW
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BU of 8yxw by Molmil
TRIP4 ASCH domain in complex with a 12bp dsDNA (5'-TGAGGTACCTCC-3')
Descriptor: Activating signal cointegrator 1, DNA (5'-D(*GP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*C)-3')
Authors:Ding, J, Yang, H, Hu, C.
Deposit date:2024-04-03
Release date:2024-06-26
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
Structure, 2024
8ZMS
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BU of 8zms by Molmil
Acetylcholine-bound VAChT
Descriptor: ACETYLCHOLINE, Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7
Authors:Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H.
Deposit date:2024-05-23
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insights into VAChT neurotransmitter recognition and inhibition.
Cell Res., 2024
4V9F
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BU of 4v9f by Molmil
The re-refined crystal structure of the Haloarcula marismortui large ribosomal subunit at 2.4 Angstrom resolution: more complete structure of the L7/L12 and L1 stalk, L5 and LX proteins
Descriptor: 23S Ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Gabdulkhakov, A.
Deposit date:2012-11-02
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:Revisiting the Haloarcula marismortui 50S ribosomal subunit model.
Acta Crystallogr.,Sect.D, 69, 2013
8XIP
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BU of 8xip by Molmil
Structure of Pasireotide-SSTR1 G protein complex
Descriptor: 004-DTR-LYS-TY5-PHE-A1D5E, G-alpha i, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Wang, Y, Xu, Y, Xu, H.E, Zhuang, Y.
Deposit date:2023-12-19
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
To Be Published
2XJC
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BU of 2xjc by Molmil
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with guanosine monophosphate and diadenosine tetraphosphate
Descriptor: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, ...
Authors:Wallden, K, Nordlund, P.
Deposit date:2010-07-03
Release date:2011-03-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II
J.Mol.Biol., 408, 2011
9C4O
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BU of 9c4o by Molmil
Cryo-EM structure of PqqU with ligand PQQ
Descriptor: CALCIUM ION, PYRROLOQUINOLINE QUINONE, Pyrroloquinoline quinone transporter
Authors:Munder, F, Venugopal, H, Grinter, R.
Deposit date:2024-06-04
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (1.99 Å)
Cite:High-affinity PQQ import is widespread in Gram-negative bacteria.
To Be Published
9C6P
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BU of 9c6p by Molmil
X-ray crystal structure of AmpC beta-lactamase with inhibitor
Descriptor: 3-chloro-N-(5-chloro-2-methyl-1,3-benzothiazol-6-yl)-2-hydroxybenzene-1-sulfonamide, AmpC Beta-lactamase
Authors:Liu, F, Shoichet, B.K.
Deposit date:2024-06-08
Release date:2024-06-19
Method:X-RAY DIFFRACTION (1.663 Å)
Cite:Improved correlations with score, hit-rate, and affinity as docking library and testing scale increase
To Be Published
6ZJX
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BU of 6zjx by Molmil
Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant D207A in complex with saccharose
Descriptor: ACETATE ION, Beta-galactosidase, MALONATE ION, ...
Authors:Rutkiewicz, M, Bujacz, A, Bujacz, G.
Deposit date:2020-06-29
Release date:2020-08-05
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Mapping the Transglycosylation Relevant Sites of Cold-Adapted beta-d-Galactosidase fromArthrobactersp. 32cB.
Int J Mol Sci, 21, 2020
8ZWK
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BU of 8zwk by Molmil
Polyadenylic acid bound alpha-synuclein fibril Polymorph 2
Descriptor: Alpha-synuclein, RNA (5'-R(P*AP*AP*A)-3')
Authors:Tao, Y.Q, Liu, C, Li, D.
Deposit date:2024-06-13
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Polyadenylic acid bound alpha-synuclein fibril Polymorph 2
To Be Published
8ZWJ
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BU of 8zwj by Molmil
Polyadenylic acid bound alpha-synuclein fibril Polymorph 1
Descriptor: Alpha-synuclein, RNA (5'-R(P*AP*AP*A)-3')
Authors:Tao, Y.Q, Liu, C, Li, D.
Deposit date:2024-06-13
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Polyadenylic acid bound alpha-synuclein fibril Polymorph 1
To Be Published
8ZJD
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BU of 8zjd by Molmil
Cryo-EM structure of kisspeptin receptor bound to KP-10
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(q) subunit alpha, ...
Authors:Shen, S, Liu, H, Xu, H.E.
Deposit date:2024-05-14
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Cryo-EM structure of kisspeptin receptor bound to KP-10
To Be Published
8XIO
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BU of 8xio by Molmil
Structure of L797591-SSTR1 G protein complex
Descriptor: (2~{S})-~{N}-[(4~{S})-6-azanyl-2,2,4-trimethyl-hexyl]-3-naphthalen-1-yl-2-[[2-phenylethyl(2-pyridin-2-ylethyl)carbamoyl]amino]propanamide, G-alpha-i, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Wang, Y, Xu, Y, Xu, H.E, Zhuang, Y.
Deposit date:2023-12-19
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
To Be Published
8XYZ
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BU of 8xyz by Molmil
The structure of fox ACE2 and PT RBD complex
Descriptor: Angiotensin-converting enzyme, Signal peptide, Spike protein S1, ...
Authors:sun, J.Q.
Deposit date:2024-01-20
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:The structure of fox ACE2/PT RBD complex
To Be Published
1VYN
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BU of 1vyn by Molmil
STRUCTURE AND NUCLEIC ACID BINDING OF THE DROSOPHILA ARGONAUTE2 PAZ DOMAIN
Descriptor: ARGONAUTE2
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2004-05-03
Release date:2004-05-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain.
Nature, 426, 2003
3GLB
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BU of 3glb by Molmil
Crystal structure of the effector binding domain of a CATM variant (R156H)
Descriptor: (2Z,4Z)-HEXA-2,4-DIENEDIOIC ACID, GLYCEROL, HTH-type transcriptional regulator catM, ...
Authors:Ezezika, O.C, Craven, S.H, Neidle, E.L, Momany, C.
Deposit date:2009-03-11
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Inducer responses of BenM, a LysR-type transcriptional regulator from Acinetobacter baylyi ADP1.
Mol.Microbiol., 72, 2009
2XJE
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BU of 2xje by Molmil
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with uridine 5'-monophosphate and adenosine triphosphate
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, ...
Authors:Wallden, K, Nordlund, P.
Deposit date:2010-07-04
Release date:2011-03-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II
J.Mol.Biol., 408, 2011
5VOD
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BU of 5vod by Molmil
Crystal structure of HCMV Pentamer in complex with neutralizing antibody 9I6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ...
Authors:Malito, E, Chandramouli, S.
Deposit date:2017-05-02
Release date:2017-07-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (5.9 Å)
Cite:Structural basis for potent antibody-mediated neutralization of human cytomegalovirus.
Sci Immunol, 2, 2017
2FQG
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BU of 2fqg by Molmil
Crystal Structures of E. coli Laccase CueO under different copper binding situations
Descriptor: Blue copper oxidase cueO, CITRIC ACID, COPPER (II) ION, ...
Authors:Li, X, Wei, Z, Zhang, M, Teng, M, Gong, W.
Deposit date:2006-01-18
Release date:2007-01-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of E. coli laccase CueO at different copper concentrations.
Biochem.Biophys.Res.Commun., 354, 2007
4NZI
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BU of 4nzi by Molmil
Crystal structure of murine neuroglobin mutant V140W
Descriptor: Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Avella, G, Savino, C, Vallone, B.
Deposit date:2013-12-12
Release date:2014-06-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Engineering the internal cavity of neuroglobin demonstrates the role of the haem-sliding mechanism.
Acta Crystallogr.,Sect.D, 70, 2014
9ILB
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BU of 9ilb by Molmil
HUMAN INTERLEUKIN-1 BETA
Descriptor: PROTEIN (HUMAN INTERLEUKIN-1 BETA)
Authors:Yu, B, Blaber, M, Gronenborn, A.M, Clore, G.M, Caspar, D.L.D.
Deposit date:1998-10-22
Release date:1999-01-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Disordered water within a hydrophobic protein cavity visualized by x-ray crystallography.
Proc.Natl.Acad.Sci.USA, 96, 1999
9LDB
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BU of 9ldb by Molmil
DESIGN AND SYNTHESIS OF NEW ENZYMES BASED ON THE LACTATE DEHYDROGENASE FRAMEWORK
Descriptor: LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID, ...
Authors:Dunn, C.R, Holbrook, J.J, Muirhead, H.
Deposit date:1991-11-26
Release date:1993-10-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Design and synthesis of new enzymes based on the lactate dehydrogenase framework.
Philos.Trans.R.Soc.London,Ser.B, 332, 1991
9LDT
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BU of 9ldt by Molmil
DESIGN AND SYNTHESIS OF NEW ENZYMES BASED ON THE LACTATE DEHYDROGENASE FRAMEWORK
Descriptor: LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID, ...
Authors:Dunn, C.R, Holbrook, J.J, Muirhead, H.
Deposit date:1991-11-26
Release date:1993-10-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and synthesis of new enzymes based on the lactate dehydrogenase framework.
Philos.Trans.R.Soc.London,Ser.B, 332, 1991
9LPR
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BU of 9lpr by Molmil
STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Bone, R, Agard, D.A.
Deposit date:1991-08-05
Release date:1993-01-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for broad specificity in alpha-lytic protease mutants.
Biochemistry, 30, 1991
3GSY
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BU of 3gsy by Molmil
Structure of berberine bridge enzyme in complex with dehydroscoulerine
Descriptor: 2,9-dihydroxy-3,10-dimethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium, 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Winkler, A, Macheroux, P, Gruber, K.
Deposit date:2009-03-27
Release date:2009-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Berberine bridge enzyme catalyzes the six electron oxidation of (S)-reticuline to dehydroscoulerine.
Phytochemistry, 70, 2009
5VED
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BU of 5ved by Molmil
PAK4 kinase domain in complex with Staurosporine
Descriptor: STAUROSPORINE, Serine/threonine-protein kinase PAK 4
Authors:Zhang, E.Y, Ha, B.H, Boggon, T.J.
Deposit date:2017-04-04
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:PAK4 crystal structures suggest unusual kinase conformational movements.
Biochim. Biophys. Acta, 1866, 2018

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数据于2024-07-10公开中

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