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2JA6	CPD lesion containing RNA Polymerase II elongation complex B Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TP*TTP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ... Authors: Brueckner, F, Hennecke, U, Carell, T, Cramer, P. Deposit date: 2006-11-23 Release date: 2007-02-20 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (4 Å) Cite: CPD damage recognition by transcribing RNA polymerase II. Science, 315, 2007
2JA7	CPD lesion containing RNA Polymerase II elongation complex C Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TP*TP*TTP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ... Authors: Brueckner, F, Hennecke, U, Carell, T, Cramer, P. Deposit date: 2006-11-23 Release date: 2007-02-20 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Cpd Damage Recognition by Transcribing RNA Polymerase II. Science, 315, 2007
4BY1	elongating RNA Polymerase II-Bye1 TLD complex soaked with AMPCPP Descriptor: 5'-D(*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP *TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*AP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ... Authors: Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. Deposit date: 2013-07-17 Release date: 2013-09-11 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue Proc.Natl.Acad.Sci.USA, 110, 2013
4BY7	elongating RNA Polymerase II-Bye1 TLD complex Descriptor: , 5'-D(*DAP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*DTP)-3', 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. Deposit date: 2013-07-18 Release date: 2013-09-11 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
2B63	Complete RNA Polymerase II-RNA inhibitor complex Descriptor: 31-MER, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ... Authors: Kettenberger, H, Eisenfuehr, A, Brueckner, F, Theis, M, Famulok, M, Cramer, P. Deposit date: 2005-09-30 Release date: 2005-12-06 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs Nat.Struct.Mol.Biol., 13, 2006
3PO3	Arrested RNA Polymerase II reactivation intermediate Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, DNA non-template strand, ... Authors: Cheung, A.C.M, Cramer, P. Deposit date: 2010-11-21 Release date: 2011-03-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural basis of RNA polymerase II backtracking, arrest and reactivation. Nature, 471, 2011
3PO2	Arrested RNA Polymerase II elongation complex Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Cheung, A.C.M, Cramer, P. Deposit date: 2010-11-21 Release date: 2011-03-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural basis of RNA polymerase II backtracking, arrest and reactivation. Nature, 471, 2011
4PZ6	PCE1 guanylyltransferase bound to SER2/SER5 phosphorylated RNA pol II CTD Descriptor: DNA-directed RNA polymerase II subunit rpb1, GUANOSINE, mRNA-capping enzyme subunit alpha Authors: Doamekpor, S.K, Lima, C.D. Deposit date: 2014-03-28 Release date: 2014-06-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.406 Å) Cite: How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes. Genes Dev., 28, 2014
7ZX7	Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. Deposit date: 2022-05-20 Release date: 2022-11-30 Last modified: 2022-12-28 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
7ZWD	Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. Deposit date: 2022-05-19 Release date: 2022-11-30 Last modified: 2022-12-28 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
7ZX8	Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. Deposit date: 2022-05-20 Release date: 2022-12-07 Last modified: 2022-12-28 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
7Z42	Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 2B Descriptor: DNA-directed RNA polymerase II subunit RPB1, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Cusack, S, Drncova, P. Deposit date: 2022-03-03 Release date: 2022-05-18 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.418 Å) Cite: Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD. Plos Pathog., 18, 2022
7OKX	Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite structure) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... Authors: Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. Deposit date: 2021-05-18 Release date: 2021-07-14 Last modified: 2021-09-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Allosteric transcription stimulation by RNA polymerase II super elongation complex. Mol.Cell, 81, 2021
7OKY	Structure of active transcription elongation complex Pol II-DSIF-ELL2-EAF1(composite structure) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... Authors: Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. Deposit date: 2021-05-18 Release date: 2021-07-14 Last modified: 2021-09-01 Method: ELECTRON MICROSCOPY (4.14 Å) Cite: Allosteric transcription stimulation by RNA polymerase II super elongation complex. Mol.Cell, 81, 2021
7OL0	Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... Authors: Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. Deposit date: 2021-05-18 Release date: 2021-07-14 Last modified: 2021-09-01 Method: ELECTRON MICROSCOPY (3 Å) Cite: Allosteric transcription stimulation by RNA polymerase II super elongation complex. Mol.Cell, 81, 2021
6BM2	Pol II elongation complex with an abasic lesion at i-1 position Descriptor: DNA (5'-D(P*CP*AP*(3DR)P*CP*TP*CP*TP*TP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Wang, W, Wang, D. Deposit date: 2017-11-13 Release date: 2018-02-28 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.403 Å) Cite: Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BLO	Pol II elongation complex with an abasic lesion at i+1 position Descriptor: DNA (5'-D(P*AP*(3DR)P*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Wang, W, Wang, D. Deposit date: 2017-11-10 Release date: 2018-02-28 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.401 Å) Cite: Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BM4	Pol II elongation complex with an abasic lesion at i-1 position,soaking UMPNPP Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, DNA (5'-D(P*CP*AP*(3DR)P*CP*TP*CP*TP*TP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... Authors: Wang, W, Wang, D. Deposit date: 2017-11-13 Release date: 2018-02-28 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.951 Å) Cite: Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BLP	Pol II elongation complex with an abasic lesion at i+1 position, soaking AMPCPP Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (5'-D(P*AP*(3DR)P*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... Authors: Wang, W, Wang, D. Deposit date: 2017-11-11 Release date: 2018-02-28 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.203 Å) Cite: Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BQF	Pol II elongation complex with 'dT-AP' at i+1, i-1 position Descriptor: DNA (5'-D(P*CP*TP*(3DR)P*CP*TP*CP*TP*TP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Wang, W, Wang, D. Deposit date: 2017-11-27 Release date: 2018-02-28 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.35 Å) Cite: Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5W4U	Pol II elongation complex with an N6-methyladenine-containing template Descriptor: 14mer non-template DNA, 29mer template DNA, 9mer RNA, ... Authors: Wang, W, Wang, D. Deposit date: 2017-06-13 Release date: 2018-06-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing. J.Am.Chem.Soc., 139, 2017
5W51	Pol II elongation complex with an N6-methyladenine-containing template and a matched UMPNPP Descriptor: 14mer non-template DNA, 29mer template DNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... Authors: Wang, W, Wang, D. Deposit date: 2017-06-13 Release date: 2018-06-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.404 Å) Cite: Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing. J.Am.Chem.Soc., 139, 2017
3D9K	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II Descriptor: CTD-PEPTIDE, RNA-binding protein 16, SULFATE ION Authors: Becker, R, Loll, B, Meinhart, A. Deposit date: 2008-05-27 Release date: 2008-06-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Snapshots of the RNA Processing Factor SCAF8 Bound to Different Phosphorylated Forms of the Carboxyl-terminal Domain of RNA Polymerase II. J.Biol.Chem., 283, 2008
3D9P	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II Descriptor: CTD-PEPTIDE, RNA-binding protein 16, SULFATE ION Authors: Becker, R, Loll, B, Meinhart, A. Deposit date: 2008-05-27 Release date: 2008-06-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Snapshots of the RNA Processing Factor SCAF8 Bound to Different Phosphorylated Forms of the Carboxyl-terminal Domain of RNA Polymerase II. J.Biol.Chem., 283, 2008
3D9O	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II Descriptor: AMMONIUM ION, CTD-PEPTIDE, RNA-binding protein 16, ... Authors: Becker, R, Loll, B, Meinhart, A. Deposit date: 2008-05-27 Release date: 2008-06-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Snapshots of the RNA Processing Factor SCAF8 Bound to Different Phosphorylated Forms of the Carboxyl-terminal Domain of RNA Polymerase II. J.Biol.Chem., 283, 2008

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