3HOY

Complete RNA polymerase II elongation complex VI

Summary for 3HOY

Related3HOU 3HOV 3HOW 3HOX 3HOZ
DescriptorDNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... (17 entities in total)
Functional Keywordsrna polymerase ii, metal-binding, transcription bubble, elongation complex, transcription, dna-rna mismatch, rna fraying, dna-binding, dna-directed rna polymerase, isopeptide bond, magnesium, nucleotidyltransferase, nucleus, phosphoprotein, transferase, ubl conjugation, zinc, zinc-finger, polymorphism, cytoplasm, dna damage, dna repair, mrna processing, transferase-dna-rna hybrid complex, transferase/dna/rna hybrid
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
Cellular locationNucleus P04050 P08518 P16370 P20433 P20434 P34087 P20436 P27999 P38902
Cytoplasm P20435
Nucleus, nucleolus P22139 P40422
Total number of polymer chains15
Total molecular weight549718.26
Authors
Sydow, J.F.,Brueckner, F.,Cheung, A.C.M.,Damsma, G.E.,Dengl, S.,Lehmann, E.,Vassylyev, D.,Cramer, P. (deposition date: 2009-06-03, release date: 2009-07-28, Last modification date: 2011-07-13)
Primary citation
Sydow, J.F.,Brueckner, F.,Cheung, A.C.M.,Damsma, G.E.,Dengl, S.,Lehmann, E.,Vassylyev, D.,Cramer, P.
Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Mol.Cell, 34:710-721, 2009
PubMed: 19560423 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2009.06.002
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.256528.7%10.6%3.8%0.61MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution