Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

2BF7
DownloadVisualize
BU of 2bf7 by Molmil
Leishmania major pteridine reductase 1 in complex with NADP and biopterin
Descriptor: 1,2-ETHANEDIOL, 7,8-DIHYDROBIOPTERIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Schuettelkopf, A.W, Hunter, W.N.
Deposit date:2004-12-06
Release date:2005-08-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Leishmania Major Pteridine Reductase Complexes Reveal the Active Site Features Important for Ligand Binding and to Guide Inhibitor Design
J.Mol.Biol., 352, 2005
2BFA
DownloadVisualize
BU of 2bfa by Molmil
Leishmania major pteridine reductase 1 in complex with NADP and CB3717
Descriptor: 1,2-ETHANEDIOL, 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Schuettelkopf, A.W, Hunter, W.N.
Deposit date:2004-12-06
Release date:2005-08-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of Leishmania Major Pteridine Reductase Complexes Reveal the Active Site Features Important for Ligand Binding and to Guide Inhibitor Design
J.Mol.Biol., 352, 2005
2BFP
DownloadVisualize
BU of 2bfp by Molmil
Leishmania major pteridine reductase 1 in complex with NADP and tetrahydrobiopterin
Descriptor: 1,2-ETHANEDIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Schuettelkopf, A.W, Hunter, W.N.
Deposit date:2004-12-10
Release date:2005-08-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structures of Leishmania Major Pteridine Reductase Complexes Reveal the Active Site Features Important for Ligand Binding and to Guide Inhibitor Design
J.Mol.Biol., 352, 2005
5XN2
DownloadVisualize
BU of 5xn2 by Molmil
HIV-1 reverse transcriptase Q151M:DNA:dGTP ternary complex
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 38-MER DNA aptamer, GLYCEROL, ...
Authors:Yasutake, Y, Tamura, N, Hayashi, H, Maeda, K.
Deposit date:2017-05-17
Release date:2018-02-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.381 Å)
Cite:HIV-1 with HBV-associated Q151M substitution in RT becomes highly susceptible to entecavir: structural insights into HBV-RT inhibition by entecavir.
Sci Rep, 8, 2018
2QX0
DownloadVisualize
BU of 2qx0 by Molmil
Crystal Structure of Yersinia pestis HPPK (Ternary Complex)
Descriptor: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
Authors:Blaszczyk, J, Cherry, S, Tropea, J.E, Waugh, D.S, Ji, X.
Deposit date:2007-08-10
Release date:2007-10-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and activity of Yersinia pestis 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as a novel target for the development of antiplague therapeutics.
Acta Crystallogr.,Sect.D, 63, 2007
8BMR
DownloadVisualize
BU of 8bmr by Molmil
Cryo-EM structure of the wild-type solitary ECF module in MSP2N2 lipid nanodiscs in the ATPase open and nucleotide-free conformation
Descriptor: Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT
Authors:Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J.
Deposit date:2022-11-10
Release date:2023-08-02
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Expulsion mechanism of the substrate-translocating subunit in ECF transporters.
Nat Commun, 14, 2023
3GN1
DownloadVisualize
BU of 3gn1 by Molmil
Structure of Pteridine Reductase 1 (PTR1) from TRYPANOSOMA BRUCEI in ternary complex with cofactor (NADP+) and inhibitor (DDD00067116)
Descriptor: 1H-benzimidazol-2-amine, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Tulloch, L.B, Brenk, R, Hunter, W.N.
Deposit date:2009-03-16
Release date:2009-12-29
Last modified:2011-09-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening.
J.Med.Chem., 52, 2009
5H1T
DownloadVisualize
BU of 5h1t by Molmil
Complex structure of TRIM24 PHD-bromodomain and inhibitor 1
Descriptor: DIMETHYL SULFOXIDE, Transcription intermediary factor 1-alpha, ZINC ION, ...
Authors:Liu, J.
Deposit date:2016-10-11
Release date:2017-02-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network
FEBS J., 284, 2017
1OUD
DownloadVisualize
BU of 1oud by Molmil
CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V121A MUTANT
Descriptor: LYSOZYME, SODIUM ION
Authors:Takano, K, Yamagata, Y, Fujii, S, Yutani, K.
Deposit date:1996-08-23
Release date:1997-02-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Contribution of the hydrophobic effect to the stability of human lysozyme: calorimetric studies and X-ray structural analyses of the nine valine to alanine mutants.
Biochemistry, 36, 1997
3LU8
DownloadVisualize
BU of 3lu8 by Molmil
Human serum albumin in complex with compound 3
Descriptor: N-[5-(5-{[(2,4-dimethyl-1,3-thiazol-5-yl)sulfonyl]amino}-6-fluoropyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]acetamide, Serum albumin
Authors:Buttar, D, Colclough, N, Gerhardt, S, MacFaul, P.A, Phillips, S.D, Plowright, A, Whittamore, P, Tam, K, Maskos, K, Steinbacher, S, Steuber, H.
Deposit date:2010-02-17
Release date:2010-10-27
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions
Bioorg.Med.Chem., 18, 2010
5MVP
DownloadVisualize
BU of 5mvp by Molmil
Crystal structure of an A-DNA dodecamer containing the GGGCCC motif
Descriptor: DNA, POTASSIUM ION
Authors:Hardwick, J.S, Ptchelkine, D, Phillips, S.E.V, Brown, T.
Deposit date:2017-01-17
Release date:2017-05-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.606 Å)
Cite:5-Formylcytosine does not change the global structure of DNA.
Nat. Struct. Mol. Biol., 24, 2017
5TVP
DownloadVisualize
BU of 5tvp by Molmil
SUMO2 bound to Mouse Tdp2 catalytic domain with a 5'-phosphorylated DNA ternary complex
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), ...
Authors:Schellenberg, M.J, Williams, R.S.
Deposit date:2016-11-09
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links.
Science, 357, 2017
5MYJ
DownloadVisualize
BU of 5myj by Molmil
Structure of 70S ribosome from Lactococcus lactis
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Franken, L.E, Oostergetel, G.T, Pijning, T, Puri, P, Boekema, E.J, Poolman, B, Guskov, A.
Deposit date:2017-01-26
Release date:2017-10-11
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:A general mechanism of ribosome dimerization revealed by single-particle cryo-electron microscopy.
Nat Commun, 8, 2017
5MBA
DownloadVisualize
BU of 5mba by Molmil
BINDING MODE OF AZIDE TO FERRIC APLYSIA LIMACINA MYOGLOBIN. CRYSTALLOGRAPHIC ANALYSIS AT 1.9 ANGSTROMS RESOLUTION
Descriptor: AZIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Bolognesi, M, Onesti, S, Gatti, G, Coda, A, Ascenzi, P, Brunori, M.
Deposit date:1991-01-14
Release date:1992-07-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Binding mode of azide to ferric Aplysia limacina myoglobin. Crystallographic analysis at 1.9 A resolution.
J.Mol.Recog., 4, 1991
3LOY
DownloadVisualize
BU of 3loy by Molmil
Crystal structure of a Copper-containing benzylamine oxidase from Hansenula Polymorpha
Descriptor: COPPER (II) ION, GLYCEROL, L(+)-TARTARIC ACID, ...
Authors:Klema, V.J, Johnson, B.J, Wilmot, C.M.
Deposit date:2010-02-04
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kinetic and structural analysis of substrate specificity in two copper amine oxidases from Hansenula polymorpha.
Biochemistry, 49, 2010
5TUV
DownloadVisualize
BU of 5tuv by Molmil
Crystal structure of the E2F5-DP1-p107 ternary complex
Descriptor: Retinoblastoma-like protein 1, Transcription factor DP1, Transcription factor E2F5
Authors:Liban, T.J, Tripathi, S.M, Rubin, S.M.
Deposit date:2016-11-07
Release date:2017-05-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Conservation and divergence of C-terminal domain structure in the retinoblastoma protein family.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1OUG
DownloadVisualize
BU of 1oug by Molmil
CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V2A MUTANT
Descriptor: LYSOZYME, SODIUM ION
Authors:Takano, K, Yamagata, Y, Fujii, S, Yutani, K.
Deposit date:1996-08-23
Release date:1997-02-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Contribution of the hydrophobic effect to the stability of human lysozyme: calorimetric studies and X-ray structural analyses of the nine valine to alanine mutants.
Biochemistry, 36, 1997
3LU7
DownloadVisualize
BU of 3lu7 by Molmil
Human serum albumin in complex with compound 2
Descriptor: 4-[(1R,2R)-2-{[(5-fluoro-1H-indol-2-yl)carbonyl]amino}-2,3-dihydro-1H-inden-1-yl]butanoic acid, PHOSPHATE ION, Serum albumin
Authors:Buttar, D, Colclough, N, Gerhardt, S, MacFaul, P.A, Phillips, S.D, Plowright, A, Whittamore, P, Tam, K, Maskos, K, Steinbacher, S, Steuber, H.
Deposit date:2010-02-17
Release date:2010-10-27
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions
Bioorg.Med.Chem., 18, 2010
6RQG
DownloadVisualize
BU of 6rqg by Molmil
P46, an immunodominant surface protein from Mycoplasma hyopneumoniae
Descriptor: 46 kDa surface antigen, SODIUM ION
Authors:Guasch, A, Fita, I.
Deposit date:2019-05-15
Release date:2019-11-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of P46, an immunodominant surface 58 protein from Mycoplasma hyopneumoniae:interaction with a monoclonal antibody
Acta Crys Section D, D76, 2020
2CAU
DownloadVisualize
BU of 2cau by Molmil
CANAVALIN FROM JACK BEAN
Descriptor: PROTEIN (CANAVALIN)
Authors:Ko, T.-P, Day, J, Macpherson, A.
Deposit date:1998-11-20
Release date:1998-11-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The refined structure of canavalin from jack bean in two crystal forms at 2.1 and 2.0 A resolution.
Acta Crystallogr.,Sect.D, 56, 2000
5GIJ
DownloadVisualize
BU of 5gij by Molmil
Crystal structure of TDR-TDIF complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat receptor-like protein kinase TDR, ...
Authors:Morita, J, Kato, K, Ishitani, R, Nishimasu, H, Nureki, O.
Deposit date:2016-06-23
Release date:2016-08-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the plant receptor-like kinase TDR in complex with the TDIF peptide
Nat Commun, 7, 2016
1P32
DownloadVisualize
BU of 1p32 by Molmil
CRYSTAL STRUCTURE OF HUMAN P32, A DOUGHNUT-SHAPED ACIDIC MITOCHONDRIAL MATRIX PROTEIN
Descriptor: MITOCHONDRIAL MATRIX PROTEIN, SF2P32
Authors:Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M.
Deposit date:1998-11-02
Release date:1999-04-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix protein.
Proc.Natl.Acad.Sci.USA, 96, 1999
1OQN
DownloadVisualize
BU of 1oqn by Molmil
Crystal structure of the phosphotyrosine binding domain (PTB) of mouse Disabled 1 (Dab1)
Descriptor: Alzheimer's disease amyloid A4 protein homolog, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Disabled homolog 1
Authors:Yun, M, Keshvara, L, Park, C.-G, Zhang, Y.-M, Dickerson, J.B, Zheng, J, Rock, C.O, Curran, T, Park, H.-W.
Deposit date:2003-03-10
Release date:2003-08-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of the Dab homology domains of mouse disabled 1 and 2
J.Biol.Chem., 278, 2003
1ORH
DownloadVisualize
BU of 1orh by Molmil
Structure of the Predominant Protein Arginine Methyltransferase PRMT1
Descriptor: GLYCEROL, Protein arginine N-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Zhang, X, Cheng, X.
Deposit date:2003-03-13
Release date:2003-08-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structure of the Predominant Protein Arginine Methyltransferase PRMT1 and Analysis of Its Binding to Substrate Peptides
Structure, 11, 2003
6RNW
DownloadVisualize
BU of 6rnw by Molmil
The crystal structure of Thermosynechococcus elongatus protochlorophyllide oxidoreductase (POR) in complex with NADP.
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-protochlorophyllide oxidoreductase
Authors:Levy, C.W.
Deposit date:2019-05-09
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis.
Nature, 574, 2019

232829

数据于2025-03-12公开中

PDB statisticsPDBj update infoContact PDBjnumon