2QX0

Crystal Structure of Yersinia pestis HPPK (Ternary Complex)

Summary for 2QX0

• Entry DOI: 10.2210/pdb2qx0/pdb
• Related: 1Q0N
• Descriptor: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, MAGNESIUM ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... (5 entities in total)
• Functional Keywords: 3-layered alpha-bata-alpha fold, homodimer, ternary complex, kinase, transferase
• Biological source: Yersinia pestis
• Total number of polymer chains: 2
• Total formula weight: 37513.66

Authors

Blaszczyk, J.,Cherry, S.,Tropea, J.E.,Waugh, D.S.,Ji, X. (deposition date: 2007-08-10, release date: 2007-10-23, Last modification date: 2023-11-15)

• Primary citation: Blaszczyk, J.,Li, Y.,Cherry, S.,Alexandratos, J.,Wu, Y.,Shaw, G.,Tropea, J.E.,Waugh, D.S.,Yan, H.,Ji, X.; Structure and activity of Yersinia pestis 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as a novel target for the development of antiplague therapeutics.; Acta Crystallogr.,Sect.D, 63:1169-1177, 2007; PubMed: 18007032; DOI: 10.1107/S0907444907047452

Experimental method

X-RAY DIFFRACTION (1.8 Å)