5TVP

SUMO2 bound to Mouse Tdp2 catalytic domain with a 5'-phosphorylated DNA ternary complex

Summary for 5TVP

• Entry DOI: 10.2210/pdb5tvp/pdb
• Related: 1WM2 4GZ1 5TVQ
• Descriptor: Tyrosyl-DNA phosphodiesterase 2, DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), Small ubiquitin-related modifier 2, ... (7 entities in total)
• Functional Keywords: hydrolase, dna repair, endonuclease/exonuclease/phosphatase (eep) domain, hydrolase-dna complex, hydrolase/dna
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 17
• Total formula weight: 264101.73

Authors

Schellenberg, M.J.,Williams, R.S. (deposition date: 2016-11-09, release date: 2017-10-11, Last modification date: 2023-10-04)

• Primary citation: Schellenberg, M.J.,Lieberman, J.A.,Herrero-Ruiz, A.,Butler, L.R.,Williams, J.G.,Munoz-Cabello, A.M.,Mueller, G.A.,London, R.E.,Cortes-Ledesma, F.,Williams, R.S.; ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links.; Science, 357:1412-1416, 2017; PubMed: 28912134; DOI: 10.1126/science.aam6468

Experimental method

X-RAY DIFFRACTION (2.399 Å)