1OR7
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![BU of 1or7 by Molmil](/molmil-images/mine/1or7) | Crystal Structure of Escherichia coli sigmaE with the Cytoplasmic Domain of its Anti-sigma RseA | Descriptor: | RNA polymerase sigma-E factor, Sigma-E factor negative regulatory protein | Authors: | Campbell, E.A, Tupy, J.L, Gruber, T.M, Wang, S, Sharp, M.M, Gross, C.A, Darst, S.A. | Deposit date: | 2003-03-12 | Release date: | 2003-04-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA. Mol.Cell, 11, 2003
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7NS3
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![BU of 7ns3 by Molmil](/molmil-images/mine/7ns3) | Substrate receptor scaffolding module of yeast Chelator-GID SR4 E3 ubiquitin ligase bound to Fbp1 substrate | Descriptor: | BJ4_G0018240.mRNA.1.CDS.1, Fructose-bisphosphatase, Glucose-induced degradation protein 8, ... | Authors: | Sherpa, D, Chrustowicz, J, Prabu, J.R, Schulman, B.A. | Deposit date: | 2021-03-05 | Release date: | 2021-05-05 | Last modified: | 2021-07-07 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme. Mol.Cell, 81, 2021
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4GG9
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![BU of 4gg9 by Molmil](/molmil-images/mine/4gg9) | |
2ISP
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![BU of 2isp by Molmil](/molmil-images/mine/2isp) | Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-methylene triphosphate | Descriptor: | 2'-DEOXY-5'-O-(HYDROXY{[HYDROXY(PHOSPHONOMETHYL)PHOSPHORYL]OXY}PHOSPHORYL)GUANOSINE, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ... | Authors: | Sucato, C.A, Upton, T.G, Kashemirov, B.A, Martinek, V, Xiang, Y, Beard, W.A. | Deposit date: | 2006-10-18 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Modifying the beta,gamma Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of DNA Polymerase beta. Biochemistry, 46, 2007
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2ISO
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![BU of 2iso by Molmil](/molmil-images/mine/2iso) | Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-difluoromethylene triphosphate | Descriptor: | 2'-DEOXY-5'-O-[({[DIFLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL}OXY)(HYDROXY)PHOSPHORYL]GUANOSINE, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ... | Authors: | Sucato, C.A, Upton, T.G, Kashemirov, B.A, Martinek, V, Xiang, Y, Beard, W.A. | Deposit date: | 2006-10-18 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Modifying the beta,gamma Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of DNA Polymerase beta. Biochemistry, 46, 2007
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4M6T
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![BU of 4m6t by Molmil](/molmil-images/mine/4m6t) | Structure of human Paf1 and Leo1 complex | Descriptor: | RNA polymerase II-associated factor 1 homolog, Linker, RNA polymerase-associated protein LEO1, ... | Authors: | Shen, Y, Qin, X. | Deposit date: | 2013-08-11 | Release date: | 2013-10-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.498 Å) | Cite: | Structural insights into Paf1 complex assembly and histone binding Nucleic Acids Res., 41, 2013
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2LU0
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![BU of 2lu0 by Molmil](/molmil-images/mine/2lu0) | NMR solution structure of the kappa-zeta region of S.cerevisiae group II intron ai5(gamma) | Descriptor: | RNA (49-MER) | Authors: | Donghi, D, Pechlaner, M, Finazzo, C, Knobloch, B, Sigel, R.K.O. | Deposit date: | 2012-06-05 | Release date: | 2013-04-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The structural stabilization of the kappa three-way junction by Mg(II) represents the first step in the folding of a group II intron. Nucleic Acids Res., 41, 2013
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4GXY
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![BU of 4gxy by Molmil](/molmil-images/mine/4gxy) | RNA structure | Descriptor: | Adenosylcobalamin, Adenosylcobalamin riboswitch, IRIDIUM HEXAMMINE ION, ... | Authors: | Serganov, A, Peselis, A. | Deposit date: | 2012-09-04 | Release date: | 2012-10-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural insights into ligand binding and gene expression control by an adenosylcobalamin riboswitch. Nat.Struct.Mol.Biol., 19, 2012
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2J92
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6ZBI
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![BU of 6zbi by Molmil](/molmil-images/mine/6zbi) | Ternary complex of Calmodulin bound to 2 molecules of NHE1 | Descriptor: | CALCIUM ION, Calmodulin-1, Sodium/hydrogen exchanger 1 | Authors: | Prestel, A, Kragelund, B.B, Pedersen, E.S, Pedersen, S.F, Sjoegaard-Frich, L.M. | Deposit date: | 2020-06-08 | Release date: | 2021-03-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Dynamic Na + /H + exchanger 1 (NHE1) - calmodulin complexes of varying stoichiometry and structure regulate Ca 2+ -dependent NHE1 activation. Elife, 10, 2021
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2HZS
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![BU of 2hzs by Molmil](/molmil-images/mine/2hzs) | Structure of the Mediator head submodule Med8C/18/20 | Descriptor: | RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20, RNA polymerase II mediator complex subunit 8 | Authors: | Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P. | Deposit date: | 2006-08-09 | Release date: | 2006-09-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20. Nat.Struct.Mol.Biol., 13, 2006
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2AHQ
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![BU of 2ahq by Molmil](/molmil-images/mine/2ahq) | |
1HES
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![BU of 1hes by Molmil](/molmil-images/mine/1hes) | |
4MZM
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![BU of 4mzm by Molmil](/molmil-images/mine/4mzm) | MazF from S. aureus crystal form I, P212121, 2.1 A | Descriptor: | mRNA interferase MazF | Authors: | Zorzini, V, Loris, R, van Nuland, N.A.J, Cheung, A. | Deposit date: | 2013-09-30 | Release date: | 2014-05-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and biophysical characterization of Staphylococcus aureus SaMazF shows conservation of functional dynamics. Nucleic Acids Res., 42, 2014
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2LI4
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![BU of 2li4 by Molmil](/molmil-images/mine/2li4) | |
7LNU
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![BU of 7lnu by Molmil](/molmil-images/mine/7lnu) | Ternary complex of the Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus bound to isopentenyl monophosphate and ATP | Descriptor: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Thomas, L.M, Singh, S, Scull, E.M, Bourne, C.R. | Deposit date: | 2021-02-08 | Release date: | 2021-12-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus . Acs Chem.Biol., 17, 2022
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7LNT
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![BU of 7lnt by Molmil](/molmil-images/mine/7lnt) | Ternary complex of the Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus bound to benzyl monophosphate and ATP | Descriptor: | (phenylmethyl) dihydrogen phosphate, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | Authors: | Thomas, L.M, Singh, S, Scull, E.M, Bourne, C.R. | Deposit date: | 2021-02-08 | Release date: | 2021-12-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus . Acs Chem.Biol., 17, 2022
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1Z58
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![BU of 1z58 by Molmil](/molmil-images/mine/1z58) | Crystal structure of a complex of the ribosome large subunit with rapamycin | Descriptor: | 23S RIBOSOMAL RNA, RAPAMYCIN IMMUNOSUPPRESSANT DRUG | Authors: | Amit, M, Berisio, R, Baram, D, Harms, J, Bashan, A, Yonath, A. | Deposit date: | 2005-03-17 | Release date: | 2005-06-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | A crevice adjoining the ribosome tunnel: Hints for cotranslational folding. Febs Lett., 579, 2005
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4R65
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![BU of 4r65 by Molmil](/molmil-images/mine/4r65) | Ternary complex crystal structure of R258A mutant of DNA polymerase Beta | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | Authors: | Batra, V.K, Beard, W.A, Wilson, S.H. | Deposit date: | 2014-08-22 | Release date: | 2014-10-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Substrate-induced DNA Polymerase beta Activation. J.Biol.Chem., 289, 2014
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5F7S
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![BU of 5f7s by Molmil](/molmil-images/mine/5f7s) | |
5CET
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![BU of 5cet by Molmil](/molmil-images/mine/5cet) | Crystal structure of Rv2837c | Descriptor: | Bifunctional oligoribonuclease and PAP phosphatase NrnA, MANGANESE (II) ION | Authors: | Wang, F, He, Q, Zhu, D, Liu, S, Gu, L. | Deposit date: | 2015-07-07 | Release date: | 2015-12-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Biochemical Insight into the Mechanism of Rv2837c from Mycobacterium tuberculosis as a c-di-NMP Phosphodiesterase J.Biol.Chem., 291, 2016
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4R66
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![BU of 4r66 by Molmil](/molmil-images/mine/4r66) | Ternary complex crystal structure of E295K mutant of DNA polymerase Beta | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | Authors: | Batra, V.K, Beard, W.A, Wilson, S.H. | Deposit date: | 2014-08-22 | Release date: | 2014-10-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Substrate-induced DNA Polymerase beta Activation. J.Biol.Chem., 289, 2014
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1B3O
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![BU of 1b3o by Molmil](/molmil-images/mine/1b3o) | TERNARY COMPLEX OF HUMAN TYPE-II INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP AND SELENAZOLE ADENINE DINUCLEOTIDE | Descriptor: | 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, PROTEIN (INOSINE MONOPHOSPHATE DEHYDROGENASE 2), ... | Authors: | Colby, T.D, Vanderveen, K, Strickler, M.D, Goldstein, B.M. | Deposit date: | 1998-12-14 | Release date: | 1999-04-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design. Proc.Natl.Acad.Sci.USA, 96, 1999
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7ROQ
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![BU of 7roq by Molmil](/molmil-images/mine/7roq) | Alternative Structure of Human ABCA1 | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Aller, S.G. | Deposit date: | 2021-08-01 | Release date: | 2022-01-19 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Refined ABCA1 with Domain-swapped Regulatory Domains Plos One, 2022
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4YGW
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![BU of 4ygw by Molmil](/molmil-images/mine/4ygw) | RNase S in complex with stabilized S peptide | Descriptor: | 1-hydroxypropan-2-one, Ribonuclease A C2, S-peptide: ACE-LYS-GLU-THR-ALA-ALA-HCS-LYS-PHE-GLU-HCS-GLN-HIS-MET-ASP-SER, ... | Authors: | Assem, N, Ferreira, D, Wolan, D.W, Dawson, P.E. | Deposit date: | 2015-02-26 | Release date: | 2015-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Acetone-Linked Peptides: A Convergent Approach for Peptide Macrocyclization and Labeling. Angew.Chem.Int.Ed.Engl., 54, 2015
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