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7WYV
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BU of 7wyv by Molmil
Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP in the presence of 40 mM Mg2+
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C.
Deposit date:2022-02-16
Release date:2022-04-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
7WYZ
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BU of 7wyz by Molmil
Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP with ouabain
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C.
Deposit date:2022-02-16
Release date:2022-04-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
7WZ0
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BU of 7wz0 by Molmil
Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by inorganic phosphate with ouabain
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C.
Deposit date:2022-02-16
Release date:2022-04-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
8GTT
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BU of 8gtt by Molmil
Cryo-EM structure of human Pannexin1 resembling Pannexin2 pore with W74R/R75Dmutations
Descriptor: Pannexin-1
Authors:Hussain, N, Penmatsa, A.
Deposit date:2022-09-08
Release date:2024-02-28
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms.
Nat Commun, 15, 2024
6WOU
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BU of 6wou by Molmil
Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 mutant R176Q in complex with FKBP12.6 in nanodisc
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
Authors:Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M.
Deposit date:2020-04-25
Release date:2020-08-05
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM.
Sci Adv, 6, 2020
8GTS
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BU of 8gts by Molmil
CryoEM structure of human Pannexin1 with R217H congenital mutation.
Descriptor: Pannexin-1
Authors:Hussain, N, Penmatsa, A.
Deposit date:2022-09-08
Release date:2024-02-28
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms.
Nat Commun, 15, 2024
4UIJ
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BU of 4uij by Molmil
Crystal structure of the BTB domain of KCTD13
Descriptor: BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 1, CHLORIDE ION
Authors:Pinkas, D.M, Sanvitale, C.E, Sorell, F.J, Solcan, N, Goubin, S, Canning, P, Williams, E, Chaikuad, A, Dixon Clarke, S.E, Tallant, C, Fonseca, M, Chalk, R, Doutch, J, Krojer, T, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.
Deposit date:2015-03-30
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases.
Biochem. J., 474, 2017
2VE3
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BU of 2ve3 by Molmil
Retinoic acid bound cyanobacterial CYP120A1
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 120, RETINOIC ACID
Authors:Kuhnel, K, Ke, N, Sligar, S.G, Schuler, M.A, Schlichting, I.
Deposit date:2007-10-15
Release date:2008-04-29
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of Substrate-Free and Retinoic Acid-Bound Cyanobacterial Cytochrome P450 Cyp120A1.
Biochemistry, 47, 2008
8GTR
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BU of 8gtr by Molmil
CryoEM structure of human Pannexin isoform 3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATIDYLETHANOLAMINE, Pannexin-3
Authors:Hussain, N, Penmatsa, A.
Deposit date:2022-09-08
Release date:2024-02-28
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms.
Nat Commun, 15, 2024
7NXD
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BU of 7nxd by Molmil
Cryo-EM structure of human integrin alpha5beta1 in the half-bent conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schumacher, S, Dedden, D, Vazquez Nunez, R, Matoba, K, Takagi, J, Biertumpfel, C, Mizuno, N.
Deposit date:2021-03-18
Release date:2021-08-25
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand.
Sci Adv, 7, 2021
5GHD
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BU of 5ghd by Molmil
SOLUTION STRUCTURE OF LYS39 ACETYLATED HUMAN SUMO1
Descriptor: Small ubiquitin-related modifier 1
Authors:Naik, M.T, Naik, N, Shih, H, Huang, T.
Deposit date:2016-06-19
Release date:2017-06-07
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structures of Human Sumo
To Be Published
1WM8
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BU of 1wm8 by Molmil
Solution Structure of BmP03 from the Venom of Scorpion Buthus martensii Karsch, 10 structures
Descriptor: Neurotoxin BmP03
Authors:Wu, H, He, F, Li, Y, Wu, G, Cao, C, Chen, X.
Deposit date:2004-07-05
Release date:2004-07-27
Last modified:2018-04-18
Method:SOLUTION NMR
Cite:Three-Dimensional Structure of BmP03 from Venom of Scorpion Buthus martensii Karsch
Acta Chim.Sinica, 58, 2000
3WGV
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BU of 3wgv by Molmil
Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state with oligomycin
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Kanai, R, Ogawa, H, Vilsen, B, Cornelius, F, Toyoshima, C.
Deposit date:2013-08-09
Release date:2013-10-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a Na1-bound Na1,K1-ATPase preceding the E1P state
Nature, 502, 2013
5DAH
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BU of 5dah by Molmil
Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide
Descriptor: Histone H3 peptide, Protein AF-10, SULFATE ION, ...
Authors:Chen, S, Patel, D.J.
Deposit date:2015-08-19
Release date:2015-10-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.611 Å)
Cite:The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol.Cell, 60, 2015
7VUO
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BU of 7vuo by Molmil
Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
Descriptor: CALCIUM ION, Calmodulin-1, Kv7.1
Authors:Chen, L.
Deposit date:2021-11-03
Release date:2022-11-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.679 Å)
Cite:Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
To Be Published
5CFB
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BU of 5cfb by Molmil
Crystal Structure of Human Glycine Receptor alpha-3 Bound to Strychnine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alpha-3,Glycine receptor subunit alpha-3, ...
Authors:Shaffer, P.L, Huang, X, Chen, H.
Deposit date:2015-07-08
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Crystal structure of human glycine receptor-alpha 3 bound to antagonist strychnine.
Nature, 526, 2015
2K7M
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BU of 2k7m by Molmil
Structure of the Connexin40 Carboxyl terminal Domain
Descriptor: Gap junction alpha-5 protein
Authors:Bouvier, D, Spagnol, G, Kieken, F, Vitrac, H, Kellezi, A, Forge, V.
Deposit date:2008-08-14
Release date:2009-07-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Characterization of the structure and intermolecular interactions between the connexin40 and connexin43 carboxyl-terminal and cytoplasmic loop domains.
J.Biol.Chem., 284, 2009
6PX7
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BU of 6px7 by Molmil
Dg12a in Weaponisation 'on the fly': Convergent recruitment of knottin and defensin scaffolds as neurotoxins in the venom of assassin fly Dolopus genitalis (Diptera: Asilidae)
Descriptor: Venom polypeptide
Authors:Agwa, A.J, Schroeder, C.
Deposit date:2019-07-25
Release date:2020-01-22
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Weaponisation 'on the fly': Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies.
Insect Biochem.Mol.Biol., 118, 2019
6PX8
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BU of 6px8 by Molmil
Dg3b in Weaponisation 'on the fly': Convergent recruitment of knottin and defensin scaffolds as neurotoxins in the venom of assassin fly Dolopus genitalis (Diptera: Asilidae)
Descriptor: Venom polypeptide
Authors:Agwa, A.J, Schroeder, C.
Deposit date:2019-07-25
Release date:2020-01-22
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Weaponisation 'on the fly': Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies.
Insect Biochem.Mol.Biol., 118, 2019
2JP3
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BU of 2jp3 by Molmil
Solution Structure of the human FXYD4 (CHIF) protein in SDS micelles
Descriptor: FXYD domain-containing ion transport regulator 4
Authors:Franzin, C.M, Teriete, P, Marassi, F.M.
Deposit date:2007-04-18
Release date:2008-03-04
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Structural similarity of a membrane protein in micelles and membranes
J.Am.Chem.Soc., 129, 2007
6SGB
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BU of 6sgb by Molmil
mt-SSU assemblosome of Trypanosoma brucei
Descriptor: 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2019-08-03
Release date:2019-09-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Science, 365, 2019
2JUL
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BU of 2jul by Molmil
NMR Structure of DREAM
Descriptor: CALCIUM ION, Calsenilin
Authors:Ames, J.
Deposit date:2007-08-30
Release date:2008-04-22
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR structure of DREAM: Implications for Ca(2+)-dependent DNA binding and protein dimerization.
Biochemistry, 47, 2008
5B7A
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BU of 5b7a by Molmil
SOLUTION STRUCTURE OF LYS37 ACETYLATED HUMAN SUMO1
Descriptor: Small ubiquitin-related modifier 1
Authors:Naik, M.T, Naik, N, Shih, H, Huang, T.
Deposit date:2016-06-05
Release date:2017-06-07
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structures Of Human Sumo
To Be Published
2YGG
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BU of 2ygg by Molmil
Complex of CaMBR and CaM
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ...
Authors:Koester, S, Yildiz, O.
Deposit date:2011-04-15
Release date:2011-09-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.227 Å)
Cite:Structure of Human Na+/H+ Exchanger Nhe1 Regulatory Region in Complex with Cam and Ca2+
J.Biol.Chem., 286, 2011
7T64
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BU of 7t64 by Molmil
Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the closed state
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION
Authors:Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
Deposit date:2021-12-13
Release date:2022-07-20
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022

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数据于2024-07-24公开中

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