PDB: 533 resultsInfo pagesStatus searchChemie searchBIRD

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4J9G	Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 at pH7 Descriptor: GLYCEROL, P7, SULFATE ION, ... Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 To be Published
4JJD	Crystal structure of the N114A Abl-SH3 domain mutant at pH4 Descriptor: DI(HYDROXYETHYL)ETHER, SODIUM ION, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A, Martin-Garcia, J.M. Deposit date: 2013-03-07 Release date: 2014-03-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of the Abl-SH3 domain at pH5 To be Published
1A0N	NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE COMPLEXED WITH THE SYNTHETIC PEPTIDE P2L CORRESPONDING TO RESIDUES 91-104 OF THE P85 SUBUNIT OF PI3-KINASE, FAMILY OF 25 STRUCTURES Descriptor: FYN, PRO-PRO-ARG-PRO-LEU-PRO-VAL-ALA-PRO-GLY-SER-SER-LYS-THR Authors: Renzoni, D.A, Pugh, D.J.R, Siligardi, G, Das, P, Morton, C.J, Rossi, C, Waterfield, M.D, Campbell, I.D, Ladbury, J.E. Deposit date: 1997-12-05 Release date: 1998-02-25 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase. Biochemistry, 35, 1996
1AWJ	INTRAMOLECULAR ITK-PROLINE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: ITK Authors: Andreotti, A.H, Bunnell, S.C, Feng, S, Berg, L.J, Schreiber, S.L. Deposit date: 1997-10-02 Release date: 1998-01-14 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Regulatory intramolecular association in a tyrosine kinase of the Tec family. Nature, 385, 1997
1AZG	NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE KINASE COMPLEXED WITH THE SYNTHETIC PEPTIDE P2L CORRESPONDING TO RESIDUES 91-104 OF THE P85 SUBUNIT OF PI3-KINASE, MINIMIZED AVERAGE (PROBMAP) STRUCTURE Descriptor: FYN, PRO-PRO-ARG-PRO-LEU-PRO-VAL-ALA-PRO-GLY-SER-SER-LYS-THR Authors: Renzoni, D.A, Pugh, D.J.R, Siligardi, G, Das, P, Morton, C.J, Rossi, C, Waterfield, M.D, Campbell, I.D, Ladbury, J.E. Deposit date: 1997-11-18 Release date: 1998-02-25 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase. Biochemistry, 35, 1996
1AWW	SH3 DOMAIN FROM BRUTON'S TYROSINE KINASE, NMR, 42 STRUCTURES Descriptor: BRUTON'S TYROSINE KINASE Authors: Hansson, H, Mattsson, P.T, Allard, P, Haapaniemi, P, Vihinen, M, Smith, C.I.E, Hard, T. Deposit date: 1997-10-06 Release date: 1998-04-08 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution structure of the SH3 domain from Bruton's tyrosine kinase. Biochemistry, 37, 1998
1AOJ	THE SH3 DOMAIN OF EPS8 EXISTS AS A NOVEL INTERTWINED DIMER Descriptor: EPS8 Authors: Kishan, K.V.R, Newcomer, M.E. Deposit date: 1997-07-07 Release date: 1998-07-08 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The SH3 domain of Eps8 exists as a novel intertwined dimer. Nat.Struct.Biol., 4, 1997
1BU1	SRC FAMILY KINASE HCK SH3 DOMAIN Descriptor: PROTEIN (HEMOPOIETIC CELL KINASE) Authors: Arold, S, Franken, P, Dumas, C. Deposit date: 1998-09-09 Release date: 1998-11-11 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.6 Å) Cite: RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef. Biochemistry, 37, 1998
1B07	CRK SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR Descriptor: PHENYLETHANE, PROTEIN (PROTO-ONCOGENE CRK (CRK)), PROTEIN (SH3 PEPTOID INHIBITOR) Authors: Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. Deposit date: 1998-11-17 Release date: 1999-01-06 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science, 282, 1998
1AWO	THE SOLUTION NMR STRUCTURE OF ABL SH3 AND ITS RELATIONSHIP TO SH2 IN THE SH(32) CONSTRUCT, 20 STRUCTURES Descriptor: ABL TYROSINE KINASE Authors: Cowburn, D. Deposit date: 1997-10-03 Release date: 1998-01-28 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: The solution structure of Abl SH3, and its relationship to SH2 in the SH(32) construct. Structure, 3, 1995
1BBZ	CRYSTAL STRUCTURE OF THE ABL-SH3 DOMAIN COMPLEXED WITH A DESIGNED HIGH-AFFINITY PEPTIDE LIGAND: IMPLICATIONS FOR SH3-LIGAND INTERACTIONS Descriptor: ABL TYROSINE KINASE, PEPTIDE P41, SULFATE ION Authors: Pisabarro, M.T, Serrano, L, Wilmanns, M. Deposit date: 1998-04-28 Release date: 1998-11-25 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of the abl-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions. J.Mol.Biol., 281, 1998
1AEY	ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, SOLUTION NMR, 15 STRUCTURES Descriptor: ALPHA-SPECTRIN Authors: Blanco, F.J, Ortiz, A.R, Serrano, L. Deposit date: 1997-03-02 Release date: 1997-05-15 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: 1H and 15N NMR assignment and solution structure of the SH3 domain of spectrin: comparison of unrefined and refined structure sets with the crystal structure. J.Biomol.NMR, 9, 1997
1ABO	CRYSTAL STRUCTURE OF THE COMPLEX OF THE ABL TYROSINE KINASE SH3 DOMAIN WITH 3BP-1 SYNTHETIC PEPTIDE Descriptor: 3BP-1 SYNTHETIC PEPTIDE, 10 RESIDUES, ABL TYROSINE KINASE, ... Authors: Musacchio, A, Wilmanns, M, Saraste, M. Deposit date: 1995-05-19 Release date: 1995-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nat.Struct.Biol., 1, 1994
1BK2	A-SPECTRIN SH3 DOMAIN D48G MUTANT Descriptor: A-SPECTRIN Authors: Martinez, J.C, Pisabarro, M.T, Serrano, L. Deposit date: 1998-07-14 Release date: 1999-02-16 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Obligatory steps in protein folding and the conformational diversity of the transition state. Nat.Struct.Biol., 5, 1998
1ABQ	CRYSTAL STRUCTURE OF THE UNLIGANDED ABL TYROSINE KINASE SH3 DOMAIN Descriptor: ABL TYROSINE KINASE SRC-HOMOLOGY 3 (SH3) DOMAIN Authors: Musacchio, A, Wilmanns, M, Saraste, M. Deposit date: 1995-05-19 Release date: 1995-10-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.8 Å) Cite: High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nat.Struct.Biol., 1, 1994
1AZE	NMR STRUCTURE OF THE COMPLEX BETWEEN THE C32S-Y7V MUTANT OF THE NSH3 DOMAIN OF GRB2 WITH A PEPTIDE FROM SOS, 10 STRUCTURES Descriptor: GRB2, SOS Authors: Vidal, M, Gincel, E, Goudreau, N, Cornille, F, Parker, F, Duchesne, M, Tocque, B, Garbay, C, Roques, B.P. Deposit date: 1997-11-17 Release date: 1999-05-18 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin. J.Mol.Biol., 290, 1999
1AWX	SH3 DOMAIN FROM BRUTON'S TYROSINE KINASE, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: BRUTON'S TYROSINE KINASE Authors: Hansson, H, Mattsson, P.T, Allard, P, Haapaniemi, P, Vihinen, M, Smith, C.I.E, Hard, T. Deposit date: 1997-10-06 Release date: 1998-04-08 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution structure of the SH3 domain from Bruton's tyrosine kinase. Biochemistry, 37, 1998
1CSK	THE CRYSTAL STRUCTURE OF HUMAN CSKSH3: STRUCTURAL DIVERSITY NEAR THE RT-SRC AND N-SRC LOOP Descriptor: C-SRC SH3 DOMAIN Authors: Mathieu, M, Wierenga, R.K. Deposit date: 1994-03-22 Release date: 1994-07-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The crystal structure of human CskSH3: structural diversity near the RT-Src and n-Src loop. FEBS Lett., 341, 1994
2RNA	Itk SH3 average minimized Descriptor: Tyrosine-protein kinase ITK/TSK Authors: Severin, A.J. Deposit date: 2007-12-08 Release date: 2007-12-25 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: NMR structure note: murine Itk SH3 domain To be Published
2RQV	Solution structure of SH3CI domain of Bem1p Descriptor: Bud emergence protein 1 Authors: Takaku, T, Ogura, K, Inagaki, F. Deposit date: 2009-12-21 Release date: 2010-04-21 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42 J.Biol.Chem., 285, 2010
2RMO	Solution structure of alpha-spectrin_SH3-bergerac from Chicken Descriptor: Spectrin alpha chain, brain Authors: Kutyshenko, V.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Fedyukina, D.V, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V. Deposit date: 2007-11-07 Release date: 2008-09-30 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Study of the structure and dynamics of a chimeric variant of the SH3 domain (SHA-Bergerac) by NMR spectroscopy Russ.J.Bioorganic Chem., 34, 2008
2RQW	Solution structure of Bem1p SH3CI domain complexed with Ste20p-PRR peptide Descriptor: 24-meric peptide from Serine/threonine-protein kinase STE20, Bud emergence protein 1 Authors: Takaku, T, Ogura, K, Inagaki, F. Deposit date: 2009-12-21 Release date: 2010-04-21 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42 J.Biol.Chem., 285, 2010
2ROT	Structure of chimeric variant of SH3 domain- SHH Descriptor: Spectrin alpha chain, brain Authors: Kutyshenko, N.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V. Deposit date: 2008-04-10 Release date: 2009-04-28 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Solution structure and dynamics of the chimeric SH3 domains, SHH- and SHA-"Bergeracs". Biochim.Biophys.Acta, 1794, 2009
2RPN	A crucial role for high intrinsic specificity in the function of yeast SH3 domains Descriptor: Actin-binding protein, Actin-regulating kinase 1 Authors: Stollar, E.J, Garcia, B, Chong, A, Forman-Kay, J, Davidson, A. Deposit date: 2008-06-12 Release date: 2009-06-16 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p J.Biol.Chem., 284, 2009
5NP2	Abl1 SH3 pTyr89/134 Descriptor: Tyrosine-protein kinase ABL1 Authors: Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. Deposit date: 2017-04-13 Release date: 2018-05-16 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019

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