5NP2

Abl1 SH3 pTyr89/134

Summary for 5NP2

Entry DOI	10.2210/pdb5np2/pdb
Descriptor	Tyrosine-protein kinase ABL1 (2 entities in total)
Functional Keywords	signaling, tyrosine phosphorylation, sh3 domain, kinase, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	13818.86
Authors	Mero, B.,Radnai, L.,Gogl, G.,Leveles, I.,Buday, L. (deposition date: 2017-04-13, release date: 2018-05-16, Last modification date: 2024-01-17)
Primary citation	Mero, B.,Radnai, L.,Gogl, G.,Toke, O.,Leveles, I.,Koprivanacz, K.,Szeder, B.,Dulk, M.,Kudlik, G.,Vas, V.,Cserkaszky, A.,Sipeki, S.,Nyitray, L.,Vertessy, B.G.,Buday, L. Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294:4608-4620, 2019 Cited by PubMed: 30659095 DOI: 10.1074/jbc.RA118.004732 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation