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3O2K
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BU of 3o2k by Molmil
Crystal Structure of Brevianamide F Prenyltransferase Complexed with Brevianamide F and Dimethylallyl S-thiolodiphosphate
Descriptor: (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Brevianamide F prenyltransferase, ...
Authors:Jost, M, Zocher, G.E, Stehle, T.
Deposit date:2010-07-22
Release date:2010-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-function analysis of an enzymatic prenyl transfer reaction identifies a reaction chamber with modifiable specificity.
J.Am.Chem.Soc., 132, 2010
3KMZ
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BU of 3kmz by Molmil
Crystal structure of RARalpha ligand binding domain in complex with the inverse agonist BMS493 and a corepressor fragment
Descriptor: 4-{(E)-2-[5,5-dimethyl-8-(phenylethynyl)-5,6-dihydronaphthalen-2-yl]ethenyl}benzoic acid, GLYCEROL, Nuclear receptor corepressor 1, ...
Authors:Bourguet, W, le Maire, A.
Deposit date:2009-11-11
Release date:2010-06-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor.
Nat.Struct.Mol.Biol., 17, 2010
3AQT
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BU of 3aqt by Molmil
CRYSTAL STRUCTURE OF RolR (NCGL1110) complex WITH ligand RESORCINOL
Descriptor: Bacterial regulatory proteins, tetR family, RESORCINOL
Authors:Li, D.F, Zhang, N, Hou, Y.J, Liu, S.J, Wang, D.C.
Deposit date:2010-11-18
Release date:2011-07-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of the transcriptional repressor RolR reveals a novel recognition mechanism between inducer and regulator.
Plos One, 6, 2011
4E4D
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BU of 4e4d by Molmil
Crystal structure of mouse RANKL-OPG complex
Descriptor: CHLORIDE ION, Tumor necrosis factor ligand superfamily member 11, soluble form, ...
Authors:Nelson, C.A, Fremont, D.H.
Deposit date:2012-03-12
Release date:2012-10-24
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor.
Structure, 20, 2012
4AWM
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BU of 4awm by Molmil
Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with (-)-epigallocatechin gallate from green tea
Descriptor: (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, MANGANESE (II) ION, POLYMERASE PA
Authors:Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S.
Deposit date:2012-06-04
Release date:2012-08-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
Plos Pathog., 8, 2012
1EXT
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BU of 1ext by Molmil
EXTRACELLULAR DOMAIN OF THE 55KDA TUMOR NECROSIS FACTOR RECEPTOR. CRYSTALLIZED AT PH3.7 IN P 21 21 21.
Descriptor: MAGNESIUM ION, SULFATE ION, TUMOR NECROSIS FACTOR RECEPTOR
Authors:Naismith, J.H, Sprang, S.R.
Deposit date:1996-07-03
Release date:1997-01-11
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of the extracellular domain of the type I tumor necrosis factor receptor.
Structure, 4, 1996
3TZS
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BU of 3tzs by Molmil
Crystal structure of Neutrophil gelatinase-associated lipocalin NGAL (C87S mutant) in complex with fragment 1026, phenylurea
Descriptor: 1,2-ETHANEDIOL, 1-phenylurea, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-09-27
Release date:2011-10-12
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Parsing the functional specificity of Siderocalin / Lipocalin 2 / NGAL for siderophores and related small-molecule ligands
To be published, 7
2M9P
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BU of 2m9p by Molmil
NMR structure of an inhibitor bound dengue NS3 protease
Descriptor: Serine protease inhibitor, Serine protease subunit NS2B, Serine protease NS3
Authors:Gibbs, A, Tounge, B, Steele, R.
Deposit date:2013-06-18
Release date:2014-07-09
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:NMR structure of an inhibitor bound dengue NS3 protease provides new insights into the NS2B NS3 ligand interactions
To be Published
4K72
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BU of 4k72 by Molmil
CFTR Associated Ligand (CAL) PDZ domain bound to peptide iCAL36-VQD (ANSRVQDSII)
Descriptor: Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36-VQD peptide
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2013-04-16
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Structure, 22, 2014
4K78
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BU of 4k78 by Molmil
CFTR Associated Ligand (CAL) E317A PDZ domain bound to peptide iCAL36-QDTRL (ANSRWQDTRL)
Descriptor: Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36-QDTRL peptide
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2013-04-16
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Structure, 22, 2014
3HFT
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BU of 3hft by Molmil
Crystal structure of a putative polysaccharide deacetylase involved in o-antigen biosynthesis (wbms, bb0128) from bordetella bronchiseptica at 1.90 A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, UNKNOWN LIGAND, ...
Authors:Joint Center for Structural Genomics, Joint Center for Structural Genomics (JCSG)
Deposit date:2009-05-12
Release date:2009-06-23
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of WbmS, polysaccharide deacetylase involved in O-antigen biosynthesis (NP_886680.1) from BORDETELLA BRONCHISEPTICA at 1.90 A resolution
To be published
4K75
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BU of 4k75 by Molmil
CFTR Associated Ligand (CAL) PDZ domain bound to peptide iCAL36-QDTRL (ANSRWQDTRL)
Descriptor: Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36-QDTRL peptide
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2013-04-16
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Structure, 22, 2014
5HZW
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BU of 5hzw by Molmil
Crystal structure of the orphan region of human endoglin/CD105 in complex with BMP9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Growth/differentiation factor 2, Maltose-binding periplasmic protein,Endoglin, ...
Authors:Bokhove, M, Saito, T, Jovine, L.
Deposit date:2016-02-03
Release date:2017-06-07
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (4.451 Å)
Cite:Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.
Cell Rep, 19, 2017
7BWO
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BU of 7bwo by Molmil
Consensus chitin binding protein
Descriptor: Chitin binding beak protein 3
Authors:Mohanram, H, Miserez, A.
Deposit date:2020-04-15
Release date:2021-04-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of a consensus chitin-binding domain revealed by solution NMR.
J.Struct.Biol., 213, 2021
7BWE
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BU of 7bwe by Molmil
Consensus Chitin binding domain
Descriptor: Chitin binding beak protein 3
Authors:Mohanram, H, Miserez, A.
Deposit date:2020-04-14
Release date:2021-04-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of a consensus chitin-binding domain revealed by solution NMR.
J.Struct.Biol., 213, 2021
6NM1
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BU of 6nm1 by Molmil
The crystal structure of the Staphylococcus aureus Fatty acid Kinase (Fak) B1 protein A158L mutant to 2.33 Angstrom resolution exhibits a conformation change compared to the wild type form
Descriptor: Fatty acid Kinase (Fak) B1 protein, MYRISTIC ACID
Authors:Cuypers, M.G, Gullett, J.M, Subramanian, C, Ericson, M, White, S.W, Rock, C.O.
Deposit date:2019-01-10
Release date:2020-01-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Identification of structural transitions in bacterial fatty acid binding proteins that permit ligand entry and exit at membranes.
J.Biol.Chem., 298, 2022
2M9Q
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BU of 2m9q by Molmil
NMR structure of an inhibitor bound dengue NS3 protease
Descriptor: Serine protease inhibitor, Serine protease subunit NS2B, Serine protease NS3
Authors:Gibbs, A, Steele, R, Tounge, B.
Deposit date:2013-06-18
Release date:2014-07-09
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:NMR structure of an inhibitor bound dengue NS3 protease provides new insights into the NS2B NS3 ligand interactions
To be Published
3VRF
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BU of 3vrf by Molmil
The crystal structure of hemoglobin from woolly mammoth in the carbonmonoxy forms
Descriptor: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, ...
Authors:Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H.
Deposit date:2012-04-09
Release date:2012-11-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012
1A15
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BU of 1a15 by Molmil
SDF-1ALPHA
Descriptor: STROMAL DERIVED FACTOR-1ALPHA, SULFATE ION
Authors:Dealwis, C.G, Fernandez, E.J, Lolis, E.
Deposit date:1997-12-22
Release date:1998-08-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of chemically synthesized [N33A] stromal cell-derived factor 1alpha, a potent ligand for the HIV-1 "fusin" coreceptor.
Proc.Natl.Acad.Sci.USA, 95, 1998
4Q6H
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BU of 4q6h by Molmil
CFTR Associated Ligand (CAL) bound to last 6 residues of CFTR (decameric peptide: iCAL36VQDTRL)
Descriptor: CFTR-associated ligand, SULFITE ION, iCAL36-VQDTRL peptide
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2014-04-22
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Understanding PDZ Affinity and Selectivity: All Residues Considered
TO BE PUBLISHED
5NZ1
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BU of 5nz1 by Molmil
Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with sutezolid
Descriptor: HTH-type transcriptional regulator EthR, ~{N}-[[(5~{S})-3-(3-fluoranyl-4-thiomorpholin-4-yl-phenyl)-2-oxidanylidene-1,3-oxazolidin-5-yl]methyl]ethanamide
Authors:Mendes, V, Blaszczyk, M, Nikiforov, P.O, Blundell, T.L.
Deposit date:2017-05-12
Release date:2018-05-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:The antibiotics linezolid and sutezolid are ligands for Mycobacterium tuberculosis EthR
To Be Published
4E0U
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BU of 4e0u by Molmil
Crystal structure of CdpNPT in complex with thiolodiphosphate and (S)-benzodiazependione
Descriptor: (3S)-3-(1H-indol-3-ylmethyl)-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione, 1,2-ETHANEDIOL, Cyclic dipeptide N-prenyltransferase, ...
Authors:Schuller, J.M, Zocher, G, Stehle, T.
Deposit date:2012-03-05
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and catalytic mechanism of a cyclic dipeptide prenyltransferase with broad substrate promiscuity.
J.Mol.Biol., 422, 2012
3IEH
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BU of 3ieh by Molmil
Crystal structure of Putative metallopeptidase (YP_001051774.1) from SHEWANELLA BALTICA OS155 at 2.45 A resolution
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Putative metallopeptidase, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2009-07-22
Release date:2009-08-04
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of Putative metallopeptidase (YP_001051774.1) from SHEWANELLA BALTICA OS155 at 2.45 A resolution
To be published
4E0T
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BU of 4e0t by Molmil
Crystal structure of CdpNPT in its unbound state
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Cyclic dipeptide N-prenyltransferase, ...
Authors:Schuller, J.M, Zocher, G, Stehle, T.
Deposit date:2012-03-05
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure and catalytic mechanism of a cyclic dipeptide prenyltransferase with broad substrate promiscuity.
J.Mol.Biol., 422, 2012
3OJV
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BU of 3ojv by Molmil
Crystal Structure of FGF1 complexed with the ectodomain of FGFR1c exhibiting an ordered ligand specificity-determining betaC'-betaE loop
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Basic fibroblast growth factor receptor 1, Heparin-binding growth factor 1
Authors:Beenken, A, Mohammadi, M.
Deposit date:2010-08-23
Release date:2011-12-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1.
J.Biol.Chem., 287, 2012

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数据于2024-11-13公开中

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