5NZ1

Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with sutezolid

Summary for 5NZ1

• Entry DOI: 10.2210/pdb5nz1/pdb
• Descriptor: HTH-type transcriptional regulator EthR, ~{N}-[[(5~{S})-3-(3-fluoranyl-4-thiomorpholin-4-yl-phenyl)-2-oxidanylidene-1,3-oxazolidin-5-yl]methyl]ethanamide (3 entities in total)
• Functional Keywords: ethr, transcription, represor, boosting effect
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 8
• Total formula weight: 203134.27

Authors

Mendes, V.,Blaszczyk, M.,Nikiforov, P.O.,Blundell, T.L. (deposition date: 2017-05-12, release date: 2018-05-30, Last modification date: 2024-01-17)

• Primary citation: Nikiforov, P.O.,Blaszczyk, M.,Mendes, V.,Boshoff, H.I.,Barry, C.E.,Blundell, T.L.,Abell, C.; The antibiotics linezolid and sutezolid are ligands for Mycobacterium tuberculosis EthR; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.33 Å)