5NZ1
Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with sutezolid
Summary for 5NZ1
Entry DOI | 10.2210/pdb5nz1/pdb |
Descriptor | HTH-type transcriptional regulator EthR, ~{N}-[[(5~{S})-3-(3-fluoranyl-4-thiomorpholin-4-yl-phenyl)-2-oxidanylidene-1,3-oxazolidin-5-yl]methyl]ethanamide (3 entities in total) |
Functional Keywords | ethr, transcription, represor, boosting effect |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 8 |
Total formula weight | 203134.27 |
Authors | Mendes, V.,Blaszczyk, M.,Nikiforov, P.O.,Blundell, T.L. (deposition date: 2017-05-12, release date: 2018-05-30, Last modification date: 2024-01-17) |
Primary citation | Nikiforov, P.O.,Blaszczyk, M.,Mendes, V.,Boshoff, H.I.,Barry, C.E.,Blundell, T.L.,Abell, C. The antibiotics linezolid and sutezolid are ligands for Mycobacterium tuberculosis EthR To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
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