5NZ1

Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with sutezolid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	HTH-type transcriptional regulator EthR	polymer	228	25259.3	8	UniProt (P9WMC1) Pfam (PF00440) Pfam (PF21313)	Mycobacterium tuberculosis
2	I, J, K (A, C, D)	~{N}-[[(5~{S})-3-(3-fluoranyl-4-thiomorpholin-4-yl-phenyl)-2-oxidanylidene-1,3-oxazolidin-5-yl]methyl]ethanamide	non-polymer		353.4	3	Chemie (9EN)
3	L, M, N, O, P... (A, B, C, D, E...)	water	water		18.0	225	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 2 - 216 (UniProt: P9WMC1)

PDB	External Database	Details
Met -3	-	initiating methionine
Asp -2	-	expression tag
Ile -1	-	expression tag
Glu 0	-	expression tag
Phe 1	-	expression tag
Gly 217	-	expression tag
Ser 218	-	expression tag
His 219	-	expression tag
His 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag
His 224	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	202074.0
Non-Polymers*	Number of molecules	3
	Total formula weight	1060.2
All*	Total formula weight	203134.3

*Water molecules are not included.