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2J1W
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BU of 2j1w by Molmil
Human p53 core domain mutant M133L-V143A-V203A-N239Y-N268D
Descriptor: CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Joerger, A.C, Fersht, A.R.
Deposit date:2006-08-15
Release date:2006-09-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs.
Proc.Natl.Acad.Sci.USA, 103, 2006
2PE5
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BU of 2pe5 by Molmil
Crystal Structure of the Lac Repressor bound to ONPG in repressed state
Descriptor: 2-nitrophenyl beta-D-galactopyranoside, DNA (5'-D(*DAP*DAP*DTP*DTP*DGP*DTP*DGP*DAP*DGP*DCP*DGP*DCP*DTP*DCP*DAP*DCP*DAP*DAP*DTP*DT)-3'), Lactose operon repressor
Authors:Daber, R, Stayrook, S.E, Rosenberg, A, Lewis, M.
Deposit date:2007-04-02
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural analysis of lac repressor bound to allosteric effectors
J.Mol.Biol., 370, 2007
3O3K
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BU of 3o3k by Molmil
Crystal structure of AF1382 from Archaeoglobus fulgidus
Descriptor: Uncharacterized protein AF_1382
Authors:Zhu, J.-Y, Zhao, M, Fu, Z.-Q, Yang, H, Chang, J, Xu, H, Chen, L, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2010-07-24
Release date:2010-08-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Archaeoglobus fulgidus orphan ORF AF1382 determined by sulfur SAD from a moderately diffracting crystal.
Acta Crystallogr.,Sect.D, 68, 2012
4LFU
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BU of 4lfu by Molmil
Crystal structure of Escherichia coli SdiA in the space group C2
Descriptor: CHLORIDE ION, Regulatory protein SdiA, TETRAETHYLENE GLYCOL
Authors:Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K.
Deposit date:2013-06-27
Release date:2014-03-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
Acta Crystallogr.,Sect.D, 70, 2014
4LGW
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BU of 4lgw by Molmil
Crystal structure of Escherichia coli SdiA in the space group P6522
Descriptor: GLYCEROL, Regulatory protein SdiA
Authors:Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K.
Deposit date:2013-06-28
Release date:2014-03-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
Acta Crystallogr.,Sect.D, 70, 2014
1M0I
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BU of 1m0i by Molmil
Crystal Structure of Bacteriophage T7 Endonuclease I with a Wild-Type Active Site
Descriptor: SULFATE ION, endodeoxyribonuclease I
Authors:Hadden, J.M, Declais, A.C, Phillips, S.E, Lilley, D.M.
Deposit date:2002-06-13
Release date:2002-12-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Metal ions bound at the active site of the junction-resolving enzyme T7 endonuclease I
Embo J., 21, 2002
5LY0
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BU of 5ly0 by Molmil
Crystal structure of LOB domain of Ramosa2 from Wheat
Descriptor: LOB family transfactor Ramosa2.1, ZINC ION
Authors:Wei, X.-B, Zhang, B, Chen, W.-F, Fan, S.-H, Rety, S, Xi, X.-G.
Deposit date:2016-09-23
Release date:2017-10-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.877 Å)
Cite:Structural analysis reveals a "molecular calipers" mechanism for a LATERAL ORGAN BOUNDARIES DOMAIN transcription factor protein from wheat.
J. Biol. Chem., 294, 2019
5MBV
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BU of 5mbv by Molmil
Cryo-EM structure of Lambda Phage protein GamS bound to RecBCD.
Descriptor: Host-nuclease inhibitor protein gam, RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ...
Authors:Wilkinson, M, Chaban, Y, Wigley, D.B.
Deposit date:2016-11-08
Release date:2017-01-11
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones.
Elife, 5, 2016
5LJ4
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BU of 5lj4 by Molmil
Crystal structure of DNA duplex containing ZP base pair
Descriptor: CALCIUM ION, ODN2
Authors:Agnew, C.R.J, Brady, R.L.
Deposit date:2016-07-17
Release date:2017-05-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural Basis of the Mispairing of an Artificially Expanded Genetic Information System
Chem, 1, 2016
1M0D
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BU of 1m0d by Molmil
Crystal Structure of Bacteriophage T7 Endonuclease I with a Wild-Type Active Site and Bound Manganese Ions
Descriptor: Endodeoxyribonuclease I, MANGANESE (II) ION, SULFATE ION
Authors:Hadden, J.M, Declais, A.C, Phillips, S.E, Lilley, D.M.
Deposit date:2002-06-12
Release date:2002-07-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Metal ions bound at the active site of the junction-resolving enzyme T7 endonuclease I.
EMBO J., 21, 2002
4TV7
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BU of 4tv7 by Molmil
Crystal structure of Bacillus subtilis GabR at 2.05 Angstroms resolution
Descriptor: HTH-type transcriptional regulatory protein GabR
Authors:Goto, M, Okuda, K, Yoshimura, T.
Deposit date:2014-06-26
Release date:2014-12-24
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Role of the aminotransferase domain in Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator
Mol. Microbiol., 95, 2015
5LRR
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BU of 5lrr by Molmil
The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione
Descriptor: GLUTATHIONE, HYDROGENPHOSPHATE ION, Listeriolysin positive regulatory factor A, ...
Authors:Hall, M, Grundstrom, C, Begum, A, Lindberg, M, Sauer, U.H, Almqvist, F, Johansson, J, Sauer-Eriksson, A.E.
Deposit date:2016-08-19
Release date:2016-12-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.171 Å)
Cite:Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
4F8D
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BU of 4f8d by Molmil
Crystal Structure of an R46A mutant of the Restriction-Modification Controller Protein C.Esp1396I (Monoclinic Form)
Descriptor: Regulatory protein, SODIUM ION, SULFATE ION
Authors:Martin, R.N.A, McGeehan, J.E, Kneale, G.G.
Deposit date:2012-05-17
Release date:2013-04-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I.
Plos One, 9, 2014
4K2E
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BU of 4k2e by Molmil
HlyU from Vibrio cholerae N16961
Descriptor: Transcriptional activator HlyU
Authors:Mukherjee, D, Datta, A.B, Chakrabarti, P.
Deposit date:2013-04-09
Release date:2014-04-30
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of HlyU, the hemolysin gene transcription activator, from Vibrio cholerae N16961 and functional implications.
Biochim.Biophys.Acta, 1844, 2014
3D1N
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BU of 3d1n by Molmil
Structure of human Brn-5 transcription factor in complex with corticotrophin-releasing hormone gene promoter
Descriptor: 5'-D(*DAP*DGP*DCP*DAP*DTP*DAP*DAP*DAP*DTP*DAP*DAP*DTP*DAP*DA)-3', 5'-D(*DTP*DTP*DAP*DTP*DTP*DAP*DTP*DTP*DTP*DAP*DTP*DGP*DCP*DT)-3', POU domain, ...
Authors:Pereira, J.H, Ha, S.C, Kim, S.-H.
Deposit date:2008-05-06
Release date:2009-05-26
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of human Brn-5 transcription factor in complex with CRH gene promoter.
J.Struct.Biol., 167, 2009
4FBI
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BU of 4fbi by Molmil
Crystal Structure of an R46A mutant of the Restriction-Modification Controller Protein C.Esp1396I (Trigonal Form)
Descriptor: GLYCEROL, Regulatory protein
Authors:Martin, R.N.A, McGeehan, J.E, Kneale, G.G.
Deposit date:2012-05-23
Release date:2013-04-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I.
Plos One, 9, 2014
4FN3
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BU of 4fn3 by Molmil
Crystal Structure of an S52A mutant of the Restriction-Modification Controller Protein C.Esp1396I
Descriptor: Regulatory protein, SULFATE ION
Authors:Martin, R.N.A, McGeehan, J.E, Kneale, G.G.
Deposit date:2012-06-19
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I.
Plos One, 9, 2014
4HK1
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BU of 4hk1 by Molmil
Crystal Structure of PCNA from Drosophila melanogaster
Descriptor: Proliferating cell nuclear antigen
Authors:Wang, K, Shi, Z.B, Zhou, Z.C.
Deposit date:2012-10-14
Release date:2013-04-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structure of PCNA from Drosophila melanogaster.
Acta Crystallogr.,Sect.F, 69, 2013
3FBR
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BU of 3fbr by Molmil
structure of HipA-amppnp-peptide
Descriptor: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase toxin HipA, peptide of EF-Tu
Authors:Schumacher, M.A.
Deposit date:2008-11-19
Release date:2009-02-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
3C3W
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BU of 3c3w by Molmil
Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR
Descriptor: SULFATE ION, TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR
Authors:Wisedchaisri, G, Wu, M, Sherman, D.R, Hol, W.G.J.
Deposit date:2008-01-28
Release date:2008-04-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the response regulator DosR from Mycobacterium tuberculosis suggest a helix rearrangement mechanism for phosphorylation activation
J.Mol.Biol., 378, 2008
4DBV
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BU of 4dbv by Molmil
GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE MUTANT WITH LEU 33 REPLACED BY THR, THR 34 REPLACED BY GLY, ASP 36 REPLACED BY GLY, LEU 187 REPLACED BY ALA, AND PRO 188 REPLACED BY SER COMPLEXED WITH NADP+
Descriptor: GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION
Authors:Didierjean, C, Rahuel-Clermont, S, Vitoux, B, Dideberg, O, Branlant, G, Aubry, A.
Deposit date:1997-01-06
Release date:1997-07-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A crystallographic comparison between mutated glyceraldehyde-3-phosphate dehydrogenases from Bacillus stearothermophilus complexed with either NAD+ or NADP+.
J.Mol.Biol., 268, 1997
2G7O
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BU of 2g7o by Molmil
Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM
Descriptor: Protein traM
Authors:Lu, J, Edwards, R.A, Wong, J.J, Manchak, J, Scott, P.G, Frost, L.S, Glover, J.N.
Deposit date:2006-02-28
Release date:2006-06-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM.
Embo J., 25, 2006
6DXL
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BU of 6dxl by Molmil
Linked amidobenzimidazole STING agonist
Descriptor: 1,1'-(butane-1,4-diyl)bis{2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-1H-benzimidazole-5-carboxamide}, CALCIUM ION, Stimulator of interferon protein
Authors:Concha, N.O.
Deposit date:2018-06-29
Release date:2018-11-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Design of amidobenzimidazole STING receptor agonists with systemic activity.
Nature, 564, 2018
2J6W
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BU of 2j6w by Molmil
R164N mutant of the RUNX1 Runt domain
Descriptor: CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1
Authors:Grembecka, J, Zhe, L, Lukasik, S.M, Liu, Y, Bielnicka, I, Bushweller, J.H, Speck, N.A.
Deposit date:2006-10-04
Release date:2007-10-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Mutation in the S-Switch Region of the Runt Domain Alters the Dynamics of an Allosteric Network Responsible for Cbfbeta Regulation.
J.Mol.Biol., 364, 2006
3DNT
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BU of 3dnt by Molmil
structures of MDT proteins
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein hipA, ...
Authors:Schumacher, M.A.
Deposit date:2008-07-02
Release date:2009-01-27
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009

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