7N3C
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![BU of 7n3c by Molmil](/molmil-images/mine/7n3c) | Crystal Structure of Human Fab S24-202 in the complex with the N-terminal Domain of Nucleocapsid protein from SARS CoV-2 | Descriptor: | 1,2-ETHANEDIOL, IODIDE ION, Nucleoprotein, ... | Authors: | Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-05-31 | Release date: | 2021-07-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies. Iscience, 27, 2024
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7U2J
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![BU of 7u2j by Molmil](/molmil-images/mine/7u2j) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Gly-NH-tRNAgly, peptidyl P-site fMAC-NH-tRNAmet, deacylated E-site tRNAgly, and chloramphenicol at 2.55A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | Deposit date: | 2022-02-24 | Release date: | 2022-07-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine. Nucleic Acids Res., 50, 2022
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7N3D
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![BU of 7n3d by Molmil](/molmil-images/mine/7n3d) | Crystal Structure of Human Fab S24-1564 in the complex with the N-terminal Domain of Nucleocapsid protein from SARS CoV-2 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Nucleoprotein, ... | Authors: | Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-05-31 | Release date: | 2021-07-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies. Iscience, 27, 2024
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7NB0
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![BU of 7nb0 by Molmil](/molmil-images/mine/7nb0) | Structure of the DNA-binding domain of SEPALLATA 3 | Descriptor: | Developmental protein SEPALLATA 3 | Authors: | Zubieta, C, Nanao, M.H. | Deposit date: | 2021-01-25 | Release date: | 2021-07-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The intervening domain is required for DNA-binding and functional identity of plant MADS transcription factors. Nat Commun, 12, 2021
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7U2I
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![BU of 7u2i by Molmil](/molmil-images/mine/7u2i) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Gly-NH-tRNAgly, aminoacylated P-site fMet-NH-tRNAmet, deacylated E-site tRNAgly, and chloramphenicol at 2.55A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | Deposit date: | 2022-02-24 | Release date: | 2022-07-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine. Nucleic Acids Res., 50, 2022
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8X1A
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![BU of 8x1a by Molmil](/molmil-images/mine/8x1a) | Crystal structure of periplasmic G6P binding protein VcA0625 | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, Iron(III) ABC transporter, periplasmic iron-compound-binding protein | Authors: | Dasgupta, J, Saha, I. | Deposit date: | 2023-11-06 | Release date: | 2024-04-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.604 Å) | Cite: | Structural insights in to the atypical type-I ABC Glucose-6-phosphate importer VCA0625-27 of Vibrio cholerae. Biochem.Biophys.Res.Commun., 716, 2024
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7MWY
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![BU of 7mwy by Molmil](/molmil-images/mine/7mwy) | |
7MWZ
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![BU of 7mwz by Molmil](/molmil-images/mine/7mwz) | |
3FRL
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![BU of 3frl by Molmil](/molmil-images/mine/3frl) | The 2.25 A crystal structure of LipL32, the major surface antigen of Leptospira interrogans serovar Copenhageni | Descriptor: | 2,2',2''-NITRILOTRIETHANOL, CHLORIDE ION, LipL32, ... | Authors: | Farah, C.S, Guzzo, C.R, Hauk, P, Ho, P.L. | Deposit date: | 2009-01-08 | Release date: | 2009-06-16 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure and calcium-binding activity of LipL32, the major surface antigen of pathogenic Leptospira sp. J.Mol.Biol., 390, 2009
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4EOY
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8W2L
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![BU of 8w2l by Molmil](/molmil-images/mine/8w2l) | TRPM7 structure in complex with anticancer agent CCT128930 in closed state | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium, ... | Authors: | Nadezhdin, K.D, Sobolevsky, A.I. | Deposit date: | 2024-02-20 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.45 Å) | Cite: | Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930. Cell Rep, 43, 2024
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7NUU
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![BU of 7nuu by Molmil](/molmil-images/mine/7nuu) | Crystal structure of human AMDHD2 in complex with Zn | Descriptor: | GLYCEROL, N-acetylglucosamine-6-phosphate deacetylase, ZINC ION | Authors: | Ruegenberg, S, Kroef, V, Baumann, U, Denzel, M.S. | Deposit date: | 2021-03-14 | Release date: | 2021-04-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.836 Å) | Cite: | GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway. Elife, 11, 2022
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7NUT
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![BU of 7nut by Molmil](/molmil-images/mine/7nut) | Crystal structure of human AMDHD2 in complex with Zn and GlcN6P | Descriptor: | 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, N-acetylglucosamine-6-phosphate deacetylase, ZINC ION | Authors: | Ruegenberg, S, Kroef, V, Baumann, U, Denzel, M.S. | Deposit date: | 2021-03-14 | Release date: | 2021-04-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.898 Å) | Cite: | GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway. Elife, 11, 2022
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7SNH
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![BU of 7snh by Molmil](/molmil-images/mine/7snh) | Structure of G6PD-D200N tetramer bound to NADP+ | Descriptor: | Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-10-28 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity. Proc.Natl.Acad.Sci.USA, 119, 2022
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7SVQ
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![BU of 7svq by Molmil](/molmil-images/mine/7svq) | Crystal Structure of L-galactose dehydrogenase from Spinacia oleracea in complex with NAD+ | Descriptor: | L-galactose dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Santillan, J.A.V, Cabrejos, D.A.L, Pereira, H.M, Gomez, J.C.C, Garratt, R.C. | Deposit date: | 2021-11-19 | Release date: | 2022-07-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Characterization of L-Galactose Dehydrogenase: An Essential Enzyme for Vitamin C Biosynthesis. Plant Cell.Physiol., 63, 2022
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7SNF
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![BU of 7snf by Molmil](/molmil-images/mine/7snf) | Structure of G6PD-WT dimer | Descriptor: | Glucose-6-phosphate 1-dehydrogenase | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-10-28 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity. Proc.Natl.Acad.Sci.USA, 119, 2022
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7SMI
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![BU of 7smi by Molmil](/molmil-images/mine/7smi) | Crystal Structure of L-galactose dehydrogenase from Spinacia oleracea | Descriptor: | L-galactose dehydrogenase | Authors: | Santillan, J.A.V, Cabrejos, D.A.L, Pereira, H.M, Gomez, J.C.C, Garratt, R.C. | Deposit date: | 2021-10-26 | Release date: | 2022-07-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Characterization of L-Galactose Dehydrogenase: An Essential Enzyme for Vitamin C Biosynthesis. Plant Cell.Physiol., 63, 2022
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7SNM
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7T64
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![BU of 7t64 by Molmil](/molmil-images/mine/7t64) | Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the closed state | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION | Authors: | Iyer, K.A, Hu, Y, Murayama, T, Samso, M. | Deposit date: | 2021-12-13 | Release date: | 2022-07-20 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM. Proc.Natl.Acad.Sci.USA, 119, 2022
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7T65
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![BU of 7t65 by Molmil](/molmil-images/mine/7t65) | Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the open state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... | Authors: | Iyer, K.A, Hu, Y, Murayama, T, Samso, M. | Deposit date: | 2021-12-13 | Release date: | 2022-07-20 | Last modified: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (4.05 Å) | Cite: | Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM. Proc.Natl.Acad.Sci.USA, 119, 2022
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8UM2
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8UM1
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7OOP
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![BU of 7oop by Molmil](/molmil-images/mine/7oop) | Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) | Descriptor: | DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ... | Authors: | Kokic, G, Cramer, P. | Deposit date: | 2021-05-28 | Release date: | 2021-10-06 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
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8U4F
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8U4A
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![BU of 8u4a by Molmil](/molmil-images/mine/8u4a) | |