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7P5V
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BU of 7p5v by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1
Descriptor: Synthetic nanobody Sb1, Volume-regulated anion channel subunit LRRC8A
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7P60
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BU of 7p60 by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb4 at 1:0.5 ratio
Descriptor: Volume-regulated anion channel subunit LRRC8A, synthetic nanobody Sb4
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
2EJG
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BU of 2ejg by Molmil
Crystal Structure Of The Biotin Protein Ligase (Mutation R48A) and Biotin Carboxyl Carrier Protein Complex From Pyrococcus Horikoshii OT3
Descriptor: 149aa long hypothetical methylmalonyl-CoA decarboxylase gamma chain, 235aa long hypothetical biotin--[acetyl-CoA-carboxylase] ligase, ADENOSINE, ...
Authors:Bagautdinov, B, Matsuura, Y, Bagautdinova, S, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-16
Release date:2008-03-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate
J.Biol.Chem., 283, 2008
7RNT
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BU of 7rnt by Molmil
CRYSTAL STRUCTURE OF THE TYR45TRP MUTANT OF RIBONUCLEASE T1 IN A COMPLEX WITH 2'-ADENYLIC ACID
Descriptor: ADENOSINE-2'-MONOPHOSPHATE, CALCIUM ION, RIBONUCLEASE T1
Authors:Koellner, G, Grunert, H.-P, Landt, O, Saenger, W.
Deposit date:1991-08-20
Release date:1993-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the Tyr45Trp mutant of ribonuclease T1 in a complex with 2'-adenylic acid.
Eur.J.Biochem., 201, 1991
2ZGW
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BU of 2zgw by Molmil
Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii Complexed with Adenosine and Biotin, Mutations R48A and K111A
Descriptor: ADENOSINE, BIOTIN, biotin--[acetyl-CoA-carboxylase] ligase
Authors:Bagautdinov, B, Matsuura, Y, Bagautdinova, S, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-01-28
Release date:2008-02-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate
J.Biol.Chem., 283, 2008
3BJI
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BU of 3bji by Molmil
Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1
Descriptor: Proto-oncogene vav, Ras-related C3 botulinum toxin substrate 1 precursor, ZINC ION
Authors:Chrencik, J.E, Brooun, A, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
Deposit date:2007-12-04
Release date:2008-07-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1.
J.Mol.Biol., 380, 2008
3B1P
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BU of 3b1p by Molmil
Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in complex with ADP-inosine
Descriptor: ADENOSINE-5'-DIPHOSPHATE, INOSINE, Ribokinase, ...
Authors:Yasutake, Y, Ota, H, Hino, E, Sakasegawa, S, Tamura, T.
Deposit date:2011-07-05
Release date:2011-11-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity
Acta Crystallogr.,Sect.D, 67, 2011
3B2T
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BU of 3b2t by Molmil
Structure of phosphotransferase
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(methyl)phosphoryl]oxy}phosphoryl]adenosine, Fibroblast growth factor receptor 2, PHOSPHATE ION
Authors:Lew, E.D, Bae, J.H, Rohmann, E, Wollnik, B, Schlessinger, J.
Deposit date:2007-10-19
Release date:2008-02-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for reduced FGFR2 activity in LADD syndrome: Implications for FGFR autoinhibition and activation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2CB8
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BU of 2cb8 by Molmil
High resolution crystal structure of liganded human L-ACBP
Descriptor: 2-METHOXYETHANOL, ACYL-COA-BINDING PROTEIN, SULFATE ION, ...
Authors:Taskinen, J.P, van Aalten, D.M, Knudsen, J, Wierenga, R.K.
Deposit date:2006-01-03
Release date:2006-10-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:High Resolution Crystal Structures of Unliganded and Liganded Human Liver Acbp Reveal a New Mode of Binding for the Acyl-Coa Ligand.
Proteins: Struct., Funct., Bioinf., 66, 2007
3B1Q
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BU of 3b1q by Molmil
Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in complex with inosine
Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ACETATE ION, INOSINE, ...
Authors:Yasutake, Y, Ota, H, Hino, E, Sakasegawa, S, Tamura, T.
Deposit date:2011-07-05
Release date:2011-11-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity
Acta Crystallogr.,Sect.D, 67, 2011
2E64
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BU of 2e64 by Molmil
Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii, Mutations R48A and K111A
Descriptor: biotin--[acetyl-CoA-carboxylase] ligase
Authors:Bagautdinov, B, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-12-25
Release date:2007-06-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate
J.Biol.Chem., 283, 2008
3B13
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BU of 3b13 by Molmil
Crystal structure of the DHR-2 domain of DOCK2 in complex with Rac1 (T17N mutant)
Descriptor: Dedicator of cytokinesis protein 2, Ras-related C3 botulinum toxin substrate 1
Authors:Hanawa-Suetsugu, K, Kukimoto-Niino, M, Mishima-Tsumagari, C, Terada, T, Shirouzu, M, Fukui, Y, Yokoyama, S.
Deposit date:2011-06-24
Release date:2012-03-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.006 Å)
Cite:Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.
Proc.Natl.Acad.Sci.USA, 109, 2012
3B7W
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BU of 3b7w by Molmil
Crystal structure of human acyl-CoA synthetase medium-chain family member 2A, with L64P mutation
Descriptor: Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor, CHLORIDE ION, ...
Authors:Pilka, E.S, Kochan, G.T, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2007-10-31
Release date:2007-11-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A.
J.Mol.Biol., 388, 2009
3B1O
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BU of 3b1o by Molmil
Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in ligand-free form
Descriptor: Ribokinase, putative
Authors:Yasutake, Y, Ota, H, Hino, E, Sakasegawa, S, Tamura, T.
Deposit date:2011-07-05
Release date:2011-11-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity
Acta Crystallogr.,Sect.D, 67, 2011
3B1N
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BU of 3b1n by Molmil
Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in complex with ADP-mizoribine
Descriptor: 5-hydroxy-1-(beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
Authors:Yasutake, Y, Ota, H, Hino, E, Sakasegawa, S, Tamura, T.
Deposit date:2011-07-05
Release date:2011-11-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity
Acta Crystallogr.,Sect.D, 67, 2011
2D5D
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BU of 2d5d by Molmil
Structure of Biotin Carboxyl Carrier Protein (74Val start) from Pyrococcus horikoshi OT3 Ligand Free Form II
Descriptor: methylmalonyl-CoA decarboxylase gamma chain
Authors:Bagautdinov, B, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-11-01
Release date:2006-05-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate
J.Biol.Chem., 283, 2008
3C5E
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BU of 3c5e by Molmil
Crystal structure of human acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in complex with ATP
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, Acyl-coenzyme A synthetase ACSM2A, ...
Authors:Pilka, E.S, Kochan, G.T, Bhatia, C, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2008-01-31
Release date:2008-02-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A.
J.Mol.Biol., 388, 2009
2ASE
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BU of 2ase by Molmil
NMR structure of the F28L mutant of Cdc42Hs
Descriptor: Cell division control protein 42 homolog
Authors:Adams, P.D, Oswald, R.E.
Deposit date:2005-08-23
Release date:2006-02-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of an Oncogenic Mutant of Cdc42Hs
Biochemistry, 45, 2006
2FJ9
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BU of 2fj9 by Molmil
High resolution crystal structure of the unliganded human ACBP
Descriptor: Acyl-CoA-binding protein, CHLORIDE ION, LEAD (II) ION, ...
Authors:Taskinen, J.P, van Aalten, D.M, Knudsen, J, Wierenga, R.K.
Deposit date:2006-01-02
Release date:2006-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High resolution crystal structures of unliganded and liganded human liver ACBP reveal a new mode of binding for the acyl-CoA ligand.
Proteins, 66, 2006
2EVB
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BU of 2evb by Molmil
Structure of Biotin Carboxyl Carrier Protein (74Val start) from Pyrococcus horikoshi OT3 Ligand Free Form I
Descriptor: methylmalonyl-CoA decarboxylase gamma chain
Authors:Bagautdinov, B, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-10-31
Release date:2006-05-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate
J.Biol.Chem., 283, 2008
2DFK
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BU of 2dfk by Molmil
Crystal structure of the CDC42-Collybistin II complex
Descriptor: GLYCEROL, SULFATE ION, cell division cycle 42 isoform 1, ...
Authors:Xiang, S, Kim, E.Y, Connelly, J.J, Nassar, N, Kirsch, J, Winking, J, Schwarz, G, Schindelin, H.
Deposit date:2006-03-02
Release date:2006-05-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Crystal Structure of Cdc42 in Complex with Collybistin II, a Gephyrin-interacting Guanine Nucleotide Exchange Factor.
J.Mol.Biol., 359, 2006
2EJF
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BU of 2ejf by Molmil
Crystal Structure Of The Biotin Protein Ligase (Mutations R48A and K111A) and Biotin Carboxyl Carrier Protein Complex From Pyrococcus Horikoshii OT3
Descriptor: 149aa long hypothetical methylmalonyl-CoA decarboxylase gamma chain, 235aa long hypothetical biotin--[acetyl-CoA-carboxylase] ligase, ADENOSINE, ...
Authors:Bagautdinov, B, Matsuura, Y, Bagautdinova, S, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-16
Release date:2008-03-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate
J.Biol.Chem., 283, 2008
2FJU
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BU of 2fju by Molmil
Activated Rac1 bound to its effector phospholipase C beta 2
Descriptor: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CALCIUM ION, ...
Authors:Jezyk, M.R, Snyder, J.T, Harden, T.K, Sondek, J.
Deposit date:2006-01-03
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Rac1 bound to its effector phospholipase C-beta2.
Nat.Struct.Mol.Biol., 13, 2006
2FQQ
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BU of 2fqq by Molmil
Crystal structure of human caspase-1 (Cys285->Ala, Cys362->Ala, Cys364->Ala, Cys397->Ala) in complex with 1-methyl-3-trifluoromethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (2-mercapto-ethyl)-amide
Descriptor: 1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE, Caspase-1
Authors:Scheer, J.M, Wells, J.A, Romanowski, M.J.
Deposit date:2006-01-18
Release date:2006-05-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A common allosteric site and mechanism in caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2QOK
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BU of 2qok by Molmil
Human EphA3 kinase and juxtamembrane region, Y596F:Y602F:S768A triple mutant
Descriptor: BETA-MERCAPTOETHANOL, Ephrin receptor
Authors:Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-20
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008

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数据于2024-09-04公开中

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