6N4K
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7SFJ
| ChRmine in MSP1E3D1 lipid nanodisc | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ChRmine, RETINAL | Authors: | Tucker, K, Brohawn, S. | Deposit date: | 2021-10-04 | Release date: | 2021-12-01 | Last modified: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Cryo-EM structures of the channelrhodopsin ChRmine in lipid nanodiscs. Nat Commun, 13, 2022
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7SHS
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7S1H
| Wild-type Escherichia coli ribosome with antibiotic linezolid | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. | Deposit date: | 2021-09-02 | Release date: | 2021-11-17 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.35 Å) | Cite: | Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
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7S78
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7SAM
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7SFK
| ChRmine in MSP1E3D1 lipid nanodisc | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ChRmine, RETINAL | Authors: | Tucker, K, Brohawn, S. | Deposit date: | 2021-10-04 | Release date: | 2021-12-01 | Last modified: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Cryo-EM structures of the channelrhodopsin ChRmine in lipid nanodiscs. Nat Commun, 13, 2022
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6N3F
| Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to SF3b1 ULM5 | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, HIV Tat-specific factor 1, ... | Authors: | Leach, J.R, Jenkins, J.L, Kielkopf, C.L. | Deposit date: | 2018-11-15 | Release date: | 2019-01-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface. J. Biol. Chem., 294, 2019
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6N3E
| Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to U2AF ligand motif 4 | Descriptor: | FORMIC ACID, GLYCEROL, HIV Tat-specific factor 1, ... | Authors: | Loerch, S, Jenkins, J.L, Kielkopf, C.L. | Deposit date: | 2018-11-15 | Release date: | 2019-01-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.893 Å) | Cite: | The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface. J. Biol. Chem., 294, 2019
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6N8G
| IRAK4 bound to benzoxazole compound | Descriptor: | Interleukin-1 receptor-associated kinase 4, N-[2-(morpholin-4-yl)-6-(piperidin-1-yl)-1,3-benzoxazol-5-yl]-6-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyridine-2-carboxamide | Authors: | Larsen, N.A, Bloudoff, K, Subramanian, V, Dobrzanska, M, Gluza, K. | Deposit date: | 2018-11-29 | Release date: | 2018-12-12 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | To be published To Be Published
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7SJR
| Cryo-EM structure of AdnA-AdnB(W325A) in complex with DNA and AMPPNP | Descriptor: | DNA (70-MER), DNA helicase, IRON/SULFUR CLUSTER, ... | Authors: | Wang, J, Warren, G.M, Shuman, S, Patel, D.J. | Deposit date: | 2021-10-18 | Release date: | 2021-12-22 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure-activity relationships at a nucleobase-stacking tryptophan required for chemomechanical coupling in the DNA resecting motor-nuclease AdnAB. Nucleic Acids Res., 50, 2022
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7SFX
| 10A1 Fab in complex with CD99 peptide | Descriptor: | 10A1 Fab heavy chain, 10A1 Fab light chain, CD99 antigen peptide | Authors: | Romero, L.A, Hattori, T, Koide, S. | Deposit date: | 2021-10-04 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | High-valency Anti-CD99 Antibodies Toward the Treatment of T Cell Acute Lymphoblastic Leukemia. J.Mol.Biol., 434, 2021
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7S1M
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7SGL
| DNA-PK complex of DNA end processing | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA-dependent protein kinase catalytic subunit, Hairpin_1, ... | Authors: | Liu, L, Li, J, Chen, X, Yang, W, Gellert, M. | Deposit date: | 2021-10-06 | Release date: | 2022-01-12 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Autophosphorylation transforms DNA-PK from protecting to processing DNA ends. Mol.Cell, 82, 2022
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7S3I
| Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex (conformer 2) | Descriptor: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Belousoff, M.J, Piper, S.J, Danev, R. | Deposit date: | 2021-09-07 | Release date: | 2022-01-05 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Structural and functional diversity among agonist-bound states of the GLP-1 receptor. Nat.Chem.Biol., 18, 2022
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7SCY
| Nuc147 bound to single BRCT | Descriptor: | DNA (147-MER), Histone H2A, Histone H2B type 1-J, ... | Authors: | Muthurajan, U.M, Rudolph, J.R. | Deposit date: | 2021-09-29 | Release date: | 2022-01-12 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer. Mol.Cell, 81, 2021
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7SCZ
| Nuc147 bound to multiple BRCTs | Descriptor: | DNA (147-MER), Histone H2A, Histone H2B type 1-J, ... | Authors: | Muthurajan, U.M, Rudolph, J. | Deposit date: | 2021-09-29 | Release date: | 2022-01-19 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer. Mol.Cell, 81, 2021
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7SJ9
| 13pf E254A microtubule from recombinant human tubulin decorated with EB3 | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Microtubule-associated protein RP/EB family member 3, ... | Authors: | LaFrance, B.J, Greber, B.J, Zhang, R, McCollum, C, Nogales, E. | Deposit date: | 2021-10-16 | Release date: | 2022-01-19 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural transitions in the GTP cap visualized by cryo-electron microscopy of catalytically inactive microtubules. Proc.Natl.Acad.Sci.USA, 119, 2022
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4I2I
| Binary complex of mouse TdT with AP5A | Descriptor: | BIS(ADENOSINE)-5'-PENTAPHOSPHATE, DNA nucleotidylexotransferase, MAGNESIUM ION, ... | Authors: | Gouge, J, Delarue, M. | Deposit date: | 2012-11-21 | Release date: | 2013-07-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
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7S1K
| Cfr-modified Escherichia coli stalled ribosome with antibiotic radezolid | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Tsai, K, Stojkovic, V, Lee, D.J, Young, I.D, Szal, T, Vazquez-Laslop, N, Mankin, A.S, Fraser, J.S, Galonic Fujimori, D. | Deposit date: | 2021-09-02 | Release date: | 2022-01-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.42 Å) | Cite: | Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
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7RY2
| mSandy2 | Descriptor: | mSandy2 | Authors: | Chica, R.A, Legault, S, Thompson, M.C. | Deposit date: | 2021-08-24 | Release date: | 2022-01-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Generation of bright monomeric red fluorescent proteins via computational design of enhanced chromophore packing. Chem Sci, 13, 2022
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7RYG
| A. baumannii Ribosome-TP-6076 complex: E-site tRNA 70S | Descriptor: | (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 16S Ribosomal RNA, 23S ribosomal RNA, ... | Authors: | Morgan, C.E, Yu, E.W. | Deposit date: | 2021-08-25 | Release date: | 2022-02-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.38 Å) | Cite: | An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
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7RYH
| A. baumannii Ribosome-TP-6076 complex: Empty 70S | Descriptor: | (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 16S Ribosomal RNA, 23S ribosomal RNA, ... | Authors: | Morgan, C.E, Yu, E.W. | Deposit date: | 2021-08-25 | Release date: | 2022-02-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
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7RYF
| A. baumannii Ribosome-TP-6076 complex: P-site tRNA 70S | Descriptor: | (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 16S Ribosomal RNA, 23S ribosomal RNA, ... | Authors: | Morgan, C.E, Yu, E.W. | Deposit date: | 2021-08-25 | Release date: | 2022-02-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
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7SKM
| Complex between S. aureus aureolysin and wt IMPI. | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Mendes, S.R, Eckhard, U, Rodriguez-Banqueri, A, Guevara, T, Gomis-Ruth, F.X. | Deposit date: | 2021-10-21 | Release date: | 2022-01-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | An engineered protein-based submicromolar competitive inhibitor of the Staphylococcus aureus virulence factor aureolysin Comput Struct Biotechnol J, 20, 2022
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