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6N8G

IRAK4 bound to benzoxazole compound

Summary for 6N8G
Entry DOI10.2210/pdb6n8g/pdb
DescriptorInterleukin-1 receptor-associated kinase 4, N-[2-(morpholin-4-yl)-6-(piperidin-1-yl)-1,3-benzoxazol-5-yl]-6-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyridine-2-carboxamide (3 entities in total)
Functional Keywordsprotein kinase, irak4, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight136309.53
Authors
Larsen, N.A.,Bloudoff, K.,Subramanian, V.,Dobrzanska, M.,Gluza, K. (deposition date: 2018-11-29, release date: 2018-12-12)
Primary citationLarsen, N.A.,Gluza, K.
To be published
To Be Published,
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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