7S1H

Wild-type Escherichia coli ribosome with antibiotic linezolid

This is a non-PDB format compatible entry.

Summary for 7S1H

• Entry DOI: 10.2210/pdb7s1h/pdb
• EMDB information: 24800 24801
• Descriptor: 30S ribosomal protein S19, 23S rRNA, 5S rRNA, ... (56 entities in total)
• Functional Keywords: escherichia coli ribosome, oxazolidinone, linezolid, ribosome-antibiotic complex, ribosome/antibiotic
• Biological source: Escherichia coli; More
• Total number of polymer chains: 52
• Total formula weight: 2144982.44

Authors

Young, I.D.,Stojkovic, V.,Tsai, K.,Lee, D.J.,Fraser, J.S.,Galonic Fujimori, D. (deposition date: 2021-09-02, release date: 2021-11-17, Last modification date: 2023-11-15)

• Primary citation: Tsai, K.,Stojkovic, V.,Lee, D.J.,Young, I.D.,Szal, T.,Klepacki, D.,Vazquez-Laslop, N.,Mankin, A.S.,Fraser, J.S.,Fujimori, D.G.; Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics.; Nat.Struct.Mol.Biol., 29:162-171, 2022; PubMed: 35165456; DOI: 10.1038/s41594-022-00723-9

Experimental method

ELECTRON MICROSCOPY (2.35 Å)