7V3A
| Crystal structure of apo-NP exonuclease C409A | Descriptor: | MAGNESIUM ION, Nucleoprotein, ZINC ION | Authors: | Hsiao, Y.Y, Huang, K.W. | Deposit date: | 2021-08-10 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7V38
| Crystal structure of NP exonuclease-PCMPS complex | Descriptor: | Nucleoprotein, PARA-MERCURY-BENZENESULFONIC ACID, ZINC ION | Authors: | Hsiao, Y.Y, Huang, K.W. | Deposit date: | 2021-08-10 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7V3C
| Crystal structure of NP exonuclease C409A-PCMB complex | Descriptor: | 4-(HYDROXYMERCURY)BENZOIC ACID, MAGNESIUM ION, Nucleoprotein, ... | Authors: | Hsiao, Y.Y, Huang, K.W. | Deposit date: | 2021-08-10 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7V37
| Crystal structure of apo-NP exonuclease | Descriptor: | Nucleoprotein, ZINC ION | Authors: | Hsiao, Y.Y, Huang, K.W. | Deposit date: | 2021-08-10 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7V39
| Crystal structure of NP exonuclease-PCMB complex | Descriptor: | 4-(HYDROXYMERCURY)BENZOIC ACID, Nucleoprotein, ZINC ION | Authors: | Hsiao, Y.Y, Huang, K.W. | Deposit date: | 2021-08-10 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7B92
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7V3B
| Crystal structure of NP exonuclease C409A-PCMPS complex | Descriptor: | MAGNESIUM ION, Nucleoprotein, PARA-MERCURY-BENZENESULFONIC ACID, ... | Authors: | Hsiao, Y.Y, Huang, K.W. | Deposit date: | 2021-08-10 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7B9C
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7B91
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1GQU
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8SQU
| Monomeric MapSPARTA bound with guide RNA and target DNA hybrid | Descriptor: | MAGNESIUM ION, TIR-APAZ, guide RNA, ... | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | Deposit date: | 2023-05-04 | Release date: | 2023-08-23 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621, 2023
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6X5N
| Crystal structure of a stabilized PAN ENE bimolecular triplex with a GC-clamped polyA tail, in complex with Fab-BL-3,6 | Descriptor: | Heavy chain Fab Bl-3 6, Light chain Fab BL-3 6, SULFATE ION, ... | Authors: | Swain, M, Li, M, Woldawer, A, LeGrice, S.F.J. | Deposit date: | 2020-05-26 | Release date: | 2020-07-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Dynamic bulge nucleotides in the KSHV PAN ENE triple helix provide a unique binding platform for small molecule ligands. Nucleic Acids Res., 49, 2021
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1HRH
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7V2Y
| cryo-EM structure of yeast THO complex with Sub2 | Descriptor: | ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2, ... | Authors: | Chen, C, Tan, M, Wu, Z, Wu, J, Lei, M. | Deposit date: | 2021-08-10 | Release date: | 2022-07-27 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural and functional insights into R-loop prevention and mRNA export by budding yeast THO-Sub2 complex. Sci Bull (Beijing), 66, 2021
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5CV3
| C. remanei PGL-1 Dimerization Domain - Hg | Descriptor: | ETHYL MERCURY ION, Putative uncharacterized protein | Authors: | Aoki, S.T, Bingman, C.A, Wickens, M, Kimble, J.E. | Deposit date: | 2015-07-25 | Release date: | 2016-02-03 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.17014766 Å) | Cite: | PGL germ granule assembly protein is a base-specific, single-stranded RNase. Proc.Natl.Acad.Sci.USA, 113, 2016
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5L1Z
| TAR complex with HIV-1 Tat-AFF4-P-TEFb | Descriptor: | AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ... | Authors: | Schulze-Gahmen, U, Hurley, J. | Deposit date: | 2016-07-29 | Release date: | 2016-10-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (5.9 Å) | Cite: | Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex. Elife, 5, 2016
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5COW
| C. remanei PGL-1 Dimerization Domain | Descriptor: | 1,2-ETHANEDIOL, Putative uncharacterized protein, SULFATE ION | Authors: | Aoki, S.T, Bingman, C.A, Wickens, M, Kimble, J.E. | Deposit date: | 2015-07-20 | Release date: | 2016-02-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | PGL germ granule assembly protein is a base-specific, single-stranded RNase. Proc.Natl.Acad.Sci.USA, 113, 2016
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1ILY
| Solution Structure of Ribosomal Protein L18 of Thermus thermophilus | Descriptor: | RIBOSOMAL PROTEIN L18 | Authors: | Woestenenk, E.A, Gongadze, G.M, Shcherbakov, D.V, Rak, A.V, Garber, M.B, Hard, T, Berglund, H. | Deposit date: | 2001-05-09 | Release date: | 2002-05-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The solution structure of ribosomal protein L18 from Thermus thermophilus reveals a conserved RNA-binding fold. Biochem.J., 363, 2002
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8H94
| Structure of mouse SCMC bound with KH domain of FILIA | Descriptor: | NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | Authors: | Chi, P, Ou, G, Han, Z, Li, J, Deng, D. | Deposit date: | 2022-10-24 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of the subcortical maternal complex and its implications in reproductive disorders. Nat.Struct.Mol.Biol., 31, 2024
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8H96
| Structure of mouse SCMC core complex | Descriptor: | NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | Authors: | Chi, P, Ou, G, Li, J, Han, Z, Deng, D. | Deposit date: | 2022-10-24 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Structural basis of the subcortical maternal complex and its implications in reproductive disorders. Nat.Struct.Mol.Biol., 31, 2024
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8H95
| Structure of mouse SCMC bound with full-length FILIA | Descriptor: | NACHT, LRR and PYD domains-containing protein 5, Oocyte-expressed protein homolog, ... | Authors: | Chi, P, Ou, G, Han, Z, Li, L, Deng, D. | Deposit date: | 2022-10-24 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Structural basis of the subcortical maternal complex and its implications in reproductive disorders. Nat.Struct.Mol.Biol., 31, 2024
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6RNQ
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4XWF
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4XW7
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2EA1
| Crystal structure of Ribonuclease I from Escherichia coli COMPLEXED WITH GUANYLYL-2(PRIME),5(PRIME)-GUANOSINE | Descriptor: | GUANYLYL-2',5'-PHOSPHOGUANOSINE, Ribonuclease I | Authors: | Zhou, K, Pan, J, Padmanabhan, S, Lim, R.W, Lim, L.W. | Deposit date: | 2007-01-29 | Release date: | 2008-01-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Ribonuclease I from Escherichia Coli Complexed with Guanylyl-2(Prime),5(Prime)-Guanosine at 1.80 Angstroms Resolution To be Published
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