1Y9I
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![BU of 1y9i by Molmil](/molmil-images/mine/1y9i) | Crystal structure of low temperature requirement C protein from Listeria monocytogenes | Descriptor: | CALCIUM ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2004-12-15 | Release date: | 2004-12-28 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of phosphatidylglycerophosphatase (PGPase), a putative membrane-bound lipid phosphatase, reveals a novel binuclear metal binding site and two "proton wires". Proteins, 64, 2006
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4YZD
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![BU of 4yzd by Molmil](/molmil-images/mine/4yzd) | Crystal Structure of human phosphorylated IRE1alpha in complex with ADP-Mg | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase/endoribonuclease IRE1 | Authors: | Concha, N.O. | Deposit date: | 2015-03-24 | Release date: | 2015-11-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1 alpha Endoribonuclease Activity. Mol.Pharmacol., 88, 2015
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1Q12
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![BU of 1q12 by Molmil](/molmil-images/mine/1q12) | Crystal Structure of the ATP-bound E. coli MalK | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Maltose/maltodextrin transport ATP-binding protein malK | Authors: | Chen, J, Lu, G, Lin, J, Davidson, A.L, Quiocho, F.A. | Deposit date: | 2003-07-18 | Release date: | 2003-09-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A tweezers-like motion of the ATP-binding cassette dimer in an ABC transport cycle Mol.Cell, 12, 2003
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2XPD
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![BU of 2xpd by Molmil](/molmil-images/mine/2xpd) | Reduced Thiol peroxidase (Tpx) from yersinia Pseudotuberculosis | Descriptor: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, THIOL PEROXIDASE | Authors: | Gabrielsen, M, Zetterstrom, C.E, Wang, D, Elofsson, M, Roe, A.J. | Deposit date: | 2010-08-26 | Release date: | 2011-06-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Characterisation of Tpx from Yersinia Pseudotuberculosis Reveals Insights Into the Binding of Salicylidene Acylhydrazide Compounds. Plos One, 7, 2012
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5YZC
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![BU of 5yzc by Molmil](/molmil-images/mine/5yzc) | Crystal structure of the prefusion form of measles virus fusion protein in complex with a fusion inhibitor compound (AS-48) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-nitro-2-[(phenylacetyl)amino]benzamide, ... | Authors: | Hashiguchi, T, Fukuda, Y, Matsuoka, R, Kuroda, D, Kubota, M, Shirogane, Y, Watanabe, S, Tsumoto, K, Kohda, D, Plemper, R.K, Yanagi, Y. | Deposit date: | 2017-12-14 | Release date: | 2018-02-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.334 Å) | Cite: | Structures of the prefusion form of measles virus fusion protein in complex with inhibitors. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1NBE
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1LI1
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![BU of 1li1 by Molmil](/molmil-images/mine/1li1) | The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link | Descriptor: | ACETATE ION, Collagen alpha 1(IV), Collagen alpha 2(IV) | Authors: | Than, M.E, Henrich, S, Huber, R, Ries, A, Mann, K, Kuhn, K, Timpl, R, Bourenkov, G.P, Bartunik, H.D, Bode, W. | Deposit date: | 2002-04-17 | Release date: | 2002-05-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link. Proc.Natl.Acad.Sci.USA, 99, 2002
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6CNN
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1XCB
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![BU of 1xcb by Molmil](/molmil-images/mine/1xcb) | X-ray Structure of a Rex-Family Repressor/NADH Complex from Thermus Aquaticus | Descriptor: | CALCIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Redox-sensing transcriptional repressor rex | Authors: | Sickmier, E.A, Brekasis, D, Paranawithana, S, Bonanno, J.B, Burley, S.K, Paget, M.S, Kielkopf, C.L, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2004-09-01 | Release date: | 2004-09-28 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | X-Ray Structure of a Rex-Family Repressor/NADH Complex: Insights into the Mechanism of Redox Sensing Structure, 13, 2005
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1NHV
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![BU of 1nhv by Molmil](/molmil-images/mine/1nhv) | Hepatitis C virus RNA polymerase in complex with non-nucleoside analogue inhibitor | Descriptor: | (2S)-2-[(5-BENZOFURAN-2-YL-THIOPHEN-2-YLMETHYL)-(2,4-DICHLORO-BENZOYL)-AMINO]-3-PHENYL-PROPIONIC ACID, HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE | Authors: | Wang, M, Ng, K.K.S, Cherney, M.M, Chan, L, Yannopoulos, C.G, Bedard, J, Morin, N, Nguyen-Ba, N, Alaoui-Ismaili, M.H, Bethell, R.C, James, M.N.G. | Deposit date: | 2002-12-19 | Release date: | 2003-03-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Non-Nucleoside Analogue Inhibitors Bind to an Allosteric Site on
HCV NS5B Polymerase: Crystal Structures and Mechanism of Inhibition J.Biol.Chem., 278, 2003
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1KFC
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![BU of 1kfc by Molmil](/molmil-images/mine/1kfc) | CRYSTAL STRUCTURE OF ALPHAT183V MUTANT OF TRYPTOPHAN SYNTHASE FROM SALMONELLA TYPHIMURIUM With Indole Propanol Phosphate | Descriptor: | INDOLE-3-PROPANOL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | Authors: | Kulik, V, Weyand, M, Siedel, R, Niks, D, Arac, D, Dunn, M.F, Schlichting, I. | Deposit date: | 2001-11-20 | Release date: | 2003-01-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | On the Role of AlphaTHR183 in the Allosteric Regulation and Catalytic Mechanism of Tryptophan Synthase J.Mol.Biol., 324, 2002
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2W0K
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1KFE
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![BU of 1kfe by Molmil](/molmil-images/mine/1kfe) | CRYSTAL STRUCTURE OF ALPHAT183V MUTANT OF TRYPTOPHAN SYNTHASE FROM SALMONELLA TYPHIMURIUM WITH L-Ser Bound To The Beta Site | Descriptor: | SODIUM ION, TRYPTOPHAN SYNTHASE ALPHA CHAIN, TRYPTOPHAN SYNTHASE BETA CHAIN, ... | Authors: | Kulik, V, Weyand, M, Siedel, R, Niks, D, Arac, D, Dunn, M.F, Schlichting, I. | Deposit date: | 2001-11-20 | Release date: | 2003-01-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | On the Role of AlphaTHR183 in the Allosteric Regulation and Catalytic Mechanism of Tryptophan Synthase J.Mol.Biol., 324, 2002
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4Z1M
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![BU of 4z1m by Molmil](/molmil-images/mine/4z1m) | Bovine F1-ATPase inhibited by three copies of the inhibitor protein IF1 crystallised in the presence of thiophosphate. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ... | Authors: | Bason, J.V, Montgomery, M.G, Leslie, A.G.W, Walker, J.E. | Deposit date: | 2015-03-27 | Release date: | 2015-05-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | How release of phosphate from mammalian F1-ATPase generates a rotary substep. Proc.Natl.Acad.Sci.USA, 112, 2015
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4ICY
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![BU of 4icy by Molmil](/molmil-images/mine/4icy) | Tracing the Evolution of Angucyclinone Monooxygenases: Structural Determinants for C-12b Hydroxylation and Substrate Inhibition in PgaE | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Kallio, P, Patrikainen, P, Belogurov, G, Mantsala, P, Yang, K, Niemi, J, Metsa-Ketela, M. | Deposit date: | 2012-12-11 | Release date: | 2013-06-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Tracing the Evolution of Angucyclinone Monooxygenases: Structural Determinants for C-12b Hydroxylation and Substrate Inhibition in PgaE. Biochemistry, 52, 2013
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1QHX
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1LTA
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![BU of 1lta by Molmil](/molmil-images/mine/1lta) | 2.2 ANGSTROMS CRYSTAL STRUCTURE OF E. COLI HEAT-LABILE ENTEROTOXIN (LT) WITH BOUND GALACTOSE | Descriptor: | HEAT-LABILE ENTEROTOXIN, SUBUNIT A, SUBUNIT B, ... | Authors: | Merritt, E.A, Sixma, T.K, Kalk, K.H, Van Zanten, B.A.M, Hol, W.G.J. | Deposit date: | 1993-09-15 | Release date: | 1994-01-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Galactose-binding site in Escherichia coli heat-labile enterotoxin (LT) and cholera toxin (CT). Mol.Microbiol., 13, 1994
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1ZT3
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![BU of 1zt3 by Molmil](/molmil-images/mine/1zt3) | C-terminal domain of Insulin-like Growth Factor Binding Protein-1 isolated from human amniotic fluid | Descriptor: | 1,4-DIETHYLENE DIOXIDE, Insulin-like growth factor binding protein 1 | Authors: | Sala, A, Capaldi, S, Campagnoli, M, Faggion, B, Labo, S, Perduca, M, Romano, A, Carrizo, M.E, Valli, M, Visai, L, Minchiotti, L, Galliano, M, Monaco, H.L. | Deposit date: | 2005-05-26 | Release date: | 2005-06-28 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and Properties of the C-terminal Domain of Insulin-like Growth Factor-binding Protein-1 Isolated from Human Amniotic Fluid J.Biol.Chem., 280, 2005
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1L9X
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![BU of 1l9x by Molmil](/molmil-images/mine/1l9x) | Structure of gamma-Glutamyl Hydrolase | Descriptor: | BETA-MERCAPTOETHANOL, gamma-glutamyl hydrolase | Authors: | Li, H, Ryan, T.J, Chave, K.J, Van Roey, P. | Deposit date: | 2002-03-26 | Release date: | 2002-04-10 | Last modified: | 2021-04-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Three-dimensional structure of human gamma -glutamyl hydrolase. A class I glatamine amidotransferase adapted for a complex substate. J.Biol.Chem., 277, 2002
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1ZR0
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![BU of 1zr0 by Molmil](/molmil-images/mine/1zr0) | Crystal Structure of Kunitz Domain 1 of Tissue Factor Pathway Inhibitor-2 with Bovine Trypsin | Descriptor: | CALCIUM ION, Cationic trypsin, Tissue factor pathway inhibitor 2 | Authors: | Schmidt, A.E, Chand, H.S, Cascio, D, Kisiel, W, Bajaj, S.P. | Deposit date: | 2005-05-18 | Release date: | 2005-06-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin. Implications for KD1 specificity of inhibition J.Biol.Chem., 280, 2005
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1ZT5
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![BU of 1zt5 by Molmil](/molmil-images/mine/1zt5) | C-terminal domain of Insulin-like Growth Factor Binding Protein-1 isolated from human amniotic fluid complexed with Iron(II) | Descriptor: | 1,4-DIETHYLENE DIOXIDE, FE (II) ION, Insulin-like growth factor binding protein 1 | Authors: | Sala, A, Capaldi, S, Campagnoli, M, Faggion, B, Labo, S, Perduca, M, Romano, A, Carrizo, M.E, Valli, M, Visai, L, Minchiotti, L, Galliano, M, Monaco, H.L. | Deposit date: | 2005-05-26 | Release date: | 2005-06-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.818 Å) | Cite: | Structure and Properties of the C-terminal Domain of Insulin-like Growth Factor-binding Protein-1 Isolated from Human Amniotic Fluid J.Biol.Chem., 280, 2005
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1ZU1
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![BU of 1zu1 by Molmil](/molmil-images/mine/1zu1) | Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa | Descriptor: | RNA binding protein ZFa, ZINC ION | Authors: | Moller, H.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | Deposit date: | 2005-05-29 | Release date: | 2005-09-20 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the N-terminal zinc fingers of the Xenopus laevis double-stranded RNA-binding protein ZFa J.Mol.Biol., 351, 2005
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1QKL
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![BU of 1qkl by Molmil](/molmil-images/mine/1qkl) | hRPABC14.4, essential subunit of human RNA polymerases I, II and III | Descriptor: | DNA-DIRECTED RNA POLYMERASE II 14.4 KD POLYPEPTIDE | Authors: | Del Rio-Portilla, F, Gaskell, A.G, Gilbert, D, Ladias, J.A.A, Wagner, G. | Deposit date: | 1999-07-26 | Release date: | 1999-11-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Hrpabc14.4 Subunit of Human RNA Polymerases Nat.Struct.Biol., 6, 1999
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1QPP
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1O7X
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![BU of 1o7x by Molmil](/molmil-images/mine/1o7x) | Citrate synthase from Sulfolobus solfataricus | Descriptor: | CITRATE SYNTHASE | Authors: | Bell, G.S, Russell, R.J.M, Connaris, H, Hough, D.W, Danson, M.J, Taylor, G.L. | Deposit date: | 2002-11-19 | Release date: | 2002-12-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Stepwise Adaptations of Citrate Synthase to Survival at Life'S Extremes. From Psychrophile to Hyperthermophile. Eur.J.Biochem., 269, 2002
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