5YZC
Crystal structure of the prefusion form of measles virus fusion protein in complex with a fusion inhibitor compound (AS-48)
Summary for 5YZC
Entry DOI | 10.2210/pdb5yzc/pdb |
Related | 5YXW |
Descriptor | glycoprotein F2, glycoprotein F1,measles virus fusion protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | glycoprotein, viral protein, fusion protein, paramyxovirus, inhibitor, chemical compound |
Biological source | Measles virus (strain Ichinose-B95a) (MeV) More |
Cellular location | Virion membrane ; Single-pass type I membrane protein : Q786F3 |
Total number of polymer chains | 2 |
Total formula weight | 56395.10 |
Authors | Hashiguchi, T.,Fukuda, Y.,Matsuoka, R.,Kuroda, D.,Kubota, M.,Shirogane, Y.,Watanabe, S.,Tsumoto, K.,Kohda, D.,Plemper, R.K.,Yanagi, Y. (deposition date: 2017-12-14, release date: 2018-02-21, Last modification date: 2023-11-22) |
Primary citation | Hashiguchi, T.,Fukuda, Y.,Matsuoka, R.,Kuroda, D.,Kubota, M.,Shirogane, Y.,Watanabe, S.,Tsumoto, K.,Kohda, D.,Plemper, R.K.,Yanagi, Y. Structures of the prefusion form of measles virus fusion protein in complex with inhibitors. Proc. Natl. Acad. Sci. U.S.A., 115:2496-2501, 2018 Cited by PubMed: 29463726DOI: 10.1073/pnas.1718957115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.334 Å) |
Structure validation
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