5YZC
Crystal structure of the prefusion form of measles virus fusion protein in complex with a fusion inhibitor compound (AS-48)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | glycoprotein F2 | polymer | 94 | 10524.3 | 1 | UniProt (Q786F3) | Measles virus (strain Ichinose-B95a) (MeV) | |
| 2 | B (B) | glycoprotein F1,measles virus fusion protein | polymer | 419 | 44925.9 | 1 | UniProt (Q786F3) Pfam (PF00523) | Measles virus (strain Ichinose-B95a) (MeV) | |
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E (B) | 4-nitro-2-[(phenylacetyl)amino]benzamide | non-polymer | 299.3 | 1 | Chemie (95C) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A: 20 - 112 (UniProt: Q786F3)
B: 113 - 482 (UniProt: Q786F3)
B: 483 - 531 (PDB: 5YZC)
| PDB | External Database | Details |
|---|---|---|
| Gly 19 | - | expression tag |
B: 483 - 531 (PDB: 5YZC)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55450.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 520.5 | |
| All* | Total formula weight | 56395.1 |
